Sentences with phrase «studied in lab neurons»

The researchers focused on a process — known as «homeostatic scaling down» — that has been well - studied in lab neurons but not before in living animals.

Not exact matches

To study how the fruit fly neurons responded to external temperature, Yadlapalli worked with Chang Jiang, a postdoctoral researcher in the labs of Pramod Reddy and Edgar Meyhofer of the U-M Department of Mechanical Engineering.

Europe came through: Last year, Cory received a European Molecular Biology Organization (EMBO) Installation Grant for his lab in mitochondrial biogenesis, and Gülayşe won a Marie Curie International Reintegration Grant from the European Commission to study how single genes can yield different protein products in neurons.

In a 2016 study, for example, Dokholyan's lab found evidence that «trimer» structures made of just three copies of the SOD1 protein are toxic to the type of neuron affected in ALIn a 2016 study, for example, Dokholyan's lab found evidence that «trimer» structures made of just three copies of the SOD1 protein are toxic to the type of neuron affected in ALin ALS.

For the new study, Dokholyan's team, including lead author Cheng Zhu, PhD, a postdoctoral researcher in his lab, conducted complicated experiments to compare how trimers affect neurons to how larger fibrils affect neurons.

For example, animal studies have shown that neurons derived in the lab from human embryonic stem cells improve Parkinson's symptoms; however, any residual stem cells associated with those neurons could form masses of unwanted cells.

In a recent study published in the Journal of Neuroscience, Michele Noonan, a University of Texas neuroscience graduate student in the lab of Amelia Eisch, shows that a lack of neurogenesis, or birth of new neurons, in the adult rat can actually cause drug addictioIn a recent study published in the Journal of Neuroscience, Michele Noonan, a University of Texas neuroscience graduate student in the lab of Amelia Eisch, shows that a lack of neurogenesis, or birth of new neurons, in the adult rat can actually cause drug addictioin the Journal of Neuroscience, Michele Noonan, a University of Texas neuroscience graduate student in the lab of Amelia Eisch, shows that a lack of neurogenesis, or birth of new neurons, in the adult rat can actually cause drug addictioin the lab of Amelia Eisch, shows that a lack of neurogenesis, or birth of new neurons, in the adult rat can actually cause drug addictioin the adult rat can actually cause drug addiction.

The study's lead author, Toni - Lee Sterley, a postdoctoral associate in Bains» lab said, «What was remarkable was that CRH neurons from the partners, who were not themselves exposed to an actual stress, showed changes that were identical to those we measured in the stressed mice.»

The study also includes three co-first authors: Qingjian Han from Ji's group who discovered SHANK3 in sensory neurons and pain defects in SHANK3 mutant mice; Yong Ho Kim, an electrophysiologist in Ji's group who found diminished TRPV1 function in SHANK3 mutant mice; and Xiaoming Wang from Jiang's lab who generated SHANK3 mutant mice.

But recent studies in both humans and lab mice have suggested that motor neurons in the brain — the upper motor neurons — may be involved in disease progression, although the extent and significance of this involvement has remained unknown.

«That suggests these neurons are providing a copy of the motor command directly to the auditory system,» said David M. Schneider, Ph.D., co-lead author of the study and a postdoctoral fellow in Mooney's lab.

This week in the JCI, a study conducted by David Engblom's lab at Linköping University in Sweden has demonstrated that the aversive effects of inflammatory pain are driven by prostaglandin signaling specifically on serotonin - producing neurons in the brainstem.

Now, a preclinical study, from the lab of Olivier Berton, PhD, an assistant professor in the department of Psychiatry, in collaboration with Sheryl Beck, PhD, a professor in the department of Anesthesiology at Children's Hospital of Philadelphia, found that bullying and other social stresses triggered symptoms of depression in mice by activating GABA neurons, in a never - before - seen direct relationship between social stimuli and this neural circuitry.

In another study of mice injected with GDF11, postdoc Lida Katsimpardi and others in the lab of Harvard neuroscientist Lee Rubin found that GDF11 also encourages growth of new blood vessels and olfactory neurons in the mouse braiIn another study of mice injected with GDF11, postdoc Lida Katsimpardi and others in the lab of Harvard neuroscientist Lee Rubin found that GDF11 also encourages growth of new blood vessels and olfactory neurons in the mouse braiin the lab of Harvard neuroscientist Lee Rubin found that GDF11 also encourages growth of new blood vessels and olfactory neurons in the mouse braiin the mouse brain.

