12:15 — 12:45 Marta Ferraroni (Uni Firenze)
Structural studies on Ring - Cleaving Dioxygenases involved in the degradation of aromatic compounds
After deciphering the crystal structure of the catalytic domain of PHA synthase, in addition to other
structural studies on whole enzyme and related proteins, the research team also performed experiments to elucidate the mechanisms of the enzyme reaction, validating detailed structures, enzyme engineering, and also N - terminal domain studies among others.
Not exact matches
June 2008 (264 kb PDF file): IMF research summaries
on Latin America's external linkages (by Shaun Roache) and
on reaping the benefits of
structural reforms (by Stephen Tokarick); regional
study on the Eastern Caribbean Currency Union (by Paul Cashin and Evridiki Tsounta); listing of visiting scholars at the IMF during March — April 2008; listing of contents of Vol.
Drawing
on the large numbers of
studies undertaken by people in the aid world and by independent researchers (few of these
studies are cited in Lancaster's volume), he points out that the
structural reforms have largely failed and the situation continues to deteriorate.
It may be that the preacher will find the apparent points of some
structural value later
on in preparation but only after his
study has led him to the point the author sought to make.
This
study radiotracked several species of resident forest birds in the Coto Brus province of southern Costa Rica, now «dominated by sparsely - shaded coffee farms» — recall that in my post
on coffee growing in Costa Rica that most farms, including those marketed as «shade» coffee, have few shade trees of only a couple of species, and lack the
structural complexity necessary for true biodiversity preservation.
When an architectural
study showed that the mansion could not handle a third expansion without costly
structural work, the City Council, library board and Park District hammered out a land swap in which the Park District gave the city and library 27,000 square feet of land at Prospect Street near the Elmhurst Art Museum in exchange for 52,000 square feet of land
on the north and south sides of the mansion.
While we certainly do not claim to utter the last word
on the topic, we imagine that the focus will shift away from the big
structural accounts surrounding inequality and democracy to more micro-level
studies of how autocracies actually function.
I don't expect something
on the level of The Power Broker (Robert Caro's
study on the power of Robert Moses) but do point to the processes and laws that supposedly yield power to an strong executive... there is a
structural difference between executive and legislative... within that, personalities play a huge role.
The
study also found that positive selection more often act
on residues adjacent to, rather than directly at, a critical active site of the enzyme, and
on flexible regions rather than
on rigid
structural elements of the protein.
In the first
study to assess the relationship between
structural and functional MRI data in bipolar disorder, Dr. Shantanu Joshi and his colleagues at the University of California, Los Angeles focused
on brain regions that play a role in mood dysregulation in the disorder.
The
study comes at a time when use of electronics is rapidly expanding among this age group and adds to a growing body of evidence suggesting that - because of
structural differences in their eyes - children may be more vulnerable to the impact light has
on sleep and the body clock.
The
study, published in Nature
Structural and Molecular Biology, showed that a combination of genetics and epigenetics — factors that turn genes
on or off — could explain how lactose intolerance develops over time.
The next morning,
study participants were tested again
on the word pairs, this time while undergoing functional and
structural magnetic resonance imaging (fMRI) scans.
This hypothesis is supported by
studies of comparative morphological and functional anatomy, which are based
on the recognition of
structural similarities between the basic body plans of the various animal groups.
This
study is the first, however, that examines
structural analysis and its impact
on disease development.
In particular, I got to
study how ultrahigh - vacuum techniques could shed light
on kinetic,
structural, and electronic mechanisms that govern a catalytic reaction.
The
study, published by the journal Science via First Release
on April 12, paves the way for determining the structures of other functional states of the ATP synthase, which has been the subject of
structural studies for decades in labs across the globe.
