Sentences with phrase «structural studies by»

Enable follow - up structural studies by obtaining pure samples after isolating primary proteins.

The Deaconescu Laboratory focuses on structural studies by X-ray crystallography, small - angle X-ray scattering and electron microscopy of protein - protein and protein - nucleic acid complexes, particularly those involved in DNA repair and transcriptional regulation.

Not exact matches

June 2008 (264 kb PDF file): IMF research summaries on Latin America's external linkages (by Shaun Roache) and on reaping the benefits of structural reforms (by Stephen Tokarick); regional study on the Eastern Caribbean Currency Union (by Paul Cashin and Evridiki Tsounta); listing of visiting scholars at the IMF during March — April 2008; listing of contents of Vol.

Drawing on the large numbers of studies undertaken by people in the aid world and by independent researchers (few of these studies are cited in Lancaster's volume), he points out that the structural reforms have largely failed and the situation continues to deteriorate.

In contrast, the social - science approach seeks structural and cultural contexts for personages in the past by studying the actual behavior of contemporary people with similar social structures, values and human types.

This study radiotracked several species of resident forest birds in the Coto Brus province of southern Costa Rica, now «dominated by sparsely - shaded coffee farms» — recall that in my post on coffee growing in Costa Rica that most farms, including those marketed as «shade» coffee, have few shade trees of only a couple of species, and lack the structural complexity necessary for true biodiversity preservation.

The increased socioeconomic inequalities in breastfeeding observed in the intervention group supports the argument that population intervention strategies could inadvertently exacerbate, rather than mitigate, socioeconomic inequalities, particularly when the intervention aims to change individual behaviours rather than targeting «upstream» structural changes.25 Our results are also compatible with an observational study from Brazil reporting that breastfeeding rates increased first among the socioeconomically better - off, followed by increases among the poor, over a 20 - year period of active breastfeeding promotion campaigns in Brazil.26

A study led by Pilyoung Kim at the Universities of Denver and Yale showed structural changes in the brains of new fathers.

Hein advised that bridges over creeks that crested would be studied by engineers for structural damage.

This hypothesis is supported by studies of comparative morphological and functional anatomy, which are based on the recognition of structural similarities between the basic body plans of the various animal groups.

Now 24, he is a first - year graduate student in the department of cellular and structural biology at the University of Texas Health Science Center in San Antonio (UTHSCSA), where he is studying the role of oxidative damage — the wear and tear inflicted upon the cell by toxic molecules called free radicals — in the aging process.

«We've known for some time that invadopodia are driven by protein filaments called actin,» said study leader Louis Hodgson, Ph.D., assistant professor of anatomy and structural biology at Einstein.

The study, published by the journal Science via First Release on April 12, paves the way for determining the structures of other functional states of the ATP synthase, which has been the subject of structural studies for decades in labs across the globe.

«By using this approach, we first tried identify the structural modules of well - studied proteins by using as input solely their sequence information and using statistical inference methodBy using this approach, we first tried identify the structural modules of well - studied proteins by using as input solely their sequence information and using statistical inference methodby using as input solely their sequence information and using statistical inference methods.

The new study illustrated an innovative technique to find structural details about G protein - coupled receptors (GPCRs), which are targeted by approximately 40 percent of modern medicines.

And it also allows us to look at a lot of proteins and complexes that don't crystallize or don't behave well enough to be studied by the standard structural biology techniques.

A study by Florian Krause from the Donders Institute in Nijmegen shows for the first time that these individual differences have a structural basis in the brain.

A previous study from the MGH team found that injecting B cells into cardiac tissue damaged by a heart attack improved structural and functional recovery in an animal model.

In a study led by Duke Health and published in the journal Alcoholism: Clinical and Experimental Research, scientists demonstrate in rats that a short duration of the drug donepezil can reverse both structural and genetic damage that bouts of alcohol use causes in neurons, or nerve cells, in the young brain.

As detailed in an accompanying guide, NIST Disaster and Failure Studies Data Repository: The Chile Earthquake Database — Ground Motion and Building Performance Data from the 2010 Chile Earthquake — User Manual (NIST GCR 15 - 1008), the new collection contains tabular data on ground motion, damage and structural properties, as well as nearly 25,000 photographs and drawings, for 273 buildings and structures impacted by the 2010 Maule, Chile, quake, and for comparison, their response to the 1985 quake centered offshore of Valparaíso, Chile, 370 kilometers (230 miles) to the north.

Study co-author, experimentalist Peijun Zhang of the University of Pittsburgh, aided this effort by developing a technique to purify the key proteins in the array and combine them in just the right proportions so that they assemble themselves in thin layers — allowing clearer 3 - D EM snapshots of their structural conformations and interactions with each other.

The study has shown that the bacteria helped to synthesize polymers on their own surfaces which not only were different from those made by conventional methods, but which retained a form of «structural memory» of that surface.

The alloys fabricated by the Kyoto University team are much stronger at high temperatures than modern nickel - based superalloys as well as recently developed ultrahigh - temperature structural materials, the researchers report in their study published in the journal Science and Technology of Advanced Materials.

But the technique's most valuable application will likely be using sound to probe the structural properties of objects — studying metal alloys, for instance, by blasting sound at them.

The Fraunhofer Institute for Structural Durability and System Reliability LBF in Darmstadt, Germany has now solved this problem together with the Institute for Textile Technology (ITA) of the RWTH Aachen in the exploratory study «Bastfix,» which is funded by the German Federal Ministry of Education and Research (BMBF).