Studies of individual neurons in dishes of cultured neurons and in brain slices by co-first author Robert E. Stanley, a graduate student in the lab, revealed that neurons in the mutant mice had decreased numbers of dendritic spines, an important part of the synapses that neurons use to communicate with one another.

In a study published in the journal Neuron, co-first authors Christian Burgess, PhD, a postdoctoral fellow; Rohan Ramesh, a graduate student, and colleagues in Andermann's lab recorded images of brain activity in mice across different states of hunger and satietIn a study published in the journal Neuron, co-first authors Christian Burgess, PhD, a postdoctoral fellow; Rohan Ramesh, a graduate student, and colleagues in Andermann's lab recorded images of brain activity in mice across different states of hunger and satietin the journal Neuron, co-first authors Christian Burgess, PhD, a postdoctoral fellow; Rohan Ramesh, a graduate student, and colleagues in Andermann's lab recorded images of brain activity in mice across different states of hunger and satietin Andermann's lab recorded images of brain activity in mice across different states of hunger and satietin mice across different states of hunger and satiety.

Researchers from Hiroki Taniguchi's lab at the Max Planck Florida Institute for Neuroscience (MPFI) published a study in eNeuro in May 2017 showing for the first time that a unique type of inhibitory interneuron called chandelier cells — which are implicated in several diseases affecting the brain such as schizophrenia and epilepsy — seem to develop their connections differently than other types of neurons.

As a graduate student in James Townsel's lab, he studied the regulation and function of choline receptors, which are responsible for the transport of cholinergic neurons.

Previous studies from George's lab had shown that nicotine activates certain «reward» neurons in the brain — giving positive reinforcement to keep smoking.

Indeed, after many years of studies on mirror neurons and their functioning we are shifting our lab research to the study of the control mechanisms in the brain for mirror neurons.

The combination of signals — microRNAs miR - 9 and miR - 124 plus transcription factors ISL1 and LHX3 — tells the cell to fold up the genetic instructions for making skin and unfurl the instructions for making motor neurons, according to Yoo and the study's co-first authors, Daniel G. Abernathy and Matthew J. McCoy, doctoral students in Yoo's lab; and Woo Kyung Kim, PhD, a postdoctoral research associate.

In a study published today (Aug. 4, 2016) in Cell Reports, senior author Chapman, first author Bomba - Warczak and colleagues present clear evidence that toxin is moving between neurons in a lab disIn a study published today (Aug. 4, 2016) in Cell Reports, senior author Chapman, first author Bomba - Warczak and colleagues present clear evidence that toxin is moving between neurons in a lab disin Cell Reports, senior author Chapman, first author Bomba - Warczak and colleagues present clear evidence that toxin is moving between neurons in a lab disin a lab dish.

The technique makes it possible to study motor neurons of the human central nervous system in the lab.

These manipulations, belonging to optogenetics — a technique extensively studied in Yizhar's lab — enabled the researchers to activate only those amygdala neurons that interact with the cortex, and then to map out the cortical neurons that receive input from these light - sensitive neurons.

This is achieved by neurons in a very old part of the brain, the brainstem, according to a study by Carmen Birchmeier's lab at the Max Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC).

Now, in this study, the Wernig lab found that the BAM combination induces degeneration of neurons that use the transmitter glutamate and, to a lesser extent, GABA.

In their study «D - Serine and Serine Racemase are Localized to Neurons in the Adult Mouse and Human Forebrain,» the lab utilized SR deficient (SR - / --RRB- mice, which have < 15 % of normal D - serine levels, to validate and optimize a D - serine immunohistochemical methoIn their study «D - Serine and Serine Racemase are Localized to Neurons in the Adult Mouse and Human Forebrain,» the lab utilized SR deficient (SR - / --RRB- mice, which have < 15 % of normal D - serine levels, to validate and optimize a D - serine immunohistochemical methoin the Adult Mouse and Human Forebrain,» the lab utilized SR deficient (SR - / --RRB- mice, which have < 15 % of normal D - serine levels, to validate and optimize a D - serine immunohistochemical method.

