Sentences with phrase «stem cells in culture»

Spike and Gray grew the mammary stem cells in culture dishes and stained them so that new stem cells appeared a different color from differentiated mammary cells.

Engineering a megakaryocyte niche (a special environment in which stem cells live and renew) that supports the growth of hematopoietic stem cells in culture, is the next step for the researchers.

The work was led by Dan S. Kaufman, a hematologist, and James A. Thomson, the first scientist to grow human embryonic stem cells in culture.

Moving forward, he was able to place these taste stem cells in a culture dish and prompt them to grow into the different mature taste cell types, thus creating a taste bud in a dish — scientifically known as taste organoids.

Zheng, together with Leah Boyer, then a researcher in Gage's lab and now director of Salk's Stem Cell Core, generated diseased neurons by taking skin cells from patients with Leigh syndrome, reprogramming them into stem cells in culture and then coaxing them to develop into brain cells in a dish.

Under experimental conditions, the researchers then demonstrated that elevated levels of elastase dramatically reduce the survival and operation of muscle stem cells in culture.

Not exact matches

Animal cells are cultured from stem cells and incubated in a «bioreactor» into tissue that can be «harvested» and formed into familiar foods like meatballs, patties, and fish sticks.

In both cases individual members may exercise some dominance over others, in particular by altering the patterns guiding further growth and development, but the social coordination stems from basic patterns embodied in the genetic makeup of the plant cells and in the laws and traditions of human culturIn both cases individual members may exercise some dominance over others, in particular by altering the patterns guiding further growth and development, but the social coordination stems from basic patterns embodied in the genetic makeup of the plant cells and in the laws and traditions of human culturin particular by altering the patterns guiding further growth and development, but the social coordination stems from basic patterns embodied in the genetic makeup of the plant cells and in the laws and traditions of human culturin the genetic makeup of the plant cells and in the laws and traditions of human culturin the laws and traditions of human culture.

In 2010, researchers from the University of Michigan Comprehensive Cancer Center published a study in the journal Clinical Cancer Research showing that sulforaphane had the ability to kill breast cancer stem cells in mice and in lab cultures, and it also prevented the growth of new tumor cellIn 2010, researchers from the University of Michigan Comprehensive Cancer Center published a study in the journal Clinical Cancer Research showing that sulforaphane had the ability to kill breast cancer stem cells in mice and in lab cultures, and it also prevented the growth of new tumor cellin the journal Clinical Cancer Research showing that sulforaphane had the ability to kill breast cancer stem cells in mice and in lab cultures, and it also prevented the growth of new tumor cellin mice and in lab cultures, and it also prevented the growth of new tumor cellin lab cultures, and it also prevented the growth of new tumor cells.

While scientists have previously had success in 3D printing a range of human stem cell cultures developed from bone marrow or skin cells, a team from Scotland's Heriot - Watt University claims to be the first to print the more delicate, yet more flexible, human embryonic stem cells (hESCs).

The next step, Silber says, will be harvesting stem cells from around a «spermless» man's testicles, introducing them into cultures where the cells multiply, and then reimplanting those cells in the man's testicles, which then nurture them into fully mature sperm - producers.

Culturing stem cells by day, and audiences in dingy stand - up clubs by night, it wasn't until Helen Pilcher left the lab that she started basing her comedy on science.

The process is painstaking and involves the systematic «knockout» — removal — of relevant genes in stem cell cultures.

Using human fetal «mini-brains» grown in 3 - D cultures, scientists determined that a specific protein produced by the Zika virus changes the properties of neural stem cells in the developing brain of an infected fetus, potentially causing microcephaly in newborns (Ki - Jun Yoon, abstract 103.06, see attached summary).

In a series of experiments, the researchers first identified a set of 19 transcription factors that were expressed at significantly greater levels in cultured human glioblastoma stem cells capable of tumor propagation than in differentiated tumor cellIn a series of experiments, the researchers first identified a set of 19 transcription factors that were expressed at significantly greater levels in cultured human glioblastoma stem cells capable of tumor propagation than in differentiated tumor cellin cultured human glioblastoma stem cells capable of tumor propagation than in differentiated tumor cellin differentiated tumor cells.