A study of losses by Lloyd's Register in 1990 pinpointed three factors that contribute to structural failure: stress on the hull caused by inadvertent overloading, physical damage caused to the ship during loading, and corrosion in cargo spaces.

By joining forces with Professor Wim Versées at the VIB research center for structural biology, the scientists were able to figure out the three - dimensional structure of Skywalker, making it possible to study the protein in microscopic detail.

In the study, jointly funded by the National Institute of Mental Health and the United States Department of Veterans Affairs, senior author Mark Miller, also from the National Center for PTSD, and colleagues examined the associations between PTSD, metabolic syndrome, and structural integrity of the brain.

A study published February 7 in Cell Reports suggests that pieces of hydras have structural memory that helps them shape their new body plan according to the pattern inherited by the animal's «skeleton.»

A study led by Dr. Nicholas Harmer, Senior Lecturer in Structural Biochemistry at the University of Exeter, published today in the journal Chemistry and Biology, provides new information about the way bacterial cells build up a defensive sugar coating and how that process can be interrupted.

In two papers published back - to - back in Biotechnology Journal online on November 30, 2016, a Korean research team led by Professor Kyung - Jin Kim at Kyungpook National University and Distinguished Professor Sang Yup Lee at the Korea Advanced Institute of Science and Technology (KAIST) described the crystal structure of PHA synthase from Ralstonia eutropha, the best studied bacterium for PHA production, and reported the structural basis for the detailed molecular mechanisms of PHA biosynthesis.

By studying the connections between skin cells using AFM and other techniques that probe cells at the nanoscale, Sinha and his colleagues report that pathogenic antibodies change structural and functional properties of skin cells in distinct ways.

More importantly, says Greenberg, the BRCC36 - KIAA0157 complex may represent an attractive drug development target for inflammatory diseases — an effort that should be aided immeasurably by the detailed structural information this study provides.

These changes in function, the study authors suggest, might be the cause of the structural problems that arise later by exerting forces on the heart that change its development.

This study, led by Soo Young Kim and performed at the University of Texas at Austin and the University of California, Berkeley, found that such compensation produces structural brain changes at the site of the stroke in rats, limiting recovery of the injured side.

In a study of structural brain connectivity led by the University of Illinois at Chicago and UCLA, those participants with anorexia nervosa who scored lowest on a test measuring their ability to form insight had more connective abnormalities than other patients in brain regions linked to error detection and conflict monitoring as well as self - reflection.

The symposium features presentations by Philippa Marrack and John Kappler talking on the T cell repertoire; William Paul on interleukin 4 as a prototypic immunoregulatory cytokine; Timothy Springer on lymphocyte trafficking; Pamela Bjorkman on structural studies of MHC and MHC - related proteins, and Jack Strominger on peptide presentation by class I and II MHC proteins; Thierry Boon on genes coding for tumor rejection antigens, including the first tumor antigen, MAGE - 1; and Philip Greenberg on the modification of T cells for adoptive therapy by retroviral - mediated gene insertion Since then, the symposia series has attracted leading immunologists in the cancer vaccine and antibody fields, providing them with a comprehensive view of the promises and challenges in the development of cancer immunotherapies.

The new study focused on a class of artificial SAPNs designed by Professor Peter Burkhard, a structural biophysicist at the University of Connecticut.

A highly collaborative study led by Professor Thomas Helleday (Karolinska Institutet / SciLifeLab) has now generated comprehensive data on the individual structural, biochemical and biological properties of 18 human NUDIX proteins, as well as how they relate to and interact with each other.

Throughout the course of this study, the teams compiled an extensive library of experimental and theoretical data including electronic, magnetic, optical, photoelectrochemical, and structural properties, which are now used as feedstock in material genome work and near - term development of superior PEC materials through materials - by - design techniques.

In this study, the minimum structural features of plerixafor required for antiviral activity was defined by sequential replacement and / or deletion of the amino groups within the azamacrocyclic ring systems.

«One of the neat things this study shows,» said Cravatt, «is that even for enzyme classes as well studied as the hydrolases, there may still be hidden members that, presumably by convergent evolution, arrived at that basic enzyme mechanism despite sharing no sequence or structural homology.»

The mice in the study had mutations in a gene called KL2 (for c - kit ligand 2) in their Sertoli cells, cells in the testis that aid in sperm cell development by providing structural support and growth factors.

In fact, a subsequent study conducted by Liu et al. (2015) and published in Nature Communications, contrasts the CARES measurements with those obtained from the 2012 Clean Air for London (ClearfLo) campaign to show that aerosol coatings influence black carbon absorption and the form and structural details of the mixing state may be specific to the source and region where the mixing occurs.

Yet despite the transformative impact on structural studies, it takes months to produce specifically tailored nanobodies by llama immunization.

In general, the editors encourage submission of experimental structural studies that are enriched by an analysis of structure - activity relationships and will not consider studies that solely report structural information unless the structure or analysis is of exceptional and broad interest.

The study, led by Gunnar von Heijne at Stockholm University / SciLifeLab, was published in Nature Structural and Molecular Biology.

Ebstein anomaly is within the diverse spectrum of cardiac morphologies triggered by a sarcomere protein gene defect.Our study provides evidence for a link between structural proteins, cardiomyopathy, and congenital heart malformations (Postma et al., 2011).

Because high - resolution structural studies of the human Nav1.7 channel are hindered by the molecules complexity, these researchers exploited a simpler bacterial Nav channel by fusing portions of human Nav1.7 (i.e. VSD4) onto it.

By studying the coronavirus spike, which is the biggest Class I fusion protein known, researchers found structural similarities between the spike proteins from influenza and HIV.