As the body develops and ages, the number and type of
stem cells changes.
The new technique could also be useful in understanding how
stem cells change oxidation properties during differentiation into other cell types.
This suggests that Drosophila neural
stem cells changed minimally during the fly's evolution from its ancestors, which did not undergo metamorphosis.
It has long been known that the neural
stem cells change as the human brain develops and ages.
«Watching
stem cells change provides clues to fighting osteoporosis in older women.»
Endogenous Fluorescence Signatures in Living Pluripotent
Stem Cells Change with Loss of Potency.
«Bringing together this team, to do this kind of work means we will be better able to understand how
stem cells change as they grow and become different kinds of cells.
Not exact matches
This provides a game
changing advantage in regenerative medicine that otherwise relied on the concept of
stem cells.
Whether it is
changing text books to teach religion as a «science,» making laws that prohibit
stem -
cell research which would without question help those in need, to stopping of any kind of gay rights, trying to put religion (christianity) into schools, a woman's right to choose, etc, etc...
That balance has
changed considerably in the past few years, as alternative avenues of
stem -
cell science have opened up and it increasingly seems like whatever therapeutic potential such
cells may someday have could be explored and achieved without the destruction of embryos.
The
stem -
cell breakthroughs haven't
changed any of this» they illustrate it.
The recent news that the promise of
stem cell research can be pursued without using human embryos has permanently and dramatically
changed the
stem cell debate.
If detected early,
stem cell transplants can
change babies» lives.
He added: «The important thing is that you work with people who are like - minded and interested in pursuing the same sort of things where you can, and we will, whether the subject is
stem cell or whether the subject is climate
change.»
Scientists must seek a new, more energetic engagement with Americans if they are to overcome public skepticism on issues ranging from climate
change to
stem cell research, AAAS CEO Alan I. Leshner writes in a commentary in The Chronicle of Higher Education.
When Stein eliminated Nampt from neural
stem cells, several significant
changes took place.
Famous for: Uses
stem cells to grow human bone - potentially
changing how surgeries are performed.
When compared to other religious groups, Evangelicals have often been more wary of science as evidenced in debates about evolution,
stem cell research, and climate
change.
«Look at all the issues — climate
change,
stem cell research, general environmental issues, health care, energy — that all have a fundamental scientific or engineering basis.
The essays represent a wide range of scientific topics: neuroscience, biology, «Big Data», forensic anthropology, science policy,
STEM education, wildlife ecology, environmental sustainability, sociology, medicine, global health, science ethics, stem cell research, materials engineering, crowd - sourcing, computer science, biotechnology, genetics, agricultural sciences, climate change, and information technol
STEM education, wildlife ecology, environmental sustainability, sociology, medicine, global health, science ethics,
stem cell research, materials engineering, crowd - sourcing, computer science, biotechnology, genetics, agricultural sciences, climate change, and information technol
stem cell research, materials engineering, crowd - sourcing, computer science, biotechnology, genetics, agricultural sciences, climate
change, and information technology.
Faced with an often - hostile Congress, Obama enacted many of his signature policies by executive order — from reversing restrictions on research with human embryonic
stem cells to helping communities prepare for climate
change.
PhD funding by the University's Institute for Life Sciences for Catarina kick - started the collaboration between Richard and Rahul at the Institute for Developmental Sciences and us, which otherwise might have been difficult, that has led to exciting results, some stunning images and insight that has the potential to
change people's lives using
stem cell therapy.»
The project's goals were to explore and describe the range of epigenetic
changes that take place in bone marrow as
stem cells develop into different types of mature blood
cell.
As the heart starts pumping a primitive blood - like fluid around the body of an embryo, the
change in pressure from the flowing liquid is the cue for
cells lining the aorta to
change first into blood
stem cells, then into all blood -
cell types in the body.
Using a mathematical model known as the Ising model, invented to describe phase transitions in statistical physics, such as how a substance
changes from liquid to gas, the Johns Hopkins researchers calculated the probability distribution of methylation along the genome in several different human
cell types, including normal and cancerous colon, lung and liver
cells, as well as brain, skin, blood and embryonic
stem cells.
«This study signals a big
change in thinking, because it provides simple and efficient tools for scientists to study
stem cell creation in a stage - by - stage manner.