As a graduate student at Princeton University, Moshe Pritsker tried in vain to grow a culture of embryonic stem cells from instructions laid out in the methods section of a journal article.

In 2011, researchers led by David Baker, a computational biologist at the University of Washington in Seattle, created a designer protein that binds HA's stem, which prevented viral infection in cell cultureIn 2011, researchers led by David Baker, a computational biologist at the University of Washington in Seattle, created a designer protein that binds HA's stem, which prevented viral infection in cell culturein Seattle, created a designer protein that binds HA's stem, which prevented viral infection in cell culturein cell cultures.

The team used human embryonic stem cells — which can transform into any cell of the body — and cultured them in a mixture of chemicals to grow human brain cells.

Despite a lack of rigorous clinical trials to test safety or efficacy, a ban of the treatment by health authorities, and a lack of peer review by the scientific community, the privately funded Stamina Foundation has been using cultured mesenchymal stem cells that have been exposed to putative conditions that favour neuronal differentiation to treat different diseases in severely or terminally ill patients.

In collaboration with Ding, the lab of Olivier Voinnet at the Swiss Federal Institute of Technology in Zurich also reported in an accompanying paper the detection of viral siRNAs in cultured mouse embryonic stem cells infected by the Encephalomyocarditis viruIn collaboration with Ding, the lab of Olivier Voinnet at the Swiss Federal Institute of Technology in Zurich also reported in an accompanying paper the detection of viral siRNAs in cultured mouse embryonic stem cells infected by the Encephalomyocarditis viruin Zurich also reported in an accompanying paper the detection of viral siRNAs in cultured mouse embryonic stem cells infected by the Encephalomyocarditis viruin an accompanying paper the detection of viral siRNAs in cultured mouse embryonic stem cells infected by the Encephalomyocarditis viruin cultured mouse embryonic stem cells infected by the Encephalomyocarditis virus.

«Most adult stem cells can not be cultured in vitro without differentiation.»

What about the rare stem - like cells generated in cultures of ovarian cells?

By lowering the oxygen in the culture — adding nitrogen to cut it by more than half — the researchers found they could dramatically improve the percentage of stem cells capable of making normal sperm when put back into the testes.

Part of the trouble is the ingredients: Subtle variations in tissue - culture chemicals and Matrigel, or in different stem cell lines and how they are grown first in 2 - D culture, can have a big impact on how the organoids turn out, Novitch says.

The former Speaker — now a leading candidate for the Republican presidential nomination — talked to DISCOVER in 2006 about evolution, stem cells, Washington's two cultures, and why kids should be paid to take science and math.

But boys who haven't been through puberty can only have sperm stem cells removed and frozen in anticipation of technology that could culture the cells and place them back in the testes, where they produce sperm after puberty.

After experimenting with several different cocktails, the researchers hit on a mix that transformed 100 percent of cultured stem cells into those that looked like neurons in under an hour.

In their work, the researchers also show how TGF - beta can be used in stem cell cultures to mass - produce nerve cells which in turn produce the signalling substance serotoniIn their work, the researchers also show how TGF - beta can be used in stem cell cultures to mass - produce nerve cells which in turn produce the signalling substance serotoniin stem cell cultures to mass - produce nerve cells which in turn produce the signalling substance serotoniin turn produce the signalling substance serotonin.

At the time, culturing stem cells was notoriously hard, but after combing through previous lab experiments, another postdoc in Clevers's lab, Toshiro Sato, concocted a mix of growth factors that coaxed the gut stem cells to replicate in a dish.

Prior research with cultured tissue had shown that a mix of chemicals could change bone marrow stem cells from mice to those resembling brain cells, but when a team led by neurologist Lorraine Iacovitti of Thomas Jefferson University in Philadelphia tried the same brew on human cells, the number altered was modest.

