Consistent with this genetic overlap, Dr. Coyle's recent postmortem study of neuronal morphology in bipolar disorder has shown, for the first time,
structural abnormalities similar to those in schizophrenia.
Additionally, 2013 MRI research from Cummings School of Veterinary Medicine at Tufts University and McLean Imaging Center at McLean Hospital showed that the
structural brain
abnormalities of Doberman pinschers afflicted with canine compulsive disorder (CCD) were
similar to those of humans with OCD.
Recent estimates suggest that as many as 1.9 million children younger than 18 years have a sport - or recreation - related concussion each year in the United States.1 This injury is biomechanically induced, with symptoms resulting from neuronal dysfunction due to functional and neurometabolic alterations rather than gross
structural abnormalities.2 Compared with boys involved in
similar activities, girls experience higher rates of sport - related concussion,3 - 7 report more severe symptoms,8 - 11 demonstrate worse cognitive impairment,8 - 10, 12 and take longer to recover.11 The neural mechanisms behind these postconcussion sex differences are poorly understood but have been attributed to differences in neuroanatomy and physiology, 13 cerebral blood flow, 14 and the female sex hormones estrogen and progesterone.15 - 17