Sentences with phrase «stem cells in the hippocampus»

It was already known that a few weeks after an ECT procedure or after taking an effective antidepressant that stem cells in the hippocampus turn on and make more copies of hippocampal neurons.

Buried deep underneath the folds of the cerebral cortex, neural stem cells in the hippocampus continue to generate new neurons, inciting a struggle between new and old as the new attempts to gain a foothold in memory - forming center of the brain.

Found that the neural stem cells in the hippocampus of AD mice exhibit abnormal development and impaired functional integration.

She showed that neural stem cells in the hippocampus of mice genetically modified to mimic Alzheimer's symptoms develop abnormally and integrate poorly into the network of neural circuits.

Not exact matches

Neural stem cells with the ability to form new neurons in the brain are normally present in the hippocampus (the part of the brain connected to learning and memory) and in the subventricular zone of the brain.

Boldrini surmised that reduced cognitive - emotional resilience in old age may be caused by this smaller pool of neural stem cells, the decline in vascularization, and reduced cell - to - cell connectivity within the hippocampus.

They discovered that the chemicals and radiation used to kill tumor cells damage the stem cell reservoir in the hippocampus and nearly halt the formation of new neurons in both children and adults.

In the hippocampus, a brain region vital for laying down new memories, «stem cells continue to add new circuit elements,» says Stanford University neuroscientist Theo D. Palmer, who helped Monje find out why brain fogginess can persist for years after cancer treatment has ended.

These are neural stem cells in the adult mouse hippocampus.

«In the past it was deemed technically impossible to follow single cell stem cells in the brain over time given the deep localization of the hippocampus in the brain,» said JessbergeIn the past it was deemed technically impossible to follow single cell stem cells in the brain over time given the deep localization of the hippocampus in the brain,» said Jessbergein the brain over time given the deep localization of the hippocampus in the brain,» said Jessbergein the brain,» said Jessberger.

In a new study published in Science, the laboratory of Sebastian Jessberger, professor in the Brain Research Institute of the University of Zurich, has shown for the first time the process by which neural stem cells divide and newborn neurons integrate in the adult mouse hippocampuIn a new study published in Science, the laboratory of Sebastian Jessberger, professor in the Brain Research Institute of the University of Zurich, has shown for the first time the process by which neural stem cells divide and newborn neurons integrate in the adult mouse hippocampuin Science, the laboratory of Sebastian Jessberger, professor in the Brain Research Institute of the University of Zurich, has shown for the first time the process by which neural stem cells divide and newborn neurons integrate in the adult mouse hippocampuin the Brain Research Institute of the University of Zurich, has shown for the first time the process by which neural stem cells divide and newborn neurons integrate in the adult mouse hippocampuin the adult mouse hippocampus.

Neuroscientists Jing Wang and Freda Miller, both then at Toronto's Hospital for Sick Children, showed that when nondiabetic mice are given metformin, their memory improves, thanks to an increase in the neural stem cell population and in the number of these cells that develop into healthy neurons in the hippocampus, the brain's memory center.

Michael Young and colleagues derived neural stem cells from the hippocampus of adult rats and then injected them into the gel - like vitrous of eyes in rats showing retinal degeneration.

Natural neural stem cells — cells that can develop into other brain tissues — are found deep in the brain, in the subventricular zone and hippocampus.

The research team selectively overexpressed a transcription factor, Klf9, only in older neurons in mice, which eliminated more than one - fifth of their dendritic spines, increased the number of new neurons that integrated into the hippocampus circuitry by two-fold, and activated neural stem cells.

The scientists implanted neural stem cells into the hippocampus, which is a brain region involved in making new memories and connecting them to emotions.

«In our study, we found that removing Tet2 from the hippocampal stem cells that give birth to new neurons caused some cognitive impairment, but removing it from the whole hippocampus caused even more.

Boldrini and colleagues think that the deterioration of the brain in old age could be attributed to this smaller pool or neural stem cells, reduced connectivity among cells within the hippocampus and decline in blood vessels.

She and her team now want to determine whether the medial septum - to - hippocampus circuit can be targeted with therapies to protect DG stem cells and restore normal DG neurogenesis in cases where neurogenesis is abnormal.

Song and her team found that in mice, the medial septum - to - hippocampus circuit works to keep DG stem cells in this normal, low - activity state.

«This circuit controls the activity of stem cells in the part of the hippocampus where neurogenesis occurs,» said Song, a member of the UNC Neuroscience Center.

«This medial septum GABA circuit works through the local PV interneurons in the hippocampus to instruct stem cells to become activated or to stay quiet,» Song said.

In the healthy mice, the stem cells migrated throughout the brain, but in the mice with neuronal loss, the cells congregated in the hippocampus, the area of the injurIn the healthy mice, the stem cells migrated throughout the brain, but in the mice with neuronal loss, the cells congregated in the hippocampus, the area of the injurin the mice with neuronal loss, the cells congregated in the hippocampus, the area of the injurin the hippocampus, the area of the injury.

The deletions specifically affected neural stem cells and the new neurons that they form in the hippocampus.

This image from a confocal microscope shows neural stem cells (green) in the mouse hippocampus that are actively proliferating because they express Ki67 (red), a protein that is only present in proliferating cells.

Develops new nerve cells from the stem cells (blank cells) in the hippocampus, which is the part of the brain related to memory and learning.