Not exact matches
For example,
using 3 - D bioprinters — which can print the structure of human tissue with biodegradable material — and
stem cells, which are
used to populate the 3 - D printed structure,
researchers can grow actually human tissue.
Mr Blair also
used his trip to California to woo
researchers in
stem cell science to come to the UK, after Mr Bush
used his first presidential veto to block the further expansion of federal investment in this area of research.
The
researchers then
used genetic techniques to find out what would happen when NAD manufacturing is turned off in the adult neural
stem cells of the mouse brain.
In a study in the journal Science,
researchers explain how they
used mouse embryonic
stem cells and microchip technology to create heart muscle tissue that actually beats.
Instead, after several days,
researchers harvest embryonic
stem cells, which theoretically can develop into any type of
cell and, according to many
researchers, may someday be
used to treat neurodegenerative diseases or other conditions.
Researchers used stem cells to create retinal pigment epithelium
cells, which were transplanted into a patient's retina (left) in an area depicted by the black circle.
To make the HSCs, the Harvard group
used human skin
cells to create induced pluripotent
stem cells (iPSCs), adult
cells researchers genetically reprogram to an embryonic -
stem -
cell state, where they can grow into any kind of
cell.
A clinic in India says it has
used stem cells to treat Down's syndrome in up to 14 people, but the announcement has alarmed independent
researchers
Researchers at the University of Washington and elsewhere are
using stem cells to trigger the growth of these
cells, which stop regenerating in mammals after birth.
Researchers at Rush University Medical Center are exploring a new therapy
using stem cells to treat spinal cord injuries within the first 14 to 30 days of injury.
Researchers at Geron, meanwhile, had successfully derived neurons from human embryonic
stem cells and were pursuing research that would eventually look to repair the damage caused by spinal - cord injuries, a possible
use for embryonic
stem cells that was much touted at the time.
Across multiple samples
using a stiff matrix, while varying the degree of tethering, the
researchers found no difference in the rate at which
stem cells showed signs of turning into bone - like
cells.
A team of
researchers at the Stanford University School of Medicine has
used a gene - editing tool known as CRISPR to repair the gene that causes sickle
cell disease in human
stem cells, which they say is a key step toward developing a gene therapy for the disorder.
Using a mathematical model known as the Ising model, invented to describe phase transitions in statistical physics, such as how a substance changes from liquid to gas, the Johns Hopkins
researchers calculated the probability distribution of methylation along the genome in several different human
cell types, including normal and cancerous colon, lung and liver
cells, as well as brain, skin, blood and embryonic
stem cells.
In the future the
researchers see
using stem cells taken from patients to grow new bones.
Some of the
researchers at the centre will study the differentiation of
stem cells into other
cell types, one group by
using human embryonic
stem cell biology and another by studying early embryo development.
The
researchers used several measures to determine whether the
stem cells were effective in alleviating neuropathic pain and bladder dysfunction at six months.
Among the many approaches they took, the
researchers generated induced pluripotent
stem cells (iPSCs) from the SCARB1 - deficient person,
used them to create liver
cells, and showed these new
cells had profound reduction in their ability to take up HDL.
The French
researchers hope that
using freshly created blood
cells made from
stem cells could help alleviate those iron buildup concerns.
The
researchers used chemicals to transform these
cells into
cells that were similar to
stem cells.
Researchers, led by Joshua Mayourian at the Icahn School of Medicine at Mount Sinai,
used mathematical modeling to simulate electrical interactions between these
stem cells and heart
cells to develop insight into possible adverse effects, as well as to hypothesize new methods for reducing some potential risks of this therapy.
Realistic
stem cell therapies to replace diseased or damaged tissue may still be years away, but
researchers have uncovered a promising new
use for these undifferentiated
cells: they can be programmed to become patient - specific laboratory models of inherited liver disease.
In a study recently published in the journal Nature Biotechnology, HSCI
researchers at Harvard University and Massachusetts General Hospital (MGH), in collaboration with Boston Children's Hospital and Dana Farber Cancer Institute, have developed a non-toxic transplantation procedure
using antibodies to specifically target blood
stem cells in mice, an approach they hope will make blood
stem cell transplants for these patients far less toxic.
«
Researchers use a single molecule to command
stem cells to build new bone.»
The
researchers reprogrammed the
cells to create induced pluripotent
stem cells in an FDA - compliant facility at the Broad Stem Cell Research Center; the use of this facility is an important step in the process as preclinical research moves toward human clinical tri
stem cells in an FDA - compliant facility at the Broad
Stem Cell Research Center; the use of this facility is an important step in the process as preclinical research moves toward human clinical tri
Stem Cell Research Center; the
use of this facility is an important step in the process as preclinical research moves toward human clinical trials.
