Sentences with phrase «stem tumor formation»

Not exact matches

By analysing the early steps that precede tumor formation, Alexandra Van Keymeulen and colleagues found that expression of oncogenic Pik3ca reactivates a multilineage differentiation program in adult stem cells that resembles to an immature embryonic state.

They discovered that the chemicals and radiation used to kill tumor cells damage the stem cell reservoir in the hippocampus and nearly halt the formation of new neurons in both children and adults.

MDSCs are immune cells originating from bone marrow stem cells that possess strong immunosuppressive abilities and are known to play a role in tumor formation and metastasis.

However, stem cell - based approaches are costly, time - consuming, and limited by ethical concerns and the risk of tumor formation.

In particular, the absence of iPSC cells rules out the formation of tumors by pluripotent cells in the recipient, a major concern involving stem cell therapy.

Transplanting non-cardiac stem cells also increases the risk for tumor formation, as many of the cells turn into other cell types besides the target heart cells.

These cells, termed cancer stem cells (CSC), are able to both initiate and maintain tumor formation and progression.

All CM members have research interests in basic cancer mechanisms, including the normal functions of oncogenes and tumor suppressor genes; regulators of cell cycle and apoptosis; regulators of angiogenesis and metastasis; and stem cells and blood formation.

Enforced expression of miR - 200c can strongly suppress the tumor formation driven by human BCSCs and the mammary ducts formation by normal mammary stem cells in vivo, suggesting that miR - 200c is a regulator of normal mammary and BCSCs.

6 - shogaol is 10,000 times more effective than increased doses of Taxol at eliminating cancer stem cells, keeping healthy cells alive, and stemming the formation of tumors.