Not exact matches
In 2010, researchers from the University of Michigan Comprehensive Cancer Center published a study in the journal Clinical Cancer Research showing that sulforaphane had the ability to kill breast cancer stem cells in mice and in lab cultures, and it also prevented the growth of new tumor cell
In 2010, researchers from the University
of Michigan Comprehensive Cancer Center published a study
in the journal Clinical Cancer Research showing that sulforaphane had the ability to kill breast cancer stem cells in mice and in lab cultures, and it also prevented the growth of new tumor cell
in the journal Clinical Cancer Research showing that sulforaphane had the ability to kill breast cancer
stem cells in mice and in lab cultures, and it also prevented the growth of new tumor cell
in mice and
in lab cultures, and it also prevented the growth of new tumor cell
in lab cultures, and it also prevented the growth
of new tumor
cells.
TWO types
of human ear
cell have been grown
in the
lab from fetal
stem cells.
For example, animal studies have shown that neurons derived
in the
lab from human embryonic
stem cells improve Parkinson's symptoms; however, any residual
stem cells associated with those neurons could form masses
of unwanted
cells.
Starting
in 2007,
in the same French Institute
of Health and Medical Research (INSERM)
lab where he did his Ph.D., Catelain worked to harness the potential
of embryonic
stem cells for treating cardiac diseases.
In science news around the world, the U.S. Food and Drug Administration (FDA) cracks down on
stem cell labs, Brazil opens one
of its largest national reserves to gold and iron mining, and the International Atomic Energy Agency launches a global bank for low - enriched uranium.
The two - part approach netted a set
of mutations seen only at relapse that enabled the team to sift and sort leukemic and normal
stem cells using tools developed
in the Dick
lab a few years ago to zero
in on specific
cell types fated to relapse.
Shane Mayack was a postdoc
in the
lab of Amy Wagers at Harvard University's Joslin Diabetes Center, studying blood
stem cells.
Buer Sen, MD, first author
of the
Stem Cells paper and research associate
in Rubin's
lab, used cytochalasin D to break up the actin cytoskeleton.
A former postdoctoral researcher who worked
in the
lab of a promising
stem cell biologist engaged
in scientific misconduct, faking images and other data
in two papers that were later retracted, according to U.S. government investigators.
I couldn't resist composing this after the mention
of the charmingly misspelled word «hematopoetic»
in your story on blood grown
in the
lab from
stem cells (12 November, p 8):
Zheng, together with Leah Boyer, then a researcher
in Gage's
lab and now director
of Salk's
Stem Cell Core, generated diseased neurons by taking skin cells from patients with Leigh syndrome, reprogramming them into stem cells in culture and then coaxing them to develop into brain cells in a d
Stem Cell Core, generated diseased neurons by taking skin
cells from patients with Leigh syndrome, reprogramming them into
stem cells in culture and then coaxing them to develop into brain cells in a d
stem cells in culture and then coaxing them to develop into brain
cells in a dish.
«Our paper is a blueprint
of how the cartilage - producing
cell, called a chondrocyte, is made and maintained by Sox9,» said He, a postdoctoral research associate in the lab of Andy McMahon, director of the Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research at
cell, called a chondrocyte, is made and maintained by Sox9,» said He, a postdoctoral research associate
in the
lab of Andy McMahon, director
of the Eli and Edythe Broad Center for Regenerative Medicine and
Stem Cell Research at
Cell Research at USC.
In collaboration with Ding, the lab of Olivier Voinnet at the Swiss Federal Institute of Technology in Zurich also reported in an accompanying paper the detection of viral siRNAs in cultured mouse embryonic stem cells infected by the Encephalomyocarditis viru
In collaboration with Ding, the
lab of Olivier Voinnet at the Swiss Federal Institute
of Technology
in Zurich also reported in an accompanying paper the detection of viral siRNAs in cultured mouse embryonic stem cells infected by the Encephalomyocarditis viru
in Zurich also reported
in an accompanying paper the detection of viral siRNAs in cultured mouse embryonic stem cells infected by the Encephalomyocarditis viru
in an accompanying paper the detection
of viral siRNAs
in cultured mouse embryonic stem cells infected by the Encephalomyocarditis viru
in cultured mouse embryonic
stem cells infected by the Encephalomyocarditis virus.
