Sentences with phrase «studied nucleic acids»

The find highlights how ancient viruses can more easily be identified by their proteins than their more commonly studied nucleic acids, such as DNA or RNA.

DNA repair is a hugely important topic and these three were the first to describe the repair mechanisms,» Thomas Carell, who studies nucleic acid chemistry at Ludwig Maximilians University in Munich, told Science.

Not exact matches

He studies DNA and RNA quadruplexes, nucleic acid structures that were first visualized via confocal microscopy in fixed, dead cells.

In the study, which was published in the journal Nucleic Acids Research, the biologists utilised so - called riboswitches, also called RNA switches, and RNA thermometers.

The study results revolve around the relationship between TET2 and cytosine, one of the four nucleic acid «letters» that comprise the DNA code in genes.

Published Jan. 21 in the journal Nucleic Acids Research, this study describes a complementary set of distinct and portable safeguards capable of securing a wide range of organisms.

Nucleic acid and protein sequences, as well as three - dimensional structures of proteins, are frequently the objects of study, but gene expression as well as the simulation of pathways and biochemical networks are attracting more and more attention.

Dr Ciro Chiappini, first author of the study from the Department of Materials, added: «If we can harness the power of nucleic acids and prompt them to carry out specific tasks, it will give us a way to regenerate lost function.

I had decided to pursue a Ph.D. studying the physical properties of nucleic acids and had won admission to UD, with a teaching assistantship.

«As long as there are sufficient nucleic acids preserved in the specimen, there is really no limit,» says Alison Devault, a researcher at McMaster University studying ancient cholera.

In the study published in Nucleic Acids Research, the researchers were able to induce and inhibit the expression of genes in mammalian cell cultures and were able to regulate intracellular protein levels using light signals.

Attendees at the astrobiology meeting in Arizona showcased an assortment of high - tech devices for next - generation exploration, ranging from microfluidic «life analyzers» and integrated nucleic acid extractors for studying «Martian metagenomics» to exquisitely sensitive, miniaturized organic chemistry labs for spotting tantalizing carbon compounds and minerals at microscopic scales.

Two projects will be done jointly with the Karolinska Institute in Stockholm: Molecular biologist David Baillie of Simon Fraser University in Burnaby, British Columbia, was awarded $ 6.73 million to study protein function in the soil nematode Caenorhabditis elegans, and microbiologist Sherif Abou Elela of the University of Sherbrooke, Quebec, received $ 3.75 million to test modified nucleic acid technologies for determining gene function.

«Recovering nucleic acids from ancient viruses is extremely difficult and plagued by contamination,» notes Angelique Corthals, a forensic anthropologist at the City University of New York in New York City, who was not involved in the study.

The origin of life is not the same as the origin of its constituent building blocks, but laboratory studies on the linking of amino acids into molecules resembling proteins and on the linking of nucleotides into molecules resembling nucleic acids are progressing well.

A University of Colorado Cancer Center study recently published in the top - ranked journal Nucleic Acids Research (NAR) describes a database named multiMiR, the most comprehensive database collecting information about microRNAs and their targets.

Being derived from a sugar containing only four carbons, TNA is structurally the simplest of all potentially natural oligonucleotide - type nucleic acid alternatives studied thus far.

Biochemistry is the study of the structure and function of cellular components, such as proteins, carbohydrates, lipids, nucleic acids, and other biomolecules.

Over the past decade due to the deep - sequencing technologies, we have studied the characterization of nucleic acid alterations in a wide range of cancers generating a large body of information on how cancer develops and evolves.

The insights we expect to gain from this study of mitochondria dysfunction and microRNAs, and what they tell us about how some RPE cells become diseased while neighboring cells are either resistant or susceptible to disease, hold promise of becoming the basis for entirely new therapies for individuals suffering from AMD, built upon nucleic acid - based treatments aimed at rejuvenating RPE cell mitochondria.

The Deaconescu Laboratory focuses on structural studies by X-ray crystallography, small - angle X-ray scattering and electron microscopy of protein - protein and protein - nucleic acid complexes, particularly those involved in DNA repair and transcriptional regulation.

He has been actively involved in the discovery of several nucleic acid and peptide drug leads that were progressed into clinical studies.

FINDINGS The researchers identified 32 known imprinted genes, but no new ones, implying that the list of imprinted genes in the mouse — at least in embryonic fibroblasts — is nearly complete, says Morison, who was not involved in the study (Nucleic Acids Res, 42:1772 - 83, 2014).

Large - scale and effective studies of biological molecules with a different structural basis such as proteins, nucleic acids, carbohydrates, lipids and numerous metabolites (including e.g. fatty acids, amino acids, purines, pyrimidines or steroids) is currently highly attractive because of the availability of modern instruments and tools for both separation and analysis (2 - D chromatographs, capillary electrophoresis systems, microfluidics, mass spectrometers, powerful NMR spectrometers, DNA / RNA arrays and others).

The Unit's scientific mission covers the design, synthesis, molecular modeling, as well as biophysical, biochemical and cellular studies of small - molecule probes and drug candidates targeting nucleic acids or proteins involved in cancer.

This study, published in Nucleic Acids Research, March 9 2018, disclosed part of the pathophysiological mechanisms in the Kleefstra syndrome.

The study was led by Olof Emanuelsson, KTH Royal Institute of Technology / SciLifeLab and Jens Sundström, SLU Swedish University of Agricultural Sciences, and published in Nucleic Acids Research.

The Laboratory of Protein Structure (LPS) started its activities in 2008 and focuses on structural and biochemical studies of proteins (e.g.: nucleic acid enzymes) using protein crystallography as the primary method.

That includes a study published in 2014 in Nucleic Acids Researchthat found resveratrol stops the formation of inflammatory factors involved with cancer, cardiovascular and chronic inflammatory diseases.