Systemic bacterial infections such as those caused by Salmonella are highly regulated and complex processes that include sophisticated offensive and defensive
strategies by both pathogen and host that are orchestrated by virulence factors.
Not exact matches
As more reports appear of a grim «post-antibiotic era» ushered in
by the rise of drug - resistant bacteria, a new
strategy for fighting infection is emerging that targets a patient's cells rather than those of the invading
pathogens.
«You can slow the rate of spread of a
pathogen and even deter bugs
by growing multiple varieties that have different genetic
strategies for defending themselves,» says Ted Wilson, director of Texas A & M University's AgriLife Research Center.
Understanding the mechanism
by which maternal pathologies lead to poor IgG transplacental transfer is crucial to devise optimal maternal immunization
strategies to extend the window of infant protection against common neonatal
pathogens during the first year of life.
Our results show that reduction in IL - 22 production
by a bacterial toxin is an excellent
strategy on the part of the
pathogen to establish infection in the host.
By analyzing the molecular aspects of the extensive immune crosstalk between the fungal
pathogen and the human host allows to define novel evasion
strategies and defines new molecules which can serve as useful markers to develop new antifungal compounds and vaccine candidates.