A new study in rats shows that lacing a penis graft with adult
stem cells yields better healing and sexual function than using the graft alone.
However, her research group has not yet identified how to make
stem cells yield entirely dI1 or entirely dI3 cells — perhaps because another signaling pathway is involved, she said.
Not exact matches
Yet the latter form, which is present some eight weeks after fertilization, is not only ethically unacceptable for research but also far too old to
yield embryonic
stem cells.»
During cloning, the adult nucleus is converted to a totipotent state that will then proceed through a clear progression of developmental steps to
yield pluripotent
stem cells at a later time.
The Dolly experiment [which
yielded the first cloned adult mammal, Dolly the sheep, in 1996] prompted people to find ways of taking specialized
cells and transforming them into pluripotent, undifferentiated
stem cells.
That
yield may sound small, but a low percentage is not necessarily discouraging, according to Evan Snyder, a
stem cell researcher at the Burnham Institute for Medical Research in La Jolla, Calif..
A small skin sample from a person with bipolar disorder can
yield stem cells that can be coaxed to become neurons just like those in the brain.
«First
stem cell study of bipolar disorder
yields promising results.»
In the paper, the scientists report that their method produced more than twice the
yield of potential bone - makers (9 percent) compared to their best application of another method: sorting
cells based on surface proteins presumed to indicate that a
cell is a
stem cell (4 percent).
The mini livers are a major advance in
stem cell research because they have
yielded actual functioning
cells.
Researchers realized that they could cut open the top of the trunks of their highest -
yielding trees, extract
stem cells and grow up clones by the thousands in lab dishes.
Twenty percent of the
cells cloned in this way grew into early embryos, called blastocysts, and 5 percent of them
yielded embryonic
stem cells, which is comparable with results obtained from unfertilized eggs.
«We're looking at the genes and gene networks involved in
stem cell proliferation, meristem development and flowering and branching,» said Van Eck, «with the end goal being that maybe genes that we identify in tomato, which is strictly being used as a model, might help us understand what can be done to increase
yield in other crops.»
«This information
yields new insights into how sperm
stem cells function and develop under normal circumstances,» says the study's lead author Bradley Cairns, PhD, senior director of basic science at HCI and professor and chair of oncological sciences at the U of U. «We have built a very important framework we can now use to help us understand what happens when things go wrong, resulting in issues like infertility and cancer in men.»
Just one
yielded a self - reproducing
stem cell line.
«From skin to brain:
Stem cells without genetic modification: Study
yields neural crest
cells from adult skin
cells, and could lead to new treatments for Parkinson's and other brain illnesses.»
Research into
Stem Cells has grown exponentially over the past two decades and has already
yielded successful or promising therapies for a number of diseases.
\ n \ nWhile historically there had been a ban on taxpayer funding of embryonic
stem cell research, there has never been a ban on private funding in this country and many European countries have allowed this type of research for years, but so far none of this research has
yielded a single therapeutic use.
Asked, for instance, whether adult or embryonic
stem cell research had
yielded any therapeutic results, only 23 % of respondents answered correctly that, to date, only adult
stem cells have resulted in treatments for disease.
Almost 40 % of those who claimed some knowledge about the research in the earlier question believed, incorrectly, that embryonic
stem cells had
yielded therapeutic results, compared to only 23 % of those who said they were unfamiliar with the research.
Morphological and immunocytochemical characteristics indicate the
yield of early progenitors and represent a quality control for human mesenchymal
stem cell culturing.
ViaCyte's trial, with just one
stem cell line, has the capacity to
yield an unending amount of insulin - producing beta
cells.)
On the other hand, first clinical trials with drugs designed to target cancer
stem cells are now under way, so far
yielding moderately positive results.
In 2002, the lab proved that transplanting embryonic
stem cells in animal models of Parkinson's disease
yielded functional new dopamine neurons that restored motor function.
A large scale differentiation system combined with metabolomic purification
yields pure and functional cardiomyocytes from human pluripotent
stem cells
But Hanus and other opponents argued that embryonic
stem cells have yet to
yield any breakthrough treatments.
In mice, induced pluripotent
stem cells created from fibroblasts have been reprogrammed to develop into both sperm and egg
cells and have
yielded healthy offspring.
Jaenisch believes they will eventually succeed and points out that the technique could eventually
yield a bountiful supply of custom human embryonic
stem cells for use in therapy.
It is the result of a global survey of the
stem cell community, which
yielded thousands of votes.
«We hope this research will help inform clinicians into congenital defects related to the formation and maintenance of arteries and veins, and may also
yield new strategies that can coax the development of arteries from
stem cells — which may prove useful for treating coronary artery disease.»
While
stem cell research has enormous potential to
yield new therapies for other diseases, in most cases, years of research will be required to identify the diseases that can benefit from
stem cell treatments and to figure out how
stem cells can be used safely and effectively in those contexts.
He was the principal investigator on the project that
yielded 17 new
stem cell lines, paid for completely with private funds.
When a neural
stem cell becomes activated, it begins a process of
cell division that ultimately
yields new neurons that connect to existing brain circuits.
Zinc finger technology is one of the hottest areas now in everything from gene therapy for HIV to increasing crop
yield, to therapeutic protein production, to the great hope for
stem cell therapy.
Ponatinib Extends Survival Over Transplant in Chronic Phase CML: The results of a new study that included patients from the PACE trial and the European Bone Marrow Transplant registry revealed that treatment with ponatinib
yielded better overall survival (OS) compared with allogeneic
stem cell transplantation (allo - SCT) in patients with chronic phase chronic myeloid leukemia (CP - CML) with a T315I mutation.
The advent of human induced pluripotent
stem cells has been heralded as a major breakthrough in the study of pluripotent
stem cells, for these
cells have
yielded fundamental insights into the reprogrammability of somatic
cell fates, but also because of their seemingly great promise in applications, including potential uses in
cell therapy.
Liposuction may
yield more than just a leaner figure — it can potentially produce
stem cells for tissue reconstruction.
Here, authors from Corning Life Sciences describe dissolvable microcarriers as a scalable solution for large - scale expansion and harvest of functional human mesenchymal
stem cells by enabling simplified downstream processing and high -
yield cell recovery.
By studying the genes that control how
stem cells become inflorescences, we are able to manipulate flower production to improve crop
yields.