p53 is therefore well -
studied as an oncogene, or a gene that when not functioning normally can contribute to a normal cell becoming cancerous.
Not exact matches
«Our
study identified miR - 182
as a glioblastoma tumor suppressor that reduces the expression of several
oncogenes that promote cancer development,» said senior author of the
study Alexander Stegh, an assistant professor in the Ken and Ruth Davee department of neurology and of medicine at Northwestern University Feinberg School of Medicine.
The three Ras genes found in humans — H - Ras, K - Ras and N - Ras — were among the first to be linked to cancer development, and a new
study led by VCU Massey Cancer Center researcher Paul Dent, Ph.D., has shown the recently approved breast cancer drug neratinib can block the function of Ras
as well
as several other
oncogenes through an unexpected process.
A new Tel Aviv University
study pinpoints the inverse correlation between a known
oncogene — a gene that promotes the development of cancer — and the expression of an oncosuppressor microRNA
as the reason for extended pancreatic cancer survival.
In this
study, researchers identified one microRNA (MIR548K) encoded in this region, and found it was characterized
as a novel
oncogene and functional assays which demonstrated that MIR548K enhances malignant phenotypes of ESCC cells.
Cunningham serves
as vice chair of the American Cancer Society Molecular Genetics and
Oncogenes Study Section.