Around the same time, Yoshiki Sasai of the RIKEN Center for Developmental Biology in Kobe, Japan, cultured the first brain organoids, starting not with adult stem cells but with embryonic stem cells.

In practice, however, lung cells — especially from older, ill patients — won't grow well enough in culture, but will have to be produced from stem cells or induced pluripotent stem (iPS) cells, she sayIn practice, however, lung cells — especially from older, ill patients — won't grow well enough in culture, but will have to be produced from stem cells or induced pluripotent stem (iPS) cells, she sayin culture, but will have to be produced from stem cells or induced pluripotent stem (iPS) cells, she says.

The team then cultured the cells for several months in a bath of growth - promoting proteins, trying to get the cells to reverse course and become more like stem cells.

Wagers, then a postdoctoral fellow in the Stanford University lab of stem cell biologist Irving Weissman, spent a week in Verfaillie's lab in 2002 trying to learn to culture MAPCs.

In the monkey, when we tried injecting 20 or 30 laboratory - cultured pluripotent stem cells, nothing happened.

«The culture conditions needed to grow various kinds of stem cells can be very tricky,» down to the source of the water, says neural stem cell biologist David Anderson of the California Institute of Technology in Pasadena.

Their stem cells, which can mature into any type of tissue, were isolated and cultured in a dish around dots of gel - like growth medium.

In the new study, the researchers cultured mouse skin - cancer colonies on various 2 - D and 3 - D environments of different shapes and patterns to see if the tumor shape contributes to activation of cancer stem cells, and to see where in the tumor the stem cells appeareIn the new study, the researchers cultured mouse skin - cancer colonies on various 2 - D and 3 - D environments of different shapes and patterns to see if the tumor shape contributes to activation of cancer stem cells, and to see where in the tumor the stem cells appearein the tumor the stem cells appeared.

All it took to make pluripotent stem cells, they reported, was briefly bathing blood cells from newborn mice in a mildly acidic solution and then tweaking the culture conditions.

Scientists at the Institute of Reconstructive Neurobiology at the University of Bonn applied a recent development in stem cell research to tackle this limitation: they grew three - dimensional organoids in the cell culture dish, the structure of which is incredibly similar to that of the human brain.

They then combined these in a dish with testicular cells from newborn mice in various culture conditions — a process that took hundreds of trials, says author Xiao - Yang Zhao, a stem cell biologist now at Southern Medical University in Guangzhou, China.

A new study in Nature Genetics identifies a specific population of pluripotent embryonic stem cells that can reprogram to totipotent - like cells in culture.

She thinks that data from embryos cultured for nearly two weeks in the laboratory will provide more useful information than Egli's stem cell studies.

Changes in chromatin may help reduce unwanted stem cell proliferation and can be achieved by adding drugs to experimental cultures in Petri dishes, Kwan said.

Their method relied on briefly bathing blood cells from newborn mice in a mildly acidic solution and then tweaking culture conditions to produce stem cells.

In a culture of embryonic stem (ES) cells, a small population (around 1 %) spontaneously turns into cells that are similar to the totipotent cells of the 2 - cell stage embryo.

Haruko Obokata of the RIKEN Center for Developmental Biology (CDB) in Kobe, Japan, and colleagues at other Japanese institutions and at Harvard Medical School in Boston reported that simply subjecting blood cells from newborn mice to a moderately acidic environment for 25 minutes and then tweaking culture conditions could generate pluripotent stem cells capable of developing into nearly all of a body's cell types.

To boost their odds, the researchers bathed the cells in culture media that encourage growth of neural stem cells.

Researchers used cultured stem cells derived from their feline patients in the hope of reducing inflammation and promoting tissue regeneration.

«Our stem cells also survive outside of mice, in a culture, so we can also manipulate them in a laboratory,» said Abad, adding that: «The next step is studying if these new stem cells are capable of efficiently generating different tissues such as that of the pancreas, liver or kidney.»