27) Sato, T., Vries, R., Snippert, H., van de Wetering, M., Barker, N., Stange, D., van Es, J., Abo, A., Kujala, P., Peters, P., and Clevers, H. Single lgr5 gut
stem cells build crypt - villus structures in vitro without a stromal niche 459 (7244): 262 - 5 Nature 459: 262 - 5 (2009)
The role of these gels is to mimic the natural environment of the stem cells, which provides them with a protein - and sugar - rich scaffold called the «extracellular matrix,» upon which
the stem cells build specific body tissues.
Single Lgr5
stem cells build crypt - villus structures in vitro without a mesenchymal niche.
Not exact matches
If you approve of planes flying into
buildings, dressing women in cloth bags, denying
stem cell research, discrimination against women, gays and anyone with alternate beliefs, denying contraception to people who can't afford families, picketing soldiers funerals, etc, etc, then keep your fuzzy mindset about good and evil.
Cord blood includes potent
stem cells, which are considered to be the
building blocks of the body.
Recently it has been shown that it also contains
stem cells, the universal
building blocks for growth and development.
Stem cells are unique because they are essentially the body's
building blocks; these are the only
cells in the human body that have the ability to regenerate more
cells with specialized functions.
As well as allowing the use of
stem cells grown from established
cell lines, the technology could enable the creation of improved human tissue models for drug testing and potentially even purpose -
built replacement organs.
«Several unusual nucleobases have been found in the genomes of
stem cells, which are produced by targeted chemical modification of the known
building blocks of DNA.
Scott, with Stanford's Program on
Stem Cells and Society, says that positive results could fire up patient advocacy groups, which can be powerful in
building support.
For that very reason, Magnus says, «various constraints and strict rules have been
built in to provide a very measured way of dealing with
stem cell research.»
Within the outer structure, calcium phosphate minerals help
stem cells from the host grow into
cells that help
build bone.
California's
stem cell agency has funded new facilities, providing $ 50 million for the Lorry I. Lokey Stem Cell Research Building at Stanford University, for exam
stem cell agency has funded new facilities, providing $ 50 million for the Lorry I. Lokey Stem Cell Research Building at Stanford University, for exam
cell agency has funded new facilities, providing $ 50 million for the Lorry I. Lokey
Stem Cell Research Building at Stanford University, for exam
Stem Cell Research Building at Stanford University, for exam
Cell Research
Building at Stanford University, for example.
Varghese and her team showed that they could control the differentiation of human pluripotent
stem cells into functional osteoblasts — bone -
building cells — simply by adding the molecule adenosine to their growth medium.
The
cells used to
build the organs could be cultured from
stem cells taken from fat or bone - marrow tissue, he says: «We could engineer a blood vessel from your own
cells.»
«Researchers use a single molecule to command
stem cells to
build new bone.»
During embryonic development of mice, however, the situation is different: To
build up the system, all mature blood and immune
cells develop much more rapidly and almost completely from
stem cells.
«We have just allocated $ 271 million in funds, which leveraged over $ 500 million from donors and the institutions» own reserves to
build 12
stem cell institutes in California; these are really large institutes that will accommodate a very large number of scientists,» says Trounson, an Australian native who pioneered in vitro fertilization in the 1980s and relocated to California to head up the CIRM in December 2007.
«We believe that our experiments provide the first example of a factor that both expands the intestinal
stem cell compartment and
builds a niche.»
From the French word nicher, which means to
build a nest, a niche is a nest - like compartment comprised of
cells that secrete growth factors and other proteins that help
stem cells survive.
«We suspected that HMGA1 might generate new
stem cells, but we were extremely surprised that it also helps support these
cells by
building a niche,» Resar says.
Stem cells, the blank slate from which the body can
build any type of
cell it needs, are proving themselves capable of doing what was once thought impossible: healing broken brains.
SAN FRANCISCO, CALIFORNIA — A
stem cell research
building opened today at the University of California, San Francisco (UCSF), is generating oohs and ahhs from scientists and architecture buffs alike.
Kotton
built a reporter gene that glowed green when the
stem cells first expressed Nkx2 - 1, and Hawkins engineered the same gene into human
cells.
The Lokey
Stem Cell Research
Building at Stanford University houses research conducted by the Ludwig Center for Cancer
Stem Cell Research and Medicine.
Lütolf's lab found that this attachment itself is immensely important for growing organoids, as it triggers a whole host of signals to the
stem cell that tell it to grow and
build an intestine - like structure.
What's more, these glial
cells were the ones that specifically
build the scaffolding for the motor neurons that were born from the same
stem cells and ultimately control leg movement.
