Sentences with phrase «stem cells controlling»

Using newly discovered information, the researchers made significant advances in developing a family of drug candidates that target a receptor known as peroxisome proliferator - activated receptors gamma (PPARγ), a key regulator of stem cells controlling bone formation and bone resorption and a master regulator of fat.

«Neural stem cells control their own fate.»

Several pint - size projects are in development, including gene chips, protein arrays, stem cell controls and electronic circuits.

Different model organisms like the fruit fly Drosophila melanogaster are used for their research, aimed at decoding the principles of stem cell control with the aim to also apply them to higher forms of life and eventually humans.

Not exact matches

Look to birth control, gay marriage, abortion, and embryonic stem cell research if you need examples.

What do the Seer Stones of the Mormon faith say about stem cell research or a woman's access to birth control?

(i) a woman's right to choose; (ii) teaching evolution in school; (iii) medical immunization of teen girls against HPV; (iv) assisted suicide; (v) gay marriage; (vi) my right to view art and theatre deemed «offensive,» «blasphemous» or «obscene» by theists (vii) basic $ ex education for older school children; (viii) treating drug abuse as principally a medical issue; (xi) population control; (x) buying alcohol on a Sunday; (xi) use of condoms and other contraceptives (xii) stem cell research.

In the middle east under Islam: There's no abortions, birth control, gay marriage or stem cell research.

(i) a woman's right to an abortion; (iii) medical immunization of teen girls (and boys) against HPV; (iv) assisted suicide; (vi) gay marriage; (vii) my right to view art and theatre deemed «offensive,» «blasphemous» or «obscene» Catholics; (viii) basic $ ex education for older school children; (ix) treating drug abuse as principally a medical issue; (x) population control; (xi) buying alcohol on a Sunday in many places; (xii) use of condoms and other contraceptives; (xiii) embryonic stem cell research; (xiv) little 10 year - old boys joining organizations such as the Boy Scouts of America, regardless of the religious views of their parents; and (xv) gays being allowed to serve openly in the military.

No abortions, birth control, gay rights, divorce or stem cell research.

Scientists have long speculated that astrocytes, the cell type that controls many neuronal functions, give rise to neural stem cells in damaged brain tissue.

The scientists also discovered that the stem cells released tiny packets of microRNA, bits of genetic material that control how genes function.

Researchers from the Department of Biomedicine at the University of Basel have now found that the fate of adult hippocampal stem cells is not only controlled by their local niche, but also by a cell - intrinsic mechanism.

Now, a research team at Lund University in Sweden has uncovered a completely new mechanism that controls how proteins are produced to direct stem cell function.

To make stem cells the basis for safe medical treatments, however, the field would need the ability to tightly control stem cell pluripotency, the ability to become many cell types, and self - renewal or immortality, the ability to keep dividing and multiplying over time in constant turnover.

The current view proposes that stem cell differentiation is controlled by their local environment, the so - called niche.

A key protein controls stem cell properties that could make them more useful in regenerative medicine, according to a study led by Mount Sinai researchers and published in the journal Cell Stem Cstem cell properties that could make them more useful in regenerative medicine, according to a study led by Mount Sinai researchers and published in the journal Cell Stem Ccell properties that could make them more useful in regenerative medicine, according to a study led by Mount Sinai researchers and published in the journal Cell Stem CCell Stem CStem CellCell.

«Our work illustrates that this exquisite control mechanism — regulated by PUS7 and pseudouridine — is critical to adjusting the amount of proteins needed for human stem cells to grow and produce blood,» says Cristian Bellodi.

There is evidence to suggest the gene originally controlled stem cells or immune response, and was only later co-opted to defend animals against rogue cells when they became large and long - lived.

Setton says the multistep process her lab used to derive NP - type cells from the hiPSCs provides the necessary quality control as scientists seek additional uses for stem cell therapies.

The investigators found that when LIF - treated muscle stem cells were transplanted to skeletal muscle, they formed two to three times more muscle fibers as control cells did.

In addition, the healed bones resulting from stem cell treatment were found to be significantly stronger and able to withstand more stress than those in the control group.

«We have identified a code of «molecular switches» that control a very aggressive subpopulation of brain cancer cells, so - called glioblastoma stem cells,» says Mario Suvà, MD, PhD, of the MGH Department of Pathology and Center for Cancer Research, co-lead author of the Cell article.

Instead mice injected with stem cells developed a far greater number of synapses, or connections between neurons, at the damaged site than control mice did.

If we can boost the immune system and allow microglia to do their job and control brain tumor stem cells, it would be like removing the seed from the soil — stopping the tumor growth before it starts to get out of control.»