Horner and his experienced colleagues — a
structural geologist; a stratigrapher; a taphonomist (one who
studies what happens to animals after they die); paleontologists specializing in vertebrate, mammalian, plant, and mollusk fossils; a molecular paleontologist; and an expert
on paleomagnetism — are surveying all the fauna and flora that existed during the Hell Creek period (and that survived as fossils), the ways they interacted, and how they may have evolved.
Electrophysiology and
structural studies were performed
on an annexin V variant containing a mutation of glutamic acid - 95 to serine in the center of the pore region.
He cautions, however, that more research is needed over a wider range of management and climatic conditions, particularly since
studies of fertilizers» impacts
on soil
structural properties, such as aggregate stability, are currently few.
The report is silent
on the total amount of funding required to
study the changing Arctic, but it suggests a number of
structural changes to funding mechanisms.
«We originally wanted to
study the effects of tidal forces
on small known galaxies and any attending
structural disruptions.
As detailed in an accompanying guide, NIST Disaster and Failure
Studies Data Repository: The Chile Earthquake Database — Ground Motion and Building Performance Data from the 2010 Chile Earthquake — User Manual (NIST GCR 15 - 1008), the new collection contains tabular data
on ground motion, damage and
structural properties, as well as nearly 25,000 photographs and drawings, for 273 buildings and structures impacted by the 2010 Maule, Chile, quake, and for comparison, their response to the 1985 quake centered offshore of Valparaíso, Chile, 370 kilometers (230 miles) to the north.
According to Dan M. Frangopol, the Fazlur R. Khan Endowed Chair of
Structural Engineering and Architecture at Lehigh University and You Dong, Assistant Professor of Structural Engineering at The Hong Kong Polytechnic University, the majority of previous studies have focused on structural performance and loss assessment under h
Structural Engineering and Architecture at Lehigh University and You Dong, Assistant Professor of
Structural Engineering at The Hong Kong Polytechnic University, the majority of previous studies have focused on structural performance and loss assessment under h
Structural Engineering at The Hong Kong Polytechnic University, the majority of previous
studies have focused
on structural performance and loss assessment under h
structural performance and loss assessment under hurricanes.
The
study has shown that the bacteria helped to synthesize polymers
on their own surfaces which not only were different from those made by conventional methods, but which retained a form of «
structural memory» of that surface.
A
study of losses by Lloyd's Register in 1990 pinpointed three factors that contribute to
structural failure: stress
on the hull caused by inadvertent overloading, physical damage caused to the ship during loading, and corrosion in cargo spaces.
Still, Sheehan said neuroscience already is one of the leaders in data sharing and management, with such resources as the NIH - funded National Database for Autism Research; an NIH - Defense Department sponsored data base
on traumatic brain injury; the NIH - funded Neuroimaging Informatics Tools and Resources Clearinghouse (NITRC), which helps researchers to develop, share and collaborate
on software tools for doing functional and
structural imaging
studies of the brain; and the Neuroscience Information Framework, an NIH initiative that makes neuroscience resources - data, materials, and tools - accessible via any computer connected to the Internet.
Eden and her colleagues report
on a new
structural brain imaging
study that shows, in addition to deafness, early language experience — English versus ASL — impacts brain structure.
In two papers published back - to - back in Biotechnology Journal online
on November 30, 2016, a Korean research team led by Professor Kyung - Jin Kim at Kyungpook National University and Distinguished Professor Sang Yup Lee at the Korea Advanced Institute of Science and Technology (KAIST) described the crystal structure of PHA synthase from Ralstonia eutropha, the best
studied bacterium for PHA production, and reported the
structural basis for the detailed molecular mechanisms of PHA biosynthesis.
These changes in function, the
study authors suggest, might be the cause of the
structural problems that arise later by exerting forces
on the heart that change its development.
Biologist Helena Safavi, co-author
on a paper describing the cone snail insulin published September 12 in Nature
Structural & Molecular Biology, says that
studying complex venom cocktails can open doors to new drug discoveries.
This sheds light
on structural and functional
studies of other ZIP proteins involved in a variety of cancers, osteoarthritis and other serious diseases.
