Sentences with phrase «structural studies»

The Jaskólski - Wlodawer team was recognized for structural studies on retroviral proteins, which have contributed to the development of new therapies for diseases such as AIDS and leukemia in children.

The Finnish researchers at Jyväskylä have previously used this specific cluster material, for instance, for structural studies of enteroviruses.

How hard are GPCR structural studies?

Researchers at Umeå University show in a new, detailed structural study, published in the journal Nature Communications, how the binding of the signal - sequence triggers a number of structural changes within the SRP particle.

Structural studies suggest a route to improve the performance of rechargeable batteries.

Recent structural studies have revealed much about the structure and function of mammalian AC but have not fully defined its active site or catalytic mechanism.

Structural studies give insight into how a human sodium channel involved in pain perception can be selectively inhibited.

The head of the «Laura Bassi Centre of Optimized Structural Studies» explains: «We determined the structure of α - actinin using a technique called X-ray crystallography.

«Structural studies often appear normal but what we can do better with functional neuroimaging with SPECT is not only pinpoint specific areas of the brain that are unhealthy with low blood flow, but also demonstrate their improvement with successful brain rehabilitation treatments in persons like football players.»

«Previous structural studies of HNF - 4α and related nuclear receptors only revealed smaller, isolated fragments of these proteins,» said Fraydoon Rastinejad, Ph.D., professor in Sanford - Burnham's Diabetes and Obesity Research Center, located at the Institute's Lake Nona campus in Orlando, Fla., and senior author of the study.

Time - resolved structural studies of membrane proteins Thursday 20 May 2010 at 1215 Room 3213, IMBV, Kristine Bonnevies Hus, University of Oslo

There are already plans for a new infrared beamline at the ALS that will increase the capacity and capabilities for infrared chemical studies and also launch infrared - based 3 - D structural studies at the ALS.

Today, the lin - 28 pathway is a main focus in the Sliz laboratory, where structural studies of other components of the pathway are underway.

Because high - resolution structural studies of the human Nav1.7 channel are hindered by the molecules complexity, these researchers exploited a simpler bacterial Nav channel by fusing portions of human Nav1.7 (i.e. VSD4) onto it.

Isolated target proteins and obtained pure samples to enable further structural studies, facilitate antibody generation and enable the creation of binding assays.

The contest is being billed as the world's first nanocar race, and the aim is to get people excited about nanotechnology and molecular machines, says co-organizer Christian Joachim, a chemist who works at the Centre for Materials Elaboration and Structural Studies in Toulouse, where the event will take place.

These approaches identify what proteins are involved in anesthetic action and can be thought of as a way to better define relevant anesthetic targets, which investigators can then focus on for structural studies.

Enable follow - up structural studies by obtaining pure samples after isolating primary proteins.

Maoka T. Recent progress in structural studies of carotenoids in animals and plants.

The study, published by the journal Science via First Release on April 12, paves the way for determining the structures of other functional states of the ATP synthase, which has been the subject of structural studies for decades in labs across the globe.

Holm and others suggest that structural studies of other enzymes should help modelers soon create other enzyme mimics.

Electrophysiology and structural studies were performed on an annexin V variant containing a mutation of glutamic acid - 95 to serine in the center of the pore region.

Structural studies of chromatin so far have only given us a static view of how DNA is organized in cells.

All PLTs have a midterm review, where they give a presentation and are quizzed by Pelham and the heads of LMB's four divisions: cell biology, neurobiology, protein and nucleic acid chemistry, and structural studies.

The aim of this project is to identify how the HOPS tethering complex, which contains the S / M protein Vps33, interacts with vacuolar SNAREs to promote yeast vacuole fusion by a combination of biochemical, biophysical and structural studies.

Related research (Pereira HJ, et al., 2012) used two different lines of evidence to explain the increase in the ratio of anteiso — to iso - branched alkenes that was observed during the transition from early to late stationary phase in M. luteus: structural studies of a key enzyme involved in fatty acid biosynthesis in M. luteus (FabH, or ß - ketoacyl - ACP synthase III) and transcriptional (whole - genome microarray) studies of M. luteus during different growth phases.

Structural studies of the cell wall polysaccharide from Lactococcus lactis UC509.9 — Evgeny Vinogradov — Carbohydrate Research

These samples are useful for both structural studies and ligand binding assays.

Armed with valuable experience in purifying GPCR for structural studies, Granier obtained a tenure track position at INSERM to work in the Institut de Génomique Fonctionnelle in Montpellier.

Structural Studies of Hantaan Virus Battisti AJ, Chu YK, Chipman PR, Kaufmann B, Jonsson CB, and Rossman MG.

Brunger also employs single - molecule fluorescence microscopy methods to complement his structural studies.

Since then, Skordalakes and his colleagues have continued their structural studies on the accessory proteins associated with telomerase that help regulate the enzyme's activities.

«In the future, we hope our structural studies will provide some basis for drug design that might be used to control sleeping sickness in Africa,» says Dong, who has similar goals for his work with toxoplasmosis and malaria parasites.

The last steps of preparing a protein sample for downstream analyses, such as activity assays or structural studies, involve ensuring that the protein is in its native, soluble form, dissolved in the buffer of choice, and at an appropriate concentration.

Yet despite the transformative impact on structural studies, it takes months to produce specifically tailored nanobodies by llama immunization.

De Camilli's colleagues did a structural study and found that E-Syt can dimerize and harbor lipids.

Here, we present the 2.8 Å crystal structure of human CB1 in complex with AM6538, a stabilizing antagonist, synthesized and characterized for this structural study.

12:15 — 12:45 Marta Ferraroni (Uni Firenze) Structural studies on Ring - Cleaving Dioxygenases involved in the degradation of aromatic compounds

We have developed a rapid and efficient cloning process and combined it with a protein microscreening approach to characterize protein suitability for structural studies.

This resource covers Part 5 of the novel and includes character studies, close reading, thematic and structural studies, hot seating, creative writing, group work, peer assessment and DIRT activities, all with a nod to SMSC.