Sentences with phrase «stem cell systems»

We will mine and exploit information from studies and screens in model organisms, but our primary focus is on the paradigmatic mammalian stem cell systems - haematopoiesis and epithelia in vivo, and embryonic and neural stem cells in vitro.

«People see it as worthwhile to have the peace of mind of knowing something is very similar batch to batch and has been thoroughly quality controlled,» says Joydeep Goswami, Invitrogen's vice president and general manager of primary and stem cell systems.

«Not only is regenerative medicine a fast - growing market,» notes Joydeep Goswami, vice president of primary and stem cell systems at Invitrogen in Carlsbad, California, «but the possibilities are really endless in terms of what scientists can achieve and what they can do with their work.

Eager to sort through the pile of curriculum vitae's on his desk, Rudnicki is particularly looking for molecular geneticists working on different stem cell systems; scientists with genomics bents like proteomics, microarray analysis, and bioinformatics; and a couple of clinician scientists.

Not exact matches

Panoskaltsis - Mortari's team has been working on rebuilding lungs and other parts of the respiratory system using human stem cells.

One day, Reynolds says, a version of InVivo's implant, packed with stem cells or hormones, might help the six million Americans who are chronically paralyzed from SCI and other central nervous system disorders improve their level of functioning.

That's why there is so much prejudice aimed at gays, pro-choicers, stem cell researchers, family planning or followers of other belief systems.

Adding to this, they are anti-embryonic stem cell research, because they believe a zygote (pre-cerebreal cortex, nervous system and brain) is a human being.

Like attempting to insert religion into the school system, stymie medical research aka stem cells, restrict a woman's reproductive rights... etc..

Injections of killed stem cells, designed to help the immune system recognise cancers, have been found to protect mice from developing tumours

Some scientists had claimed that the lymphatic system was derived from specialized stem cells called angioblasts, whereas others had argued that it originated by the differentiation of pre-existing embryonic veins.

Cancer cells which arise due to genetic mutations are just such cells, and there are studies which suggest that microchimeric cells may stimulate the immune system to stem the growth of tumors.

When blank slate stem cells are exposed to a soft as opposed to a hard surface on which to grow, they begin to transform themselves into neurons, the large, complex cells of the central nervous system.

We believe that they will also lead to the development of a whole new range of therapies for neurodegenerative diseases of the central nervous system,» explains corresponding author of the study Jihwan Song, professor and director of Neural Regeneration and Therapy Group at the CHA Stem Cell Institute of CHA University.

«Cardiac stem cells from heart disease patients may be harmful: Researchers discover molecular pathway involved in toxic interaction between host cells and immune system.»

But scientists are making progress in refining these therapies, and the first ever trial of fetal stem cells injected directly into the brain is currently under way in children with Batten disease, a rare and fatal illness of the nervous system.

If we can boost the immune system and allow microglia to do their job and control brain tumor stem cells, it would be like removing the seed from the soil — stopping the tumor growth before it starts to get out of control.»

Finally, the team grew the tissue in a three - dimensional system, which coaxed it into forming all the structures found in gut tissue, including the finger - like villi that protrude inwards to increase surface area, and recesses called crypts containing the intestinal stem cells that renew the gut lining weekly (Nature, DOI: 10.1038 / nature09691).

«Once inside the cells of the root, water enters into a system of interconnected cells that make up the wood of the tree and extend from the roots through the stem and branches and into the leaves.

The authors believe that these tools and methods will lay the foundation for crucial breakthroughs in the flatworm model system and in our understanding of stem cell biology and the process of regeneration.

With additional genome tinkering to avoid rejection by the immune system, they could be used clinically as a universal stem cell therapy.

Hoping to treat the fetus when its immune system was especially primitive and the disease in a nascent stage, doctors infused stem cells into the fetus's abdominal cavity at just 12 weeks» gestation.

Some may stem directly from how the altered digestive system works — secreting different levels of hormones, for example — or changes in nerve cells that communicate with the gut.