Using next - generation sequencing technologies that were previously unavailable, Michael Gardner, a graduate research assistant, and Jianying Wang, a senior research associate
in Mitchum's
lab, made a remarkable new discovery — nematodes possess the ability to produce a second type
of peptide that can effectively «take over» plant
stem cells that are used to create vital pathways for the delivery
of nutrients throughout the plant.
Around 2000, then - postdoc Wagers and other researchers
in Irving Weissman's and Thomas Rando's
labs at Stanford revived the method, known as parabiosis, to study the fate
of blood
stem cells and muscle
cells.
Glioblastomas
in lab dishes and mouse brains are fakes, little Potemkin villages that everyone thought were faithful replicas
of human glioblastomas but which, lacking tumor
stem cells, were nothing
of the kind.
O'Shea, a professor
in the Department
of Cell & Developmental Biology and director
of the U-M Pluripotent
Stem Cell Research
Lab, and McInnis, the Upjohn Woodworth Professor
of Bipolar Disorder and Depression
in the Department
of Psychiatry, are co-senior authors
of the new paper.
More cautious researchers would have realized they were on the wrong track, says Rudolf Jaenisch, a
stem cell researcher at the Massachusetts Institute
of Technology
in Cambridge whose
lab spent 2 months trying to make STAP
cells and contributed data to the new paper.
For the purpose
of additional experiments, the researchers generated myocardial
cells from embryonic
stem cells and human skin
cells,
in collaboration with the
lab headed by Prof Dr Jürgen Hescheler at the University
of Cologne.
Another is that the transplanted bits
of tumor act nothing like cancers
in actual human brains, Fine and colleagues reported
in 2006: Real - life glioblastomas grow and spread and resist treatment because they contain what are called tumor
stem cells, but tumor
stem cells don't grow well
in the
lab, so they don't get transplanted into those mouse brains.
And at that point, he started to think about, you know, the idea
of being able to grow meat from
stem cells or from
cells; to be able to grow meat
in a
lab as opposed to, you know, raising animals
in a farm somewhere; to be able to have a
lab and grow meat anywhere, you know, regardless
of the environmental conditions or other factors.
In 2009, Hans Clevers of the Hubrecht Institute in Utrecht, the Netherlands, announced that his lab unexpectedly created a miniature version of a gut while cultivating adult stem cells that the team had discovered in mouse intestinal tissu
In 2009, Hans Clevers
of the Hubrecht Institute
in Utrecht, the Netherlands, announced that his lab unexpectedly created a miniature version of a gut while cultivating adult stem cells that the team had discovered in mouse intestinal tissu
in Utrecht, the Netherlands, announced that his
lab unexpectedly created a miniature version
of a gut while cultivating adult
stem cells that the team had discovered
in mouse intestinal tissu
in mouse intestinal tissue.
«There have been previous reports
of other
labs deriving beta
cell types from
stem cells, no other group has produced mature beta
cells as suitable for use
in patients,» he said.
Now head
of her own
lab at Stanford, Heilshorn engineers proteins to aid neural
stem cells in healing injured brains and spines.
To save the life a young boy who lost most
of his skin (left, red), researchers took a small bit
of his remaining skin (gray) and grew skin
stem cells in the
lab.
To create different
cell types
in the
lab,
stem cells must be coaxed down the road
of determination — the branching paths that fetal
cells normally travel to become neurons, skin
cells, muscle
cells, or any number
of other
cell types.
Then De Luca and colleagues used a retrovirus to insert a healthy copy
of the LAMB3 gene into DNA
in the
lab - grown skin
stem cells.
In September 2015, the team took a 4 - square - centimeter patch of unblistered skin from the boy's groin and grew skin stem cells in the lab from that sampl
In September 2015, the team took a 4 - square - centimeter patch
of unblistered skin from the boy's groin and grew skin
stem cells in the lab from that sampl
in the
lab from that sample.
Last May
in Nature Neuroscience, his
lab and a team at Columbia University reported that embryonic
stem cells could be used to shed light on the origins
of amyotrophic lateral sclerosis (ALS), the progressive neurodegenerative disease
in which motor neurons
in the brain die.
At the time, culturing
stem cells was notoriously hard, but after combing through previous
lab experiments, another postdoc
in Clevers's
lab, Toshiro Sato, concocted a mix
of growth factors that coaxed the gut
stem cells to replicate
in a dish.
