Sentences with phrase «stem cell subtype»

He conducted his postdoctoral research at Brigham and Women's Hospital / Harvard Medical School, where he researched the role of the Wnt signaling pathway in mouse models of kidney disease, and was part of a team that discovered a stem cell subtype responsible for solid organ fibrosis.

Not exact matches

The physician scientists sought to identify glioblastoma subtype - specific cancer stem cells.

This study shows that the mesenchymal subtype is the most aggressive subtype, that it has the poorest prognosis among affected patients, and that cancer stem cells isolated from the mesenchymal subtype have significantly higher levels of the enzyme ALDH1A3 compared with the proneural subtype.

«Certain subtypes of leukemia are very hard to treat and typically children with these subtypes have poor prognosis,» said Dr. Dinesh Rao, the study's senior author and a member of the UCLA Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research.

«Our study suggests that if a cancer - causing mutation occurs in the neural stem cell population in the SVZ, it gives rise to the proneural or the neural glioblastoma subtype.

«There is growing evidence that breast cancer consists of different subtypes of cells including non-cancer stem cells and cancer stem cells,» said Ince, who is also associate professor of pathology at the University of Miami Miller School of Medicine.

«Areas of glioblastoma tumors correlate with separate subtypes of glioma stem cells.»

Combinatorial analysis of developmental cues efficiently converts human pluripotent stem cells into multiple neuronal subtypes.

In culture, neural stem cells (NSCs) can readily differentiate into neuronal and glial subtypes, but their ability to differentiate into region - specific neuronal cell types is limited.

Neuregulin / ErbB Signaling Regulates Cardiac Subtype Specification in Differentiating Human Embryonic Stem Cells.

A common misconception about the research field is that a tumor stem cell is actually a subtype of stem cell and that hence, cancer derives from stem cells.

Future therapies will have to be based on strategies that act by reducing or increasing the number or activity of specific subtypes of pre - and postsynaptic receptors, transporters, and ion channels, or other membrane molecules at the synapse, and by strategies that exploit the new possibilities offered by stem cell technology and targeted repair.

The signatures of the breast stem cells in the fetus were stunningly similar to the stem - like cells found in aggressive breast cancers, including a significant fraction of a virulent cancer subtype known as «triple - negative.»