However, it is still unknown where exactly transcription starts and which regularly recurring DNA segments, DNA modifications or
structural modifications of the DNA are required to determine the start of transcription.
In other words, changing the regulation of dopamine or some other compound appears to have the additional effect of
causing structural modifications that also affect how neurons interact.
The low estimate assumes standard tenant improvements within a structure, designed for commercial use, and excludes items such
as structural modifications, site work, energy studies, surveys and / or exterior improvements.
In a common subtype of acute myeloid leukemia, this abnormal activation of such self - renewing genes is apparently caused
by structural modifications of the DNA packaging.
«It demonstrates that
major structural modifications toward birds occurred much earlier in the evolutionary process than previously thought,» Mackovicky asserts.
The prototype of such bis - macrocycles, plerixafor, was used in a recent study as a starting point
for structural modification, in order to identify compounds endowed with a similar antiviral activity and improved pharmacokinetic properties [94].
John Joyal, Ph.D., Head of In Vitro Biology, joined Moderna in 2013, and is responsible for the assessment of mRNA containing chemical and
structural modifications in various cell systems.
Several studies were directed towards the improvement of the antiviral potency and / or the ADME properties of compound 2
through structural modifications [87 - 93].
Cuomo said the Coliseum promised to make «
basic structural modifications» to fit the League's specifications, including improving the facility's ice - making capabilities.
(Invited) Regulating the CO-Reduction Product Distribution by the Atomic -
Level Structural Modification of the Cu Electrode Surface Y. G. Kim, J. H. Baricuatro, A. Javier, and M. P. Soriaga
Starting from tranylcypromine, which shows modest activity as a 5 - HT2C agonist, a series of 1 - aminomethyl -2-phenylcyclopropanes was investigated as 5 - HT2C agonists through
iterative structural modifications.
One explanation is that, whereas site - based management appears to be an easily
implemented structural modification, in reality it requires deep cultural changes in the school and district (Kranyik and Squires 1995).
Beginning with 2014 models, the JX35 was renamed the QX60, and both the Pathfinder and QX60 received side curtain airbag and rear
door structural modifications to improve occupant protection in side impact crashes.
Without simple but
critical structural modifications, the airbag offers no increase in protection and appears to be little more than a marketing ploy to create an impression of additional safety.
Beginning with 2016 models, the RDX was re-engineered with front - end and occupant
compartment structural modifications to improve occupant protection in both small overlap and moderate overlap frontal crashes.
Further structural modifications were made beginning with 2004 models manufactured in January 2004 and later, so these ratings do not apply to the latest models.
A flawless five - star performance during Euro NCAP's crash tests back in 2013 (that's the pre-facelift model, but the revised one hasn't
suffered structural modifications) should put buyers» worries at ease.
Maximum safety: The body of the Golf Cabriolet offers maximum all - round safety thanks to its extremely fast rollover protection system that deploys in milliseconds, a reinforced windscreen frame and numerous
other structural modifications (under body, side panels, sills, back panel, doors).
These simulations provided accurate initial estimations on how the altered weight distribution would affect dynamic performance,
where structural modifications would be required, and how the Range Rover Evoque Convertible could meet the very same engineering standards as existing Range Rover Evoque derivatives.
In this instance, the seller answered no to the question about any known problems with the sewer but answered yes to the question
about structural modifications, alterations, or repairs made without necessary permits or licensed contractors.
We knew from the get - go that this job far exceeded our limits as DIY handy people AND that it would take upwards of a few thousand to work wall removal and
structural modifications into our kitchen reno budget.
Loosening the issue and rating rules, incorporating high - risk pools, allowing sales across state lines, or eliminating federal essential health benefit (EHB) requirements could necessitate changes ranging from minor adjustments to
major structural modifications.
This in turn allows room
for structural modifications to further reduce weight: cylinder heads with thinner walls and an integrated exhaust manifold are 6.6 pounds (3 kg) lighter while the new aluminum - made cylinder block saves another 55.1 pounds (25 kilograms).
«Modifications of the treatment regimens, additional optimization of the delivery methods via the use of hydrogels, and
structural modifications of the compounds via medicinal chemistry could ensure even better results with CDK2 inhibitors in treating hearing loss in humans.»
Chemical or
structural modifications to DNA can switch off genes, and these changes can pass from generation to generation, a phenomenon called epigenesis.
He summarized the findings of his research work as follows: «By demonstrating
this structural modification, we have been able to show that within the liquid phase a «fragile» less - ordered liquid is transformed into a so - called «strong» liquid with a higher degree of order.»
Beginning with 2006 models,
structural modifications were made to improve occupant protection in side impact crashes, and starting with 2008 models, side airbags were made standard.
The Mercury Mariner, introduced in the 2005 model year, also had
the structural modifications.
DBA Urban Construction 1/2001 — Present Construction Manager / General contractor / Owner / Qualifier Designed, created space plan and directed interior renovations,
structural modifications, additions and new construction.
Identify the goals of the DSM - 5 revision process as well as
the structural modifications accompanying that process in order to apply them to day to day clinical practice.
Structural modifications?
Painting or
any structural modifications to the property are not permitted without written permission from the homeowner.
Since the rest of your house sits on the foundation of your basement, you may require
some structural modifications to create the open areas you desire.