She wrote her dissertation on pollen sterility in petunias, but she also
studied cell structure, which led her back to animals and a postdoc at the Scripps Research Institute in San Diego, California, where she studied a protein on the ends of actin filaments.
Cellular Studies (CEL): The study of animal cells involving the use of microscopy to
study cell structure and studies investigating activity within cells such as enzyme pathways, cellular biochemistry, and synthesis pathways for DNA, RNA, and protein.
Not exact matches
Studying mice, investigators from Washington University School of Medicine in St. Louis showed that a specific energy source called NAD is important in
cells responsible for maintaining the overall
structure of the brain and for performing complex cognitive functions.
The shared patterns of gene expression in the limbs and phallus are generated in part by a common set of noncoding DNA, also called «elements» or «enhancers,» which act to control gene expression in both of these
structures, argues a
study published October 1 in Developmental
Cell.
He
studies DNA and RNA quadruplexes, nucleic acid
structures that were first visualized via confocal microscopy in fixed, dead
cells.
Sharon joined Anglister's lab for her master's project and Ph.D.,
studying the three - dimensional
structure of a region in the HIV - 1 protein envelope that helps the virus enter human
cells.
Combing the genetic data from a transmission
study in ferrets, a team led by Thomas Friedrich, a professor of pathobiological sciences at the University of Wisconsin - Madison School of Veterinary Medicine, found that during transmission, when one animal is infected by another through sneezing or coughing, the process of natural selection acts strongly on hemagglutinin, the
structure the virus uses to attach to and infect host
cells.
Stuart Hameroff, an anesthesiologist who has spent many years
studying brain functions, has collaborated with renowned Oxford University polymath Roger Penrose on a model that explains consciousness as the result of quantum processes occurring in tiny
structures called microtubules in brain
cells.
In this
study, partial reprogramming of
cells in vitro reduced DNA damage accumulation and restored nuclear
structure.
He says the
structure could also offer a new way of
studying blood stem
cells and how blood disorders arise.
In a new
study published in the journal Development, the KU Leuven researchers show that individual or small groups of
cells from uterus biopsies can be made to grow into three - dimensional
structures that show many of the features of the womb lining, including the ability to produce mucus.
A few microscopic techniques can focus light deep into the intact brains of dead animals to
study its
structure without damaging the axons, but much of this light is scattered away by the fatty lipid membranes that surround individual
cells, making the technique less than perfect.
While mouse models have traditionally been used in
studying the genetic disorder, Deng said the animal model is inadequate because the human brain is more complicated, and much of that complexity arises from astroglia
cells, the star - shaped
cells that play an important role in the physical
structure of the brain as well as in the transmission of nerve impulses.
Researchers
studied the
structure of proteins from one strain of the H7N9 virus that caused the outbreak and tested how strongly one of the proteins bound to molecules on the surfaces of bird and human
cells.
Matteo Boretto, the first author on this
study, commented that «we were very excited to see that we could not only robustly grow and amplify endometrial tissue in a dish, but that the tiny
structures were also able to reproduce normal responses of the endometrium to hormones: oestrogen makes the tissue thicken, progesterone then induces maturation including folding (see picture), and subsequent removal of both hormones mimics the
cell shedding of the menstrual period.»
In another application, the sensor was used to
study how
cells respond to the introduction of extracellular hydrogen peroxide, which produces a wave of oxidation as it moves through the cellular
structures.
Holographic, phase contrast or differential interference contrast (DIC) miscroscopes have been implemented especially for making «visible,» otherwise «invisible,» transparent objects, opening a new pathway towards the
study and characterization of relevant
structures such as biological
cells or protein layers.
In a previous
study, Professor Schmidt - Ott and his team discovered that it regulates the differentiation of epithelial
cells — they line the cavities and surfaces of
structures throughout the body — in the mouse embryo.
The teams are currently working on the fabrication of 3D
structures from the blend suitable for implantation in patient joints with future
studies focusing on understanding the peculiar interactions between the blend and stem
cells towards refining the quality of regenerated cartilage.
The brittlestar Ophiocoma wendtii, a relative of starfish, can scan the sea floor, thanks to light - sensitive
cells scattered across its skin, rather than by using eye - like
structures, a
study suggests.
Even short - term blockages of this kind can lead to remarkable changes in the auditory system, altering the behavior and
structure of nerve
cells that relay information from the ear to the brain, according to a new University at Buffalo
study.
Such
studies used DNA from mitochrondria —
structures inside
cells — and placed that time of the most recent common ancestor between 99,000 and 148,000 years ago.
The researchers chose to focus on the
cell - division machinery,
studying the meiotic spindle, the
structure composed of microtubules that attaches to chromosomes, pulling them to opposite sides of a
cell before it divides.