They showed that ZIKV infection of cortical progenitors (stem cells for cortical neurons) controlling neurogenesis triggers a stress in the endoplasmic reticulum (where some of the cellular proteins and lipids are synthetized) in the embryonic brain, inducing signals in response to incorrect protein con - formation (referred to as «unfolded protein response»).

«In pancreatic, ovarian and liver cancers, we hope that by adding anti-cancer stem cell drugs to standard of care, we can control proliferating cells within the tumor that could otherwise help the tumor regenerate in the face of existing chemotherapies.»

Varghese and her team showed that they could control the differentiation of human pluripotent stem cells into functional osteoblasts — bone - building cells — simply by adding the molecule adenosine to their growth medium.

There have also been safety concerns confronting all hESC studies, including worries that the embryonic stem cells could proliferate out of control.

The kit includes a pocket 3 - D printer, stem cell starter and tabletop lidded meatbox to ensure the shmeat grows in a temperature - and humidity - controlled environment.

Once stem cells can be grown and differentiated in a controlled way to replace degenerated cells and repair tissues, medical science may then be able to diagnose and cure many intractable diseases at their earliest stages, such as type 1 diabetes, Parkinson's disease, various cardiovascular diseases, liver disease, and cancer.

«The ability to control autoimmunity by autologous HSCT [hematopoietic stem cell transplantation] has been demonstrated in other treatment - refractory autoimmune conditions, including neurologic diseases.

They also plan to evolve the chemistry behind the materials so that it may be possible for gels to better mimic more complex cellular environments beyond the control of stiffness alone, as well as investigate how dynamic changes in matrix properties — a hallmark of the stem cell niche — can be mimicked in the laboratory.

Since Yamanaka's breakthrough, dozens of groups have reported other ways of reprogramming cells as well as techniques to control differentiation of stem cells into neurons, cardiovascular cells, and other tissues of interest for regenerative medicine.

The study, «VlincRNAs controlled by retroviral elements are a hallmark of pluripotency and cancer» found that novel non-coding parts of the human genome known as vlincRNAs (very long intergenic, non-coding RNAs) triggered by ancient viruses, participate in the biology of stem cells, and in the development of cancer.

The researchers performed a literature search of MEDLINE, EMBASE and PsycINFO databases and also manually searched reference lists for original, randomized, controlled trials on animals that examined the association between IVD stem cell transplant and the change of disc height.

The team's next step is to zoom in on the molecular mechanisms that control how the Wnt signaling pathway interacts with the nail stem cells to influence bone and nail growth.

By examining the cell cultivation dishes, the researchers were able to observe how the patients» cells behaved and developed from stem cells to nerve cells and compare them with cells from healthy controls.

«A large number of quiescent hematopoietic stem cells was activated simultaneously when the epigenetic control provided by genomic imprinting was removed,» explains Venkatraman.

Searching for a way to help people regain control over their unreliable bladders, Anthony Atala, a urologist at Children's Hospital Boston, injected stem cells from the limb muscles of rats into their deliberately damaged urinary sphincters, which control flow.

Based on anatomy and molecular markers, we propose that it arose by duplication of a neighboring stem cell, which may have enabled finer neuronal control over leg - related behaviors, such as walking and grooming.»

«TGF - beta functions as an important time signal that controls when a stem cell should stop producing one type of nerve cell and instead start producing another, while also gradually limiting the stem cell's future development capacity,» says Johan Ericson, Professor of Developmental Biology, who led the study.

First, it is impossible to control their makeup from batch to batch, which can cause stem cells to behave inconsistently.

One clinician who has not waited for controlled clinical studies is California osteopath David Steenblock, who offers stem cell therapy for more than 20 diseases, including Alzheimer's, traumatic brain injury, Parkinson's, arthritis, stroke, and heart disease.

Scientists at Columbia's Zuckerman Institute have uncovered new insights into how stem cells transform into brain cells that control leg movements.

The findings, published today in Nature, demonstrate that these myeloproliferative neoplasias only appear after damage to the microenvironment that sustains and controls the hematopoietic stem cells — the cells that produce the cells of the blood and the immune system.

There is no question that ability to generate glucose - responsive, human beta cells through controlled differentiation of stem cells will accelerate the development of new therapeutics.

«In normal conditions, the microenvironment is able to control the proliferation, differentiation and migration of the hematopoietic stem cell.

Dr. Melendez said, «What was really interesting for us was to think that the growth of stem cells can be controlled by distant cells.

The researchers traced stem cells as they matured into motor neurons, which are the type of nerve cells that control muscle movement.