Shinya Yamanaka and Kazutoshi Takahashi (Gladstone Institutes) have discovered that MYC enables cells to be reprogrammed 10 % more efficiently by overcoming a block that
stops cells reprogramming.
Not exact matches
Once blood pH returns to the ideal range, the sensor turns itself off and the
reprogrammed cells stop producing insulin.
That drug
stops the tumour from
reprogramming immune
cells.
When researchers suppressed the ARF gene in mole - rat
cells during the
reprogramming process to iPSCs, the
cells stopped proliferation with sign of cellular senescence, while the opposite happens with mouse
cells.
«It would be a big mistake,» Meissner notes, «to say, «now we can generate these [
reprogrammed]
cells, [so] we have to
stop all human embryonic stem
cell research.»»
Theoretically, once a particular codon — say, TAG — has been removed from a genome, the
cell's protein - making machinery could be
reprogrammed to assign TAG to an amino acid, instead of being a
stop signal.