Not exact matches
When asked to explain why growth hormone is an anabolic hormone rather than a steroid, the answer is that it
stimulates the continual growth of the body's
tissues, namely
skeletal and
muscle.
The recent recognition that de novo lipogenesis might have relevance for lipid homeostasis in
skeletal muscle stems from the realization that Sterol regulatory element binding protein - 1c (SREBP - 1c), a member of the family of transcription factors that regulate the expression of genes involved in lipid storage in liver and adipose
tissue, is also present in
skeletal muscle at a level close to that observed in the liver, 41,42... [M] ost fascinating are the very recent demonstrations that glucose alone (in the absence of insulin) can
stimulate de novo lipogenesis in
skeletal muscle cells....
One can also entertain the interesting possibility that, in
skeletal muscle, this substrate cycling is also activated in response to other hormones and neurotransmitters (eg, adiponectin, catecholamines) particularly since adiponectin, as well as adrenergic agonists, can also
stimulate AMPK activity, glucose utilization and fatty acid oxidation in
skeletal muscle or adipose
tissue.61, 66 — 69 This substrate cycling between de novo lipogenesis and lipid oxidation could therefore constitute a thermogenic effector in
skeletal muscle.
Therefore, it is not surprising to find that the
muscle hypertrophy resulting from strength training was associated with the increases in whole - body insulin sensitivity we observed, because
skeletal muscle constitutes the target
tissue where most of the insulin -
stimulated glucose uptake takes place [34].
Leucine supplementation of a low - protein meal increases
skeletal muscle and visceral
tissue protein synthesis in neonatal pigs by
stimulating mTOR - dependent translation initiation