Sentences with phrase «stress signaling pathways»

Cross-talk between Phosphate Starvation and Other Environmental Stress Signaling Pathways in Plants

Effect of Saturated Stearic Acid on MAP Kinase and ER Stress Signaling Pathways during Apoptosis Induction in Human Pancreatic ß - Cells Is Inhibited by Unsaturated Oleic Acid.

Previous research has shown a link between the brain's stress signaling pathways and AD.

Not exact matches

This signaling pathway is dependent on a molecule that plays an important role in bacterial stress response: Guanosine tetraphosphate.

Work spearheaded by professor Vicent Arbona is progressing in the understanding of the signaling pathway of a plant hormone that will make plants more resistant to stress by flooding.

The daf - 2 gene is also part of a signaling pathway that influences how well cells age and cope with stress.

Still unclear is how the methuselah gene mutation makes flies more stress - resistant, but the amino acid sequence of the protein it makes may be part of a signaling pathway that controls how well cells resist or repair these stresses.

Plants perform these regulations mainly by regulating nuclear gene expression and multiple intracellular signaling pathways have been shown to play a role in the genomic response of plants to stress, but the processes are not well understood.

They found that silencing the TOR signalling pathway — activated in many different types of cancer — increased ER stress in the cells.

The scientists could demonstrate the potential of the protein arrays in the context of plant hormone signaling pathways, which, for example, mediate responses to drought stress or against pathogens.

Moreover, large - scale screens in the C. elegans DMD model allowed identifying genetic and pharmacologic suppressors of dystrophin - dependent muscle degeneration; some of them positively impact mitochondrial functions or structure under stress conditions, or are involved in signaling pathways linked to mitochondria, and others are associated to proteostasis pathways such as autophagy, proteasome and Unfolded Protein Response (UPR).

We are in the middle to identifying the signalling pathways required for formation of these stress assemblies as well as their composition.

Role of Cryptococcus neoformans Rho1 GTPases in the PKC1 signaling pathway in response to thermal stress.

In Ames dwarrf, Snell Dwarf mice, Klotho mice, GHKO mice who have little IGF and GH; and live longer than wild - type; we see that indeed insulin and glucose / nutrient / energy pathways (which create oxidative stress through excessive nutrient via elevated glycation blood glucose creating high glycated albumin and hemoglobin), that aging is acted on by IGF through hormones, GFs, GHs, acting on insulin signals, which act on survival genes (DAF / SIRT / FOXO).

Numerous studies have demonstrated activity of these agents against a wide variety of cancers, especially cancer stem cell - like subpopulations, by a host of different mechanisms which comprise inhibition of signaling pathways, of mitochondrial respiration, as well as of cellular stress responses and others.

The discovery eventually led to the uncovering by others of two additional signaling pathways in mammalian cells that, together with Ire1, help maintain equilibrium in the face of stress, averting a host of diseases.

Effect of the IGF - 1 / PTEN / Akt / FoxO signaling pathway in the duodenal mucosa of rats subjected to water immersion and restraint stress.

Certain metabolites, such as fatty acids, ceramides and cholesterol crystals, elicit inflammatory responses through pathogen - sensing signalling pathways, implicating a maladaptation of macrophages and the innate immune system to elevated metabolic stress associated with overnutrition in modern societies.

«They concluded that genetic differences and type of fat in the roundworm diet appears to be associated with longevity, and that the reason roundworms lived longer with MUFA might relate to less oxidative stress, or alteration in signalling pathways at cell level that improved their longevity.

In addition, we have identified signaling pathways that are activated as part of the integrated stress response in response to soluble amyloid - beta and in AD model mice.

Involvement of PI3K / PKG / ERK1 / 2 signaling pathways in cortical neurons to trigger protection by cotreatment of acetyl - L - carnitine and alpha - lipoic acid against HNE - mediated oxidative stress and neurotoxicity: implications for Alzheimer's disease.

When faced with these daily stressors the PUFAs would be a detriment to all aspects of defending the brain / body from said stressors as they disrupt many vital hormonal signalling pathways, damage lipoproteins, make us more sensitive to sunlight, accelerate glycation, and less resistant to social stress.

Some of the most promising candidate genes appear to be those involved in regulatory pathways such as insulin signaling, immunoinflammatory response, stress resistance or cardiovascular function.»

Nrf2 / ARE Signaling Pathway: Key Mediator in Oxidative Stress and Potential Therapeutic Target in ALS.

The Nrf2 - ARE Signalling pathway: promising drug target to combat oxidative stress in neurodegenerative disorders.

Oxidative stress in tissue cells may trigger an inflammatory response by the NF - kappa B nuclear signaling pathway.

ROS are important signaling molecules for a number of different cell signaling pathways, particularly those associated with stress - response, and we are stress - response machines.

An Overview of the Primary Signaling Pathways Related to Exercise, Oxidative Stress and Antioxidant Intake Via Nutritional Habits and Supplementation

Reactive oxygen species trigger cellular responses by activation of stress - responsive mitogen - activated protein kinase (MAPK) signalling pathways.

Chronic interpersonal stress predicts activation of pro- and anti-inflammatory signaling pathways 6 months later