Sentences with phrase «stem cell transformation»

Not exact matches

Adenovirus 36 has been found to encourage the transformation of adult stem cells in fatty tissue into fat cells as discussed on the daily Scientific American podcast 60 - Second Science on August 20th.

This fits with studies we've conducted in the past in which we found that the gene primes blood stem cells for leukaemic transformation.»

«Overall, our data suggest that a novel signaling mechanism underlies the transformation of proneural glioma stem cells to mesenchymal - like cells and their maintenance as stem - like cells,» Nakano says.

«The spectrum of tissues at risk for transformation when harboring a p53 mutation include many of those that we would like to target for repair with regenerative medicine using human pluripotent stem cells,» said Eggan.

In a new Cell Reports paper, a team led by John P. Cooke, M.D., Ph.D., of the Houston Methodist Research Institute, has identified and characterized a biological factor critical to the transformation of adult somatic cells (cells that are not sperm or egg cells) into stem cells.

The presence of the protein β1 - integrin was shown to help promote the transformation of those undifferentiated stem cells into muscle after the tissue has degraded, and improve regenerated muscle fiber growth as much as 50 percent.

Bone marrow - derived mesenchymal stem cells undergo JCV T - antigen mediated transformation and generate tumors with neuroectodermal characteristics.

In the October issue of Cell Stem Cell, Marius Wernig, MD, PhD, a NYSCF — Robertson Investigator at Stanford University, reported on the successful transformation of mature liver cells from laboratory mice into functioning neurons.

The Herlyn lab is differentiating multi-potent stem cells from the human dermis and reprogrammed stem cells into melanocytes to test the hypothesis that melanocyte stem cells are more prone to transformation than fully differentiated cells, and that neighboring cells and matrix in the microenvironment play critical roles in differentiation and transformation.

Melton is also a pioneer in direct cellular reprogramming research — the transformation of one type of adult cell into another, without first going through a stem cell state.

Some of their goals include the unravelling of disease mechanisms by using nanomaterials to track cellular components and probe the chemical niche of the cells, the transformation of adult human cells into induced pluripotent stem cells and the delivery of drugs directly to immune and cancer cells.

The presence of Stem Cells in the ovaries and their transformation into mature oocytes (egg cells) has been demonstrated in mice by Harvard researcCells in the ovaries and their transformation into mature oocytes (egg cells) has been demonstrated in mice by Harvard researccells) has been demonstrated in mice by Harvard researchers.

Together, we provide evidence that senescence and a stem cell - associated SASP drive cell transformation and tumour initiation in vivo in an age - dependent fashion.