Researchers at the Université libre de Bruxelles, ULB define for the first time the
changes in the
stem cell dynamics that contribute to wound healing.
Using human fetal «mini-brains» grown in 3 - D cultures, scientists determined that a specific protein produced by the Zika virus
changes the properties of neural
stem cells in the developing brain of an infected fetus, potentially causing microcephaly in newborns (Ki - Jun Yoon, abstract 103.06, see attached summary).
The creation of the Centre of Regenerative Medicine in Barcelona (CMRB) reflects «a
change in the Spanish public policy regarding derivation and use of human embryonic
stem cells (HESC), based on a progressive evolution of the public awareness and sensibility of the Spanish [citizenry],» says CMRB Director Juan Carlos Izpisúa Belmonte in an e-mail.
Targeting exhausted immune
cells may
change the prognosis for patients with acute myeloid leukemia (AML) relapse after a
stem cell transplant, according to Penn State College of Medicine researchers.
Analyzing tissue specimens from 10 people with stomach cancer, the researchers found evidence that those same mature
cells in the stomach also had reverted to a
stem cell - like state and had begun to
change and divide rapidly.
An update search enlarged the pool of study data, but did not
change the content of the conclusion of the benefit assessment of
stem cell transplantation (SCT) for multiple myeloma conducted in 2012.
«
Stem cell transplantation for multiple myeloma: New data did not
change conclusion.»
They found similar
changes in gene expression in the same genes with increased activity of glucose transporters in both the
stem cells and the fat
cells, Sen noted.
Sen and his colleagues tested sucralose, a popular low - calorie sweetener, on
stem cells —
cells that could
change into mature fat, muscle, cartilage or bone
cells — taken from human fat tissue.
«There's so much unknown about [
stem cells], you permanently
change the boundaries of biology by working in such a field,» Hochedlinger says.
«Disturbances to these processes may cause neuronal
stem cells to develop into different types of
cells or may cause neurons to migrate to different locations in the brain,
changing neuronal circuitry and potentially leading to behavioral disorders like schizophrenia.»
How sleep apnea is related to these conditions is debated, but Cavadas and her co-authors propose that prolonged disruptions in blood oxygen levels and sleep fragmentation can generate
stem cell exhaustion, epigenetic
changes, increased inflammation, and other hallmarks of aging.
In addition, the KDM4 inhibitor induces a
change of the molecular make - up of the cancer
stem cells and drives them out of stemness.
Contributions from careful, sober - minded scientists can also help defuse controversy in fields that get headlines, such as climate
change and embryonic
stem cells.
If prenatal
stem cell therapy proves successful and safe, ethicists and other physicians agree, it could be life -
changing.
Some may
stem directly from how the altered digestive system works — secreting different levels of hormones, for example — or
changes in nerve
cells that communicate with the gut.
«Unfortunately, these
stem cell manipulations can lead to permanent genetic
changes which would make them unsafe to use especially as a potential sperm or egg,» he says.
Although many scientists doubt that Orlic's bone - marrow
stem cells actually morphed directly into new heart tissue, they do believe the
cells may have secreted powerful chemical cues — growth factors — or perhaps
changed into blood vessels that revitalized the hearts.
Now comes a first rate example of how CRISPR is
changing the pace of biomedical research by linking up with another cutting edge technology — human pluripotent
stem cells (hPSCs).
Stem cells are immature blood
cells and, in theory, introducing the gene into them should produce a permanent
change in that individual's maturing blood
cells.
Although transcription factors are often the ingredients scientists use to induce
stem cell fate, Dalby and Ulijn hypothesize that certain metabolites «fuel» the pathways that result in variable concentrations of transcription factors that drive these
changes.
The researchers found that the blond hair commonly seen in Northern Europeans is caused by a single
change in the DNA that regulates the expression of a gene that encodes a protein called KITLG, also known as
stem cell factor.
They also plan to evolve the chemistry behind the materials so that it may be possible for gels to better mimic more complex cellular environments beyond the control of stiffness alone, as well as investigate how dynamic
changes in matrix properties — a hallmark of the
stem cell niche — can be mimicked in the laboratory.
Stem cells from umbilical cord blood are highly prized for their ability to
change into the
cells of other tissues.