This external resistance
stimulates skeletal muscle to react and adapt to the stressor.
Whey contains a high concentration of Leu, which
stimulates skeletal muscle protein synthesis (61).
Leucine is one of the three branched - chain amino acids (BCAAs), however it is unique in its ability to
stimulate skeletal muscle protein synthesis which can result in faster muscle growth and strength gains.
A moderate serving of high - quality protein maximally
stimulates skeletal muscle protein synthesis in young and elderly subjects
Not exact matches
In addition, unlike heart
muscle,
skeletal muscles can perform static contractions if they are repeatedly
stimulated at high frequency.
To address the fatigue characteristics of isolated
skeletal muscles, we dissected the fast extensor digitorum longus (EDL) and slow soleus
muscles from anesthetized mice and subjected them to a repeated contraction protocol in which
muscles were
stimulated for 330 ms every second for 6 minutes at a stimulation frequency of 40 Hz.
In vitro experiments in myogenic cells initially suggested that IL - 15 was an anabolic factor for
skeletal muscle, able to
stimulate the accumulation of contractile protein in differentiated myotubes (8 — 10).
Coupling between Myogenesis and Angiogenesis during
Skeletal Muscle Regeneration Is
Stimulated by Restorative Macrophages
In healthy humans,
skeletal muscle accounts for 70 — 80 % of the insulin -
stimulated glucose uptake in vivo (23), and most of the glucose is stored as glycogen (24).
Brehm A, Krssak M, Schmid AI, Nowotny P, Waldhäusl W, Roden M. Increased lipid availability impairs insulin -
stimulated ATP synthesis in human
skeletal muscle.
Immediately following a workout, the blood flow to
skeletal muscles is
stimulated, and the act of working out «opens up»
muscles to function a bit like a sponge — they're primed and ready to absorb nutrients.
This presents a possible mechanism for these observations, owed to the close relationship between
skeletal muscle GLUT - 4 content and maximal insulin -
stimulated glucose transport capacity.55
Testosterone
stimulates growth hormone responses that enhance
skeletal muscle cellular amino acid uptake
When asked to explain why growth hormone is an anabolic hormone rather than a steroid, the answer is that it
stimulates the continual growth of the body's tissues, namely
skeletal and
muscle.
Akt
stimulates glucose uptake, glycogen synthesis, and protein synthesis via Akt / mTOR and Akt / GSK -3 β signaling networks and inhibits apoptosis and protein degradation in
skeletal muscle by inactivating FoxO transcription factors leading to increased lean mass.
Human growth hormone has become known to improve physical potential of individuals by way of
stimulating collagen synthesis inside
skeletal lean
muscle and tendons, increasing
muscle mass strength as well as improving training performance because of this.
Women tend to have 10 - 30 % less hormones that
stimulate muscle growth and men have more
skeletal muscle to begin with.
According to a 2006 study in the Annals of Nutrition and Metabolism, up to 40 hours of total fasting does not
stimulate catabolic processes that lead to
skeletal muscle atrophy.
BCAA's are the direct source of energy for
skeletal muscles and
stimulate the building of protein in your
muscles.
Up to 40 hours of total fasting does not
stimulate catabolic processes and lead to
skeletal muscle atrophy (82).
Human growth hormone has been shown to improve strength by
stimulating collagen synthesis in the
skeletal muscle and tendons.
Leucine facilitates the insulin -
stimulated glucose uptake and insulin signaling in
skeletal muscle cells: involving mTORC1 and mTORC2.
The recent recognition that de novo lipogenesis might have relevance for lipid homeostasis in
skeletal muscle stems from the realization that Sterol regulatory element binding protein - 1c (SREBP - 1c), a member of the family of transcription factors that regulate the expression of genes involved in lipid storage in liver and adipose tissue, is also present in
skeletal muscle at a level close to that observed in the liver, 41,42... [M] ost fascinating are the very recent demonstrations that glucose alone (in the absence of insulin) can
stimulate de novo lipogenesis in
skeletal muscle cells....
One can also entertain the interesting possibility that, in
skeletal muscle, this substrate cycling is also activated in response to other hormones and neurotransmitters (eg, adiponectin, catecholamines) particularly since adiponectin, as well as adrenergic agonists, can also
stimulate AMPK activity, glucose utilization and fatty acid oxidation in
skeletal muscle or adipose tissue.61, 66 — 69 This substrate cycling between de novo lipogenesis and lipid oxidation could therefore constitute a thermogenic effector in
skeletal muscle.
Akt2 Is Essential for the Full Effect of Calorie Restriction on Insulin -
Stimulated Glucose Uptake in
Skeletal Muscle.
Brief calorie restriction increases Akt2 phosphorylation in insulin -
stimulated rat
skeletal muscle.
«If insulin is infused locally into
skeletal muscle at a rate low enough to avoid systemic reductions in plasma amino acids, MPS is
stimulated.
Therefore, it is not surprising to find that the
muscle hypertrophy resulting from strength training was associated with the increases in whole - body insulin sensitivity we observed, because
skeletal muscle constitutes the target tissue where most of the insulin -
stimulated glucose uptake takes place [34].
Leucine supplementation of a low - protein meal increases
skeletal muscle and visceral tissue protein synthesis in neonatal pigs by
stimulating mTOR - dependent translation initiation
Skeletal muscle contraction is
stimulated by the emission of the neurotransmitter acetylcholine (ACh) by the motor neuron, and terminated by acetylcholinesterase (AChE) in the neuromuscular junction (NMJ).