Sentences with phrase «structure of single proteins»

Scientists hope that free - electron lasers will become the next - generation x-ray source for a range of research problemsfrom probing the structure of single proteins to studying so - called warm, dense matter.

Not exact matches

A: I'm working on using solid - state defects in diamonds as magnetic field sensors, with the goal of using them as little nanoscale MRI machines that can study the structure and dynamics of single biological molecules (e.g., proteins).

RAD52 works by forming a large ring structure that binds to single strands of DNA, and similar to many other DNA - binding proteins, it lacks enzymatic activity.

«What's critical with this and what has never been done before is that a single peptide sequence will work against the toxic versions of a number of different amyloid proteins and peptides, regardless of their amino acid sequence or the normal 3 - D structures.»

A high - resolution map of the human cell has been generated — part of the Human Protein Atlas database — that provides the in situ localization of 12,036 human proteins at a single - cell level, covering 30 subcellular structures, and enabling 14 major organelle proteomes to be defined.

When the researchers looked more closely at the structure of the human enzymes, they saw something unusual: many single polypeptide (protein) chains actually contained two enzymes, one of which was embedded in the other.

This pair of «ribbon diagram» images compares the three - dimensional structures of two closely related proteins, determined by X-ray crystallography: (L) the HAP2 protein from the single - celled alga Chlamydomonas reinhardtii and (R) the fusion protein from dengue virus.

The structure reveals how the many single Aβ protein molecules are staggered in layers on top of each other and are arranged into so - called protofilaments.

Now, they've demonstrated that a single amino acid — known by its number along the protein chain, 139 — is the key to this prion protein variant adopting a «human - like» versus a «hamster - like» structure, while another amino acid, 112, governs the structural differences between the human and mouse versions of the protein.

Christopher Jaroniec, professor of chemistry and biochemistry at The Ohio State University, said that the findings highlight the fact that minor alterations in single amino acids can cause profound differences in structure and function among this family of proteins.

Biologists, biochemists and geneticists who need to visualize the anatomical location of cellular structure, proteins / enzymes, mRNA, and reporter genes within whole tissue are among those who can benefit from this innovative product, which can be used with light microscopy, fluorescence microscopy, confocal microscopy and single / multiphoton microscopy.

Professor Gunnar von Heijne at Stockholm University / SciLifeLab received SEK 31 000 000 for a five - year project called» Single - particle cryo - EM studies of membrane protein biogenesis and structure».

A rare, premature aging disease, Hutchinson - Gilford progeria is caused by a single point mutation in the gene encoding lamin A, which forms a protein scaffold on the inner edge of the nucleus that helps maintain chromatin structure and organize nuclear processes such as RNA and DNA synthesis.

Turning their attention to the single - cell level, they mapped more than 12,000 proteins to 30 subcellular structures, in turn defining the proteomes — the complete sets of expressed proteins — of more than a dozen major organelles.

microRNAs (miRNA)-- small, hairpin - like structures of single - stranded RNA molecules that can regulate the expression of protein - coding genes.

May 18, 2011 Errors in protein structure sparked evolution of biological complexity Over four billion years of evolution, plants and animals grew far more complex than their single - celled ancestors.

He applied single - particle negative - stain EM to obtain the first low - resolution structures of a GPCR / G protein complex in different conformations and to help identify the conditions that eventually led to the X-ray structure determination of the complex.

NCBI provides Gene, Online Mendelian Inheritance in Man, the Molecular Modeling Database (3D protein structures), dbSNP (a database of single - nucleotide polymorphisms), the Reference Sequence Collection, a map of the human genome, and a taxonomy browser, and coordinates with the National Cancer Institute to provide the Cancer Genome Anatomy Project.

Whey Protein is not a single element as it is a complex structure made up of several sub fractions.