Sentences with phrase «stimulating growth factors»

The best explanation so far, says Henrietta van Praag, a neurobiologist at the National Institute on Aging, is that exercising the heart somehow stimulates growth factors to produce new nerve cells in the brain.

This is accomplished by giving subcutaneous injections of a stem cell stimulating growth factor for five consecutive days.

Not exact matches

Scientists now recognize that intense exercise helps your brain produce brain - derived neutrophic factor, an important protein that helps stimulate the process of neurogenesis, which is the growth of new brain cells.

For example, faster labour force growth will encourage firms to invest not only to meet greater demand but also to equip these additional workers with machines and other capital to raise their productivity.5 The rate of technological progress is also a key factor, since a faster pace of innovation raises the return on each additional unit of capital, stimulating firms to invest more.

Similar to capsaicin, tumor necrosis factor is suspected to both induce and reduce cancer cell growth, and was shown to commit cells to survival when stimulating EGFR transactivation mechanisms, indicating that EGFR could act as a molecular switch determining the antiapoptotic effect of tumor necrosis factor (50).

Epidermal growth factor is a major growth factor that stimulates cell growth.

Transforming growth factor (TGF)-- alpha, TGF - beta, and granulocyte colony - stimulating factor (G - CSF) are also identified in human milk.

Breast milk contains several anti-infective factors such as bile salt stimulated lipase (protecting against amoebic infections) and lactoferrin (which binds to iron and inhibits the growth of intestinal bacteria).

But recent research has linked their long term use to various unwanted effects, including pneumonia, heart attack, and bone fracture, they point out, adding that PPIs are known to stimulate the production of gastrin, a powerful growth factor.

This happens because the loss of blood flow in a vessel causes the local oxygen level to drop, which stimulates local production of vascular endothelial growth factor, or VEGF, a protein which in most tissues causes the growth of new blood vessels to repair damage.

In 1991, Japanese researchers discovered that Lion's Mane contains two novel classes of nerve growth factor — molecules called hericenones and erinacines — that stimulate the differentiation and re-myelination of neurons.

Others include transplanting so - called Schwann cells from peripheral nerves, using growth factors to stimulate nerve growth, and boosting the immune system in the damaged area (New Scientist magazine, 14 August 1999, p 36).

In a healthy mother, this enzyme is activated by hormones like insulin and insulin - growth factors (IGFs), kick - starting a relay race within cells which stimulates nutrient uptake and, as a result, normal growth and metabolic function.

Sargramostim is a form of GM - CSF (granulocyte - macrophage colony - stimulating factor), a natural protein that spurs the growth of white blood cells in the immune system.

In healthy animals, growth hormone stimulates an increase in a second hormone, insulinlike growth factor 1 (IGF - 1), which in turn promotes tissue growth.

Physiologically, the growth factors interact with these proteins to stimulate cell growth in damaged tissues by activation of receptors.

They also found that when under stress from chemotherapy, megakaryocytes signaled fibroblast growth factor 1 (FGF1), to stimulate the proliferation of hematopoietic stem cells.

In addition, cells were stimulated with a growth factor (PDGF) which led to fast cell migration in only one direction lasting for many hours.

During the creation of new blood vessels, the vascular endothelial growth factor (VEGF) protein differentiates stem cells into vascular endothelial cells and stimulates them to create new blood vessels.

Bovine growth hormone is also known to stimulate the production of insulinlike growth factor 1 (IGF1) by the liver; some studies have shown that high levels of IGF1 in the bloodstream may heighten the risk of prostate and breast cancers as well as a woman's chance of conceiving twins.

In addition, substances called growth factors, produced naturally in the brain, were more abundant in key regions on both sides of the brain in optogenetically stimulated, stroke - affected mice than in their unstimulated counterparts.

When stimulated by molecules called fibroblast growth factors, this receptor, known as FGFR3, prevents the cells from maturing and impedes bone formation.

The laser light indirectly activates growth factors, which stimulate stem cells to turn into dentin cells.

Joseph Poole, M.D., Ph.D., of the Emory University School of Medicine, Atlanta, and colleagues studied whether therapy with granulocyte - macrophage colony stimulating factor (GM - CSF), an agent that functions as a white blood cell growth factor, would improve walking performance in patients with symptomatic peripheral artery disease (a form of vascular disease in which there is partial or total blockage of an artery, usually one leading to a leg or arm).

This happens because the loss of blood flow in a blood vessel causes the local oxygen level to drop, which stimulates local production of vascular endothelial growth factor, or VEGF, a protein that in most tissues causes the growth of new blood vessels to repair damage.

Bevacizumab blocks the activity of vascular endothelial growth factor (VEGF), which stimulates angiogenesis.

Molecular cloning of cDNA encoding a murine haematopoietic growth regulator, granulocyte - macrophage colony stimulating factor.

