Sentences with phrase «stopped cell proliferation»

A graduate student Anni Nieminen, the first author in the study explains, «In healthy cells dwindling ATP levels signals activation of AMPK, which tells the cells to save energy, for example, by stopping the cell proliferation.

Not exact matches

When researchers suppressed the ARF gene in mole - rat cells during the reprogramming process to iPSCs, the cells stopped proliferation with sign of cellular senescence, while the opposite happens with mouse cells.
«Further research is needed to characterize how we can potentially remove or block this protein to stop the proliferation of leukemia cells
Healthy wound healing has four phases: blood clotting to stop bleeding, inflammation to remove dead and damaged cells, proliferation of new tissue and the remodeling of tissues to be stronger and better organized.
The new findings showed that these analogs of pactamycin largely stopped cancer cell proliferation and growth, causing cells to age and lose their ability to divide and grow.
However, cells with active Myc can not stop the cell cycle engine and we think that the non-stop proliferation of the cells with low ATP content leads to prolonged activation of AMPK and p53.
It is also the first in an emerging class of therapies called «checkpoint blockade,» which enhance the immune system's ability to attack cancer by interfering with immunological checkpoints that slow or stop immune cell activation and proliferation in the presence of tumors or chronic viral infection.
According to Vogelstein, this catalog, which its developers named the «kinome,» constitutes an ideal collection of targets for cancer researchers seeking to stop the uncontrolled proliferation of cancer cells.
Once the immune system is alerted to stop attacking the collagen type II, there seems to be a proliferation of T - suppressor cells.
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