Mark Chaisson, a postdoctoral fellow in Eichler's lab and lead author
on the
study, developed the method that made it possible to detect
structural variants at the base pair resolution using this data.
In a
study of
structural brain connectivity led by the University of Illinois at Chicago and UCLA, those participants with anorexia nervosa who scored lowest
on a test measuring their ability to form insight had more connective abnormalities than other patients in brain regions linked to error detection and conflict monitoring as well as self - reflection.
During his time as an undergraduate student, he was a member of two cognitive neuroscience laboratories, where he worked
on research
studies examining how
structural differences in the brain correlate with performance
on cognitive tests.
The symposium features presentations by Philippa Marrack and John Kappler talking
on the T cell repertoire; William Paul
on interleukin 4 as a prototypic immunoregulatory cytokine; Timothy Springer
on lymphocyte trafficking; Pamela Bjorkman
on structural studies of MHC and MHC - related proteins, and Jack Strominger
on peptide presentation by class I and II MHC proteins; Thierry Boon
on genes coding for tumor rejection antigens, including the first tumor antigen, MAGE - 1; and Philip Greenberg
on the modification of T cells for adoptive therapy by retroviral - mediated gene insertion Since then, the symposia series has attracted leading immunologists in the cancer vaccine and antibody fields, providing them with a comprehensive view of the promises and challenges in the development of cancer immunotherapies.
Other recent research areas have included the
structural characterization of lattice - mismatched epitaxial metal films
on oxide substrates for radiation damage
studies, and the development of new complex oxides as high temperature, radiation - resistant piezoelectrics for use in advanced in situ sensors.
The new
study focused
on a class of artificial SAPNs designed by Professor Peter Burkhard, a
structural biophysicist at the University of Connecticut.
With Washington State University since 2002, Dolan
studies dynamic load
on low - rise buildings, dynamic response of light - frame buildings, response of dowel connections dynamic testing of
structural assemblies and numerical modeling of
structural and material response.
In a recently published
study in Science, researchers from Aarhus University, KTH Royal Institute of Technology and Stockholm University at SciLifeLab presented
structural information
on the sodium - potassium pump in its sodium - binding state that is essential for our understanding of illness and for the development of new medicines.
Systematic SAR
studies, focusing
on sequence optimizations, were conducted to identify essential
structural and electrostatic requirements for the activity of FC131.
A highly collaborative
study led by Professor Thomas Helleday (Karolinska Institutet / SciLifeLab) has now generated comprehensive data
on the individual
structural, biochemical and biological properties of 18 human NUDIX proteins, as well as how they relate to and interact with each other.
She moved to Oxford in 2012 to work at the SGC, initially working in Alex Bullock's Growth Factor Signalling group to
study E3 ubiquitin ligase complexes, and subsequently joining Stefan Knapp's kinase team to focus
on kinase
structural biology and inhibitor discovery.
The Deaconescu Laboratory focuses
on structural studies by X-ray crystallography, small - angle X-ray scattering and electron microscopy of protein - protein and protein - nucleic acid complexes, particularly those involved in DNA repair and transcriptional regulation.
The power of 4D - EM to image
structural dynamics
on the scale of a few hundred nanoseconds and allow the switching dynamics to be quantified makes a unique contribution to the
study of nanostructures.
We show how the HapMap resource can guide the design and analysis of genetic association
studies, shed light
on structural variation and recombination, and identify loci that may have been subject to natural selection during human evolution.
The
study is significant as it binds together
structural correlates of plasticity at the microscale with effects
on behavioral performance.
After completing graduate
studies in
structural biology at the University of Toronto, Sliz signed
on to provide computing expertise in the lab of Stephen Harrison and the late Don Wiley at Harvard University.
Yet despite the transformative impact
on structural studies, it takes months to produce specifically tailored nanobodies by llama immunization.