These results are similar to those found in other sustained nurse home visiting studies, 1 14 although the intervention impacted on a broader range of domains of the home environment for this subgroup of women
than has been reported previously.1 An increasing body of evidence from both animal and human studies suggests that
stress in pregnancy has significant impacts on developmental and behavioural outcomes for children.29 While the mental development of children of mothers who were not distressed antenatally in both the intervention and
comparison groups was comparable with the general population, children's development was particularly poor in the distressed subgroup in the absence of the MECSH intervention, suggesting that sustained nurse home visiting may be particularly effective in ameliorating some adverse developmental impacts for children of mothers with antenatal distress.
This finding is hardly surprising in the context of between -
groups comparisons which confirmed that parents of children with ASD without intellectual disability experience much higher levels of
stress than parents of typically developing children.