The therapeutic
use of
stem cells is a promising area of medicine for the decades ahead and
researchers are examining why
stem cells function in certain types of niches, microenvironments, and pockets of activity.
The
researchers have now reported in the journal Nature that the normal process of blood formation differs from what scientists had previously assumed when
using data from
stem cell transplantations.
By monitoring
stem cell differentiation on gels that mimic the stiffness and nanofibrous structure of biological tissue,
researchers have identified the specific molecules that
stem cells use when selecting bone and cartilage fates.
Mayo Clinic
researchers have found a way to resynchronize cardiac motion following a heart attack
using stem cells.
Using tumor samples from the Women's Healthy Eating and Living clinical trial,
researchers identified
stem - like tumor
cells as being characterized by low levels of the molecule p53 upregulated modulator of apoptosis (PUMA).
An international group of leading
stem cell researchers has issued a statement that specifies concerns about the development and
use of unproven
stem cell therapies.
Rare
stem - like tumor
cells play a critical role in the spread of breast cancer, but a vulnerability in the pathway that powers them offers a strategy to target these
cells using existing drugs before metastatic disease occurs, report University of California San Diego School of Medicine and Moores Cancer Center
researchers.
That message, delivered in two studies published today, is both good news and bad news for
researchers who hope to
use so - called induced pluripotent
stem cells (iPS
cells) to study diseases and perhaps some day treat patients.
The EPSRC - funded study, published in Biomacromolecules and undertaken by University of Bristol
researchers, explored the feasibility of
using natural fibres such as silk and cellulose as
stem cell scaffolds — the matrix to which
stem cells can cling to as they grow.
Instead of
using white blood
cells, the British
researchers, working with a Dutch group, want to take
stem cells from bone marrow and insert the ADA gene into these.
Researchers have developed a new way to study bone disorders and bone growth,
using stem cells from patients afflicted with a rare, genetic bone disease.
Exploiting the same pre-clinical model
used for their studies, the
researchers are testing the efficacy of this kind of drug candidates against cancer
stem cells, and the possibility of identifying combination regimens with standard chemotherapies with minimized toxic effects, with the perspective of their possible application for the treatment of human breast cancer.
Yoshida sees this tool as remarkably simple and something that can be
used by
stem cell researchers studying any organ.
During the last decade, some
researchers have claimed that primordial follicles in adult mouse ovaries turn over and that females
use adult germ - line
stem cells to constantly resupply the follicle pool and sustain ovulation.
And in the third paper, published online today in Science, developmental biologists and
stem cell researchers Hugo Snippert, Arnout Schepers, Hans Clevers, and their colleagues at the Hubrecht Institute in Utrecht, the Netherlands,
used mice with multicolored intestines to look at the kinds of
cells that form intestinal adenomas, a precursor to intestinal cancer.
While American
stem cell researchers were celebrating the final NIH
stem cell guidelines, questions remain, particularly whether the National Institutes of Health will approve existing lines in time for
use with stimulus funds.
Using a nuclear protein expressed in follicle
stem cells (FSCs), the
researchers found that castor, which plays an important role in specifying which types of brain
cells are produced during embryonic development, also helps maintain FSCs throughout the life of the animal.
Stem cell researchers call them «a major step in the right direction,» although some were disappointed that NIH didn't open the door to the
use of embryos created for research purposes — including through somatic
cell nuclear transfer (cloning) and parthenogenesis (from an unfertilized egg).
This ball of
cells contains «pluripotent
stem cells» — blank slates that can be programed into any type of
cell in the body — and
researchers are hoping to
use these
stem cells to treat various conditions, including infertility.
She adds that
researchers may be able to recreate the results
using adult
stem cells or
cells found in wisdom teeth.
The
researchers used the new lab - on - a-chip to study how adult
stem cells in adipose tissue develop into mature fat
cells, conducting their investigations outside the body.
The
researchers, who released their findings in Cancer Prevention Research Journal, published by the American Association of Cancer Research,
used a visualization technique — immunofluorescence — to identify
stem cells in the colon of pigs that were fed either a high calorie diet or a standard diet.
Last January, the House of Representatives voted, 253 to 174, to pass a bill, H.R. 3, that would allow
researchers to
use leftover embryos from in vitro fertilization (IVF) clinics to create new lines of embryonic
stem cells, and in April, the Senate passed its version of the bill.
That fraction might seem low, but it shows that the technique could be
used as a model for therapies that replace beta
cells in people, the
researchers suggest February 18 in
Cell Stem Cell.
Today the brain's serotonin system is already a known target for the treatment of depression, and according to
researchers it should be possible to
use time signals in pharmaceutical development based on
stem cells.