Sentences with phrase «stem cells lines reprogrammed»

Researchers compared induced pluripotent stem cells lines reprogrammed from different adult cell types that have been previously differentiated from embryonic stem cells.

In one study, geneticist Joseph Ecker at the Salk Institute in California took various stem cell lines reprogrammed from skin, fat, and other tissues and examined each line's genome for dna methylation, chemical marks that alter how genes are expressed.

Not exact matches

But just how close adult and reprogrammed stem cells can come to matching the capabilities of embryonic stem cells has become a contentious question in the debate over whether the federal government should continue funding research on embryonic lines.

In one promising approach, cellular reprogramming, stem cells can be generated by fusing adult skin cells with embryonic stem cells from existing cell lines.

As a result, many of the studies published up to now describe only two or three patient stem cell lines,» says David Panchision, who oversees the NIMH's National Cooperative Reprogrammed Cell Research Group (NCRCRG) program, which supported this wcell lines,» says David Panchision, who oversees the NIMH's National Cooperative Reprogrammed Cell Research Group (NCRCRG) program, which supported this wCell Research Group (NCRCRG) program, which supported this work.

If there was one embryonic stem cell, and it differentiated into five distinct specialized cells, and then these specialized cells were reprogrammed into five distinct induced stem cell sets — then at least one of these lines would be similar to an embryonic cell with 95 % confidence.

Although the transferred nucleus isn't adequately reprogrammed to make an animal, it can be tested to see if it functions well enough to make a line of stem cells.

Recent studies have shown how to reprogram adult cells into non-embryonic stem cell lines called induced pluripotent stem cells — «pluripotent» meaning that they could give rise to almost any category of cell.

Frozen but hardly halted, the lines of reprogrammed stem cells in the Massachusetts General Hospital laboratory of biologist Konrad Hochedlinger are preserved in liquid nitrogen at -170 °C.

Reprogramming adult cells to function like embryonic stem cells is one way researchers hope to create patient - specific cell lines to regenerate tissue or to study specific diseases in the laboratory.

The choice of the somatic cell for reprogramming, the reprogramming technology chosen, and the differentiation techniques utilised, all work synergistically towards the production of mature iPSCs - derived chondrocytes which are comparable to patient - derived chondrocytes, in line with Good Manufacturing Practice guidelines for an «off - the - shelf» stem cell product.