«Scientists discover
stem cells that
build a fly's nervous system: Study in fruit flies sheds light on key aspect of development; findings could
build understanding of comparable system in people.»
If delay is a moral issue, it is one that has been
built into the
stem cell debate from the beginning.
«3 - D printed «
building blocks» of life: Scientists have developed a 3 - D printing method capable of producing highly uniform «blocks» of embryonic
stem cells.»
The researchers then confirmed with a controlled experiment that environmental cues were likely to have caused the effect: participants who were primed with images of churches proved less likely to support a
stem cell initiative than were subjects who were shown more neutral images, such as office
buildings.
The new approach
builds on information gleaned from developmental studies of embryonic
stem cells (see story # 16) and one day may be used to create healthy replacements for harmed or diseased tissue.
According to
stem cell researcher Diane Krause: «All research in the Amistad
Building is at a standstill — even people who need reagents for an ongoing clinical trial are unable to have access as of now.»
Goldman's work
builds on previous studies that explored the developmental cues involved in directing an embryonic
stem cell to become a functioning neuron.
«Teaching
stem cells to
build muscle: New research shows young muscle
stem cells can improve adult muscle regeneration.»
M: In Britain we had three years of debate over
stem cells,
building on earlier debates such as in vitro fertilization.
Working with Bhaduri, who has a background in statistics and bioinformatics, Pollen and Nowakowski began exploring how specific classes of neurons and
stem cells in the developing brain contribute to normal brain growth as well as to neurodevelopmental disease, and have begun to
build a comprehensive, open - source atlas of gene expression across the developing brain, which they hope will serve as a resource for other scientists.
«This information yields new insights into how sperm
stem cells function and develop under normal circumstances,» says the study's lead author Bradley Cairns, PhD, senior director of basic science at HCI and professor and chair of oncological sciences at the U of U. «We have
built a very important framework we can now use to help us understand what happens when things go wrong, resulting in issues like infertility and cancer in men.»
In myotonic dystrophy and other related neurological disorders, the symptoms
stem from repeated individual nucleotides, or «
building blocks,» in the RNA in muscle tissue
cells that can
build up over time.
Research conducted at Japan's National Institute for Materials Science
built on previous findings that gold nanoparticles can encourage
stem cells in the bone marrow to differentiate into bone
cells, and that specific biomolecules can inhibit or promote
stem cell differentiation.
To learn more, her group, including postdoctoral fellow Maria Fernanda Forni, who studies skin
stem cells, paired up with Jorge Shinohara in Sao Paulo's Fundamental Chemistry Department, who
built a custom - made temperature sensor for mouse skin.
«To
build tissues, we need to be able to take
stem cells and use them to make many different
cell types which are grouped together in particular spatial patterns,» explained Andres M. Bratt - Leal, the paper's first author and a former graduate student in McDevitt's lab.
In 5 years as inaugural director of USC's Eli and Edythe Broad Center of Regenerative Medicine and
Stem Cell Research, Pera built a stem cell program spanning basic research to clinical tri
Stem Cell Research, Pera built a stem cell program spanning basic research to clinical tri
Cell Research, Pera
built a
stem cell program spanning basic research to clinical tri
stem cell program spanning basic research to clinical tri
cell program spanning basic research to clinical trials.
The research
builds on the team's previous work with a technique called three - dimensional culture, which involves incubating
stem cells in a floating ball - shaped aggregate, unlike traditional
cell culture in which
cells grow in a flat layer on the surface of a culture dish.
When inserted into the body,
stem cells latch onto the structure and differentiate into
cells that start to
build bone, much as construction workers assemble walls, floors, and glass around a skyscraper's steel girders.
«Going back through a pluripotent
stem cell phase is a bit like demolishing a house and
building a new one from the ground up,» Yoo said.
Studying a new type of pinhead - size, lab - grown brain made with technology first suggested by three high school students, Johns Hopkins researchers have confirmed a key way in which Zika virus causes microcephaly and other damage in fetal brains: by infecting specialized
stem cells that
build its outer layer, the cortex.
Doctors
built a trachea for Hannah by creating a «scaffold» or windpipe mold out of non-absorbable nanofibers and seeding it with
stem cells from her bone marrow.
As we age, we lose mesenchymal
stem cells, so bone tissue
building slows down.
But, it was known that when HIF - 1 normally activates signals in the body to
build new vessels, one of the many types of
cells recruited to the site of new vessel growth is a population of
stem cells from the bone marrow, which are called bone marrow - derived angiogenic
cells.