Conditions that stimulate cell growth, such as growth factors and nutrients, activate rDNA transcription, whereas external signals that harm cell growth inhibit transcription.

Cell division was also stimulated with epidermal growth factor (EGF) at 10 ng / ml in a total added volume of 20 ml.

Complementing this work are recent advances at Joslin identifying new islet growth in patients with long - standing type 1 diabetes, as well as identifying potential islet growth factors, which occur in situations of insulin resistance, that could be used to stimulate the growth of the patient's own beta cells.

Drew Pardoll, Glenn Dranoff, Elizabeth Jaffee, Hyam Levitsky, and colleagues conduct preclinical studies showing that a vaccine composed of tumor cells irradiated and genetically modified to produce immune system growth factor GM - CSF (granulocyte - macrophage colony - stimulating factor)-- which would become known as the therapeutic cancer vaccine GVAX — could induce potent, specific, and long - lasting anti-tumor immunity in multiple mouse tumor models.

At first glance, a puzzle emerges: why would a cancer â $ œwantâ $ to induce blood clots? Cancer cells often send out growth factors that stimulate the growth of new blood vessels (angiogenesis).

Some corneas were wounded to determine whether the wounded areas stimulated BrdU (by staining or fluorescence) followed by the synthesis of transforming growth factor beta (TGFβ).

Finally, we demonstrate that treatment of T - 47D cells with epidermal growth factor (EGF), which promotes cell ruffling, stimulates increased accumulation of activated matriptase at the sites of membrane ruffling, suggesting a possible functional role at these sites.

One of these enzymes, cyclooxygenase - 2 (COX - 2), is an inducible enzyme, the biosynthesis of which is stimulated by growth factors, cytokines, and endotoxin, and is inhibited by glucocorticoids.

Role of IL - 17A, IL - 17F, and the IL - 17 receptor in regulating growth - related oncogene - α and granulocyte colony - stimulating factor in bronchial epithelium: implications for airway inflammation in cystic fibrosis.

Epidermal growth factor stimulates human trophoblast cell migration through Rho A and Rho C activation.

During his doctoral and post-doctoral work under the mentorship of Jeffrey Goldberg, MD, PhD, and Larry Benowitz, PhD, Dr. Trakhtenberg discovered (1) how Set - β and PP2A proteins regulate axon growth; (2) the role of serotonin receptor 2C in neurite growth and processing of visual information; and (3) that inhibiting the transcription factor Klf9 acts synergistically with zinc chelation in stimulating axon regeneration.

And some metabolic mutations, which themselves can promote cancer - causing changes in the cell, will be more successful if they're followed by mutations in tyrosine kinases or transcription factors that stimulate cell growth.

It is known as a hematopoietic growth factor or colony stimulating factorand is given by injection under the skin (subcutaneous) or in the vein (intravenous).

These neurotrophic factors stimulate the differentiation, growth and maintenance of developing neurons in addition to the survival of mature neurons, and are key players in synaptic plasticity [55, 56], cognition and memory formation [57 — 62].

In the majority of studies of in vitro maturation (IVM), follicle stimulating hormone (FSH), luteinizing hormone (LH), estradiol and epidermal growth factor (EGF) are used as supplements.

T cells that specifically recognize cancer are isolated from the patient, stimulated with IL - 2 (a growth factor for T cells), expanded into billions of copies, and then replaced into the patient.

This selection of samples excludes possible factors which may stimulate cell growth.

In addition, we found that GBPs stimulate ILP secretion from the insulin - producing cells, either directly or indirectly, thereby increasing insulin and insulin - like growth factor signaling activity throughout the body.

Vascular endothelial growth factor (VEGF) expressed by neural progenitor cells (NPCs)(cyan) stimulates the growth of blood vessels (red) in the mouse embryonic hindbrain, and provides regulatory factors to promote the self - renewal of neural progenitors.

[6] Growth hormone subsequently stimulates the release of hepatic insulin - like growth factor, which is a major anabolic growth factor and a potent mitogen for many neopGrowth hormone subsequently stimulates the release of hepatic insulin - like growth factor, which is a major anabolic growth factor and a potent mitogen for many neopgrowth factor, which is a major anabolic growth factor and a potent mitogen for many neopgrowth factor and a potent mitogen for many neoplasms.

Pollak says the hormone does make people produce more insulin - like growth factor 1, which stimulates cell division as well as an increase in cell size.

However, recent small short - term studies have revealed the visual benefits of eye injections of medications that block a chemical signal that stimulates blood vessel growth, known as vascular endothelial growth factor (VEGF).

The researchers found that, when stimulated by insulin, diabetic fibroblasts produced less of the VEGF (vascular endothelial growth factor) signaling protein, a key player in boosting the growth of blood vessel cells, than normal fibroblasts did.