Kevin Eggan's
lab in Cambridge has been busy demonstrating the clinical potential
of the research — and finding novel ways to create
stem cells.
The finding potentially paves the way for scores
of labs to generate new
stem cell lines without cloned embryos, which had long been considered the only realistic way
of making human
stem cells in the short run.
Some basic research findings are being translated into new treatments, and with the discovery
of induced pluripotent
stem cells in 2006, the field has seen a step - change
in biological understanding that will affect the way new drugs are identified and tested and, potentially, the way
cells can be generated
in the
lab.
Several types
of progenitor
stem cells (purple, yellow) were present
in the
lab - grown skin
cells, along with long - lived holoclones (pink).
Stephen DiNardo, PhD, a professor
of Cell and Developmental Biology and Kari F. Lenhart, PhD, a postdoctoral scientist in the DiNardo lab, study the development of fruit fly sperm as a model to investigate the stem cell - ni
Cell and Developmental Biology and Kari F. Lenhart, PhD, a postdoctoral scientist
in the DiNardo
lab, study the development
of fruit fly sperm as a model to investigate the
stem cell - ni
cell - niche.
Using
stem cells from umbilical cord blood, researchers are growing clusters
of real liver
cells in the
lab.
Wagers, then a postdoctoral fellow
in the Stanford University
lab of stem cell biologist Irving Weissman, spent a week
in Verfaillie's
lab in 2002 trying to learn to culture MAPCs.
Specifically, the researchers examined hematopoietic
stem cells that were filmed under the microscope
in the
lab of Timm Schroeder at ETH Zurich.
Researchers realized that they could cut open the top
of the trunks
of their highest - yielding trees, extract
stem cells and grow up clones by the thousands
in lab dishes.
The hamburger was grown
in Post's
lab using bovine skeletal muscle
stem cells, collected from a piece
of fresh beef.
The existence
of cancer
stem cells has already been reported
in a number
of human cancers, explains Professor Jacobsen, but previous findings have remained controversial since the
lab tests used to establish the identity
of cancer
stem cells have been shown to be unreliable and,
in any case, do not reflect the «real situation»
in an intact tumour
in a patient.
The Food and Drug Administration approved the trial
in January 2009 but put it on hold last September because
of safety concerns after
lab animals injected with
stem cells developed small cysts at the injury site.
Thorold Theunissen, a postdoctoral fellow
in Jaenisch's
lab and co-first author
of the study, says «Our work provides a rigorous set
of criteria for comparing naïve human
stem cells to their counterparts
in the early human embryo.
One
of the team's most exciting new observations suggests a link between autism and a type
of neural
stem cell called outer - radial glia (oRGs), discovered by the Kriegstein
lab in 2010.
In 1983, Beddington set up her own lab at Oxford and became one of the first scientists to demonstrate that embryonic stem cells can give rise to any tissue found in a developed bod
In 1983, Beddington set up her own
lab at Oxford and became one
of the first scientists to demonstrate that embryonic
stem cells can give rise to any tissue found
in a developed bod
in a developed body.
The approach enabled a wide range
of studies
of human brain development, including implicating a new class
of neural
stem cell recently discovered by the
lab in the evolutionary expansion
of the human brain and identifying how the mosquito - borne Zika virus may contribute to microcephaly
in infants infected
in utero.
When current methods for generating naïve
stem cells in the
lab were judged using the three tests, each fell short
of mimicking the naïve embryonic
cells in different ways.
The plaintiffs, Piero Anversa and Annarosa Leri, had sued Harvard Medical School and its affiliate, Brigham and Women's Hospital (BWH)
in Boston, claiming that the inquiry into their
lab at BWH wrongfully damaged their professional reputations, derailed the sale
of their
stem cell company, and cost them lucrative job offers.
Several years ago, one
of the students
in Verma's
lab noticed that BRCA1 is very active
in the neuroectoderm, a sliver
of embryonic tissue containing neural
stem cells that divide and differentiate into the brain's vast assortment
of cell types and structures.
To find methods for
stemming the tide
of liver - damaging microbes, Schnabl and team tried experimentally bumping up copies
of the REG3G gene
in intestinal lining
cells grown
in the
lab.