A new
study published in eLife and headed by Jordi Casanova and Sofía J. Araújo, both scientists at the Institute for Research in Biomedicine (IRB Barcelona) and the Instituto de Biología Molecular de Barcelona (IBMB - CSIC), describes a
cell communication mechanism that allows the organisation of the extracellular matrix and how this
structure affects
cells through a feedback system.
A new
study shows that these
cells alter their behavior and
structure when the animals» hearing is blocked.
«Investigators create complex kidney
structures from human stem
cells derived from adults: New technique offers model for
studying disease, progress toward
cell therapy.»
The method has allowed researchers to
study key players involved in
cell division — which include proteins that form much of the
structure of chromosomes, and fragments of DNA that help to orchestrate the process.
And by creating personalized organoids from the reprogrammed
cells of patients, scientists could
study disease in a very individualized way — or maybe even use organoid
structures to replace certain damaged tissues, such as in the liver or spinal cord.
By providing a first look at the
structure of the protein complex that includes FGF23 and its co-receptors, the FGF receptor and a-Klotho, the most recent
study challenges the long - accepted belief that only the
cell - attached form of aKlotho can serve as a receptor for FGF23 and hence that FGF23 action is restricted to tissues having the
cell - attached form.
The SOFC, referred to as a third - generation fuel
cell, has been intensively
studied since it has a simple
structure and no problems with corrosion or loss of the electrolyte.
While researchers at the Georgia Institute of Technology don't have a specific application for the doughnut - shaped droplets yet, they believe the novel
structures offer opportunities to
study many interesting problems, from looking at the properties of ordered materials within these confined spaces to
studying how geometry affects how
cells behave.
For this
study, researchers
studied four solar
cells with different selenium contents — and corresponding changes in crystal
structure — and learned that the one with the highest level of selenium did not perform well.
«We know that other animals use polarisation patterns in the sky, and we have at least some idea how they do it: bees have specially - adapted photoreceptors in their eyes, and birds, fish, amphibians and reptiles all have cone
cell structures in their eyes which may help them to detect polarisation,» says Dr Richard Holland of Queen's University Belfast, co-author of the
study.
In the mouse
study, the insulin - producing
cells were placed under the kidney capsule — a thin membrane layer that surrounds the kidney — where they developed into an organ - like
structure with its own blood supply.
The
study suggests that the bacteria and archaea developed completely different
cell membrane
structures and proton pumps, whilst keeping the same machinery for powering growth.
For example, antibody
studies showed that it is located in the Golgi apparatus and endosomes, two
structures within
cells in which b - amyloid is known to be cleaved from its large precursor protein.
«We now have clues to how that double - ring
structure stably lingers until the
cell enters the DNA - synthesis phase much later on in replication,» said
study coauthor Christian Speck of Imperial College, London.
Microscopic anatomy is the
study of minute anatomical
structures assisted with microscopes, which includes histology (the
study of the organization of tissues), and cytology (the
study of
cells).
One of the most intriguing reasons for
studying endosymbionts like Tremblayais to learn about the evolution of mitochondria and chloroplasts, membrane - bound
structures within
cells that produce energy.
Nathans is a neuroscientist who
studies how
cells in the retina — the light - absorbing
structure at the back of the eye, which is considered part of the brain — assume their correct identities, and how those
cells respond to injury and disease.
This
study shows how these issues have been overcome with a newly developed imaging system, making it possible to image
structures as small as 80nm or less anywhere in the
cell.
Scientists have developed new fluorescent probes that prove the existence of
cell membrane
structures called «lipid rafts», allowing researchers to
study how toxins and viruses invade
cells.
«Now we are going back to
studying the
structure of the genome because we realize that the three - dimensional architecture of DNA will tell us how
cells actually use the information.
In the
study, scientists coaxed stem
cells into forming a fully three - dimensional tissue
structure.
Researchers from the University of Michigan and the Mayo Clinic
studied rat IEC - 6 intestinal epithelial
cells, chosen because they maintain a stable diploid genomic
structure (two sets of chromosomes), lack the cellular characteristics of cancer
cells, and replicate normally.
What's more, the resolution — the highest so far in these types of
studies — was good enough to discriminate
structures as small as individual
cells.
The main result of our
study is a detailed description of the
cell reaggregation process dynamics, and also of the
structure of multicellular aggregates of the marine sponges belonging to the Demospongiae class,» explains Andrey Lavrov.
The case for the all - conquering Africans is based mainly on
studies of the Y chromosome and the mitochondrion, an energy - generating
structure within the
cell that has its own small genome and passes down the female line.
«Originally, I was interested in isolating these sodium channels from
cells to
study their
structure,» said Seok - Yong Lee, assistant professor of biochemistry in the Duke University Medical School and principal investigator of the
study.
These
studies show that the DNA found inside mitochondria, the cellular
structures whose job is to provide
cells with energy, is particularly vulnerable, most probably because they handle oxidative chemical reactions.