She works in the lab of Dr. Tiago Branco studying how neurons integrate synaptic signals.

«The physical symptoms that affect people with Parkinson's — including tremors and rigidity of movement — are caused by an imbalance between two types of medium spiny neurons in the brain,» said Dr. Kreitzer, whose lab studies how Parkinson's disease affects brain functions.

The lab studies the pathways from sensory input to behavioral output by quantitative analysis of behavior under well - defined conditions, genetic manipulation of animals or individual neuronal cells, and calcium imaging from neurons in living animals.

The Vetter lab is studying glaucoma at the molecular level to understand how genetics influence and determine the fate of neurons in the retina and central nervous system.

However, in a 2014 study, Dr. Sulzer's lab demonstrated that dopamine neurons (those affected by Parkinson's disease) are vulnerable because they have proteins on the cell surface that help the immune system recognize foreign substances.

For example, a study conducted in his own lab found that forebrain assembloids generated from patients with Timothy syndrome — a genetic disease associated with autism and epilepsy, showed abnormal migration of GABAergic neurons during the development of the cerebral cortex.

«It's really amazing that a change in nutrient intake can have such dramatic influences on neuron activity on such a short time scale,» said the study's co-lead author Grant Kauwe, PhD, a postdoctoral research fellow in the Haghighi lab.

In fact, in one study, a dose of mercury sufficient to kill 1 percent of lab rats (lethal dose «LD01»), when combined with a dose of lead sufficient to kill 1 percent, killed 100 percent of the rats.13 A similar test involving mercury and aluminum in cultured neurons killed 60 percent of the cells when the two low - dose toxicants (LD01) were combined.14 Even antibiotics have been shown to enhance the uptake, retention and toxicity of mercury.14 Additionally, testosterone appears to aggravate mercury toxicity during development, while estrogen protects against it.15 This may explain why more boys than girls are diagnosed with autism spectrum disorders and attention deficit disorderIn fact, in one study, a dose of mercury sufficient to kill 1 percent of lab rats (lethal dose «LD01»), when combined with a dose of lead sufficient to kill 1 percent, killed 100 percent of the rats.13 A similar test involving mercury and aluminum in cultured neurons killed 60 percent of the cells when the two low - dose toxicants (LD01) were combined.14 Even antibiotics have been shown to enhance the uptake, retention and toxicity of mercury.14 Additionally, testosterone appears to aggravate mercury toxicity during development, while estrogen protects against it.15 This may explain why more boys than girls are diagnosed with autism spectrum disorders and attention deficit disorderin one study, a dose of mercury sufficient to kill 1 percent of lab rats (lethal dose «LD01»), when combined with a dose of lead sufficient to kill 1 percent, killed 100 percent of the rats.13 A similar test involving mercury and aluminum in cultured neurons killed 60 percent of the cells when the two low - dose toxicants (LD01) were combined.14 Even antibiotics have been shown to enhance the uptake, retention and toxicity of mercury.14 Additionally, testosterone appears to aggravate mercury toxicity during development, while estrogen protects against it.15 This may explain why more boys than girls are diagnosed with autism spectrum disorders and attention deficit disorderin cultured neurons killed 60 percent of the cells when the two low - dose toxicants (LD01) were combined.14 Even antibiotics have been shown to enhance the uptake, retention and toxicity of mercury.14 Additionally, testosterone appears to aggravate mercury toxicity during development, while estrogen protects against it.15 This may explain why more boys than girls are diagnosed with autism spectrum disorders and attention deficit disorders.

In the lab I was studying why an excess of stress hormones had adverse consequences for health (in particular, damaging neurons), while with the baboons, I wanted to understand what social factors predicted who secreted more or less of those stress hormoneIn the lab I was studying why an excess of stress hormones had adverse consequences for health (in particular, damaging neurons), while with the baboons, I wanted to understand what social factors predicted who secreted more or less of those stress hormonein particular, damaging neurons), while with the baboons, I wanted to understand what social factors predicted who secreted more or less of those stress hormones.