Sentences with phrase «structure of the abnormal protein»

Howard Hughes Medical Institute researchers have provided the first detailed look at the core structure of the abnormal protein filaments found in at least 20 devastating diseases, ranging from...

Not exact matches

All of these mutations destabilize the protein's normal structure and promote abnormal SOD1 structures.

At the Gladstone, cardiovascular scientist Robert Mahley, working with a team including neuroscientist Yadong Huang, has identified small «corrector» molecules that modify the structure of ApoE4 protein to one more like that of ApoE3, thereby reducing abnormal fragmentation.

It is thought that disease results from the combination of an abnormal gene (causing an abnormal structure of the SAA protein), and also infectious or environmental factors that cause systemic inflammation and so increase the production of this protein in affected cats.