Systems biologist Prof. Thomas Höfer and colleagues (also of the DKFZ) performed mathematical analysis of these experimental data to provide additional insight into blood stem cell dynamics.

Doctors gave the patients stem cells containing copies of a properly functioning gene for the enzyme; the babies» immune systems were then able to reconstitute themselves.

Joseph Wu of Stanford University, California, and his team have found that a mouse's immune system can be primed to recognise and target cancer cells by vaccinating them beforehand with stem cells.

During embryonic development of mice, however, the situation is different: To build up the system, all mature blood and immune cells develop much more rapidly and almost completely from stem cells.

They've figured out how to turn human stem cells into functional pancreatic β cells — the same cells that are destroyed by the body's own immune system in type 1 diabetes patients.

More recently, researchers have induced stem cells from diseased human somatic cells, which may serve as new model systems for various illnesses.

«New gene editing technique turns human pluripotent stem cells into a model system for polycystic kidney disease.»

In a related paper published online today in Nature Biotechnology, Konrad Hochedlinger of the Harvard Stem Cell Institute in Cambridge and his colleagues compared the gene expression patterns in mouse iPS cells derived from white blood cells, muscle precursor cells, immune system cells called B cells, and fibroblasts taken from tail tips.

Then the stem cells release the interleukin, which is like a beacon to tell the immune system to come in and attack, right here.

Those at highest risk are people whose immune systems are suppressed, such as those undergoing stem cell and lung and other organ transplants.

To alter the stem cells, Kan's team turned to the CRISPR - Cas9 system, a super-efficient method of genome editing based on an ancient bacterial «immune system».

In the context of the current study, the researchers have developed a pre-clinical model system that specifically captures the impact of a treatment on cancer stem cells.

The transplanted stem cells differentiated to different types of cells with variable level of maturation, specific for the nervous system.

To alter the stem cells, Kan's team turned to the CRISPR - Cas9 system, a method of genome editing based on a bacterial «immune system».

2 - D cell - culture and mouse experiments also provided key evidence of the virus's modus operandi; although the rodent brain doesn't harbor the full contingent of human neural stem cells, it has blood vessels and immune - system components that organoids lack.

In addition to suppressing the mature blood cells battling against the infection, malfunctioning of this signaling system results in permanent damage to the body's blood producing cells — called hematopoietic stem cells — that are located in the bone marrow.

«This pilot study showed that the culture system not only allowed for efficient propagation of sperm stem cells, but also eliminated ALL cells,» said Sadri - Ardekani.

In the adult central nervous system, the vasculature of the neurogenic niche regulates neural stem cell behavior by providing circulating and secreted factors.

His postdoc characterizing human embryonic stem cells resulted in seven papers and a contract position at the Center for Cancer Systems Biology at Tufts University School of Medicine in 2009.

For many scientists, the clinical promise of stem cells has been dampened by very real concerns that the immune system will reject the transplanted cells before they could render any long - term benefit.

Instead, they discovered that Tregs trigger stem cell activation directly through a common cell - cell communication system known as the Notch pathway.

The findings, published today in Nature, demonstrate that these myeloproliferative neoplasias only appear after damage to the microenvironment that sustains and controls the hematopoietic stem cells — the cells that produce the cells of the blood and the immune system.

«Active HSCs (hematopoietic stem cells) form the daily supply line that continually replenishes worn - out blood and immune cells while the reserve pool serves as a backup system that replaces damaged active HSCs and steps in during times of increased need,» explains Li.

They observed two types of stem cells — ASCL - 2 positive and BMI - 1 positive — in the pig colon, similar to the human system.

Stephen Davies, a neuroscientist at the University of Colorado at Denver who studies nervous system regeneration using stem cells, is one of the key scientists working to overcome the obstacles in place.

Adult and larval fruit fly nervous systems develop from the same set of stem cells known as neuroblasts.

The study developed a new in vitro system made from bone marrow stem cells and studied what would happen if its ambient temperature fell below 37 °C (the natural temperature of the human body).