One emergency critical care resident
studied patients receiving Procalamine as part of their treatment protocol.
The study patients received either a minimally invasive TAVR procedure — which uses a catheter that is routed through a blood vessel in the leg or chest to access the heart — or an open - heart surgery to replace the valve.
All of
the study patients received biological valves, developed from animal or donated human tissue.
Not exact matches
«More than twice the number of
patients [were] still living at the end of the
study after
receiving IMAB362 plus chemotherapy compared to chemotherapy alone,» according to Ganymed CEO Özlem Türeci, with
patients showing the highest level of that protein biomarker responding best to the treatment.
These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial results; Gilead's ability to sustain growth in revenues for its antiviral and other programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount of discount required on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a larger than anticipated shift in payer mix to more highly discounted payer segments and geographic regions and decreases in treatment duration; availability of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror
patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction of generic versions of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect of lowering prices or reducing the number of insured
patients; the possibility of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to
receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and
patients may not see advantages of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical
studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).
The
study evaluated 344
patients and was randomized, with 321
receiving a
study intervention; 163, angiotensin II; and 158, a placebo.
A 2001 double - blind
study at the Mayo Clinic randomized 799 discharged coronary surgery
patients into a control group and an intercessory prayer group, which
received prayers at least once a week from 5 intercessors per
patient.
Intrepid readers of SHS will recall that I wrote about a
study — based on interviews with family members — showing that some
patients received lethal prescriptions before experiencing serious symptoms — out of worry about future potential pain or loss of dignity.
The double - blind
study (meaning neither the researchers nor the
patients know if they are
receiving the coconut oil or placebo) at the Byrd Alzheimer's Institute, located in Tampa, Florida, will be eight months long and will enroll about 65 people with mild to moderate Alzheimer's disease.
In response to reports that women may be using this unapproved drug, to increase milk production (lactation), the WHO and FDA are warning breastfeeding women of safety concerns as «there have been several published reports and case
studies of cardiac arrhythmias, cardiac arrest and sudden death in
patients receiving an intravenous form of domperidone that has been withdrawn from the market in a number of countries.»
However, the
study did not examine
patients that were exclusively breast - fed, and approximately 49 % of infants
received supplemental formula.
There is an irony that the report from the «Centre for policy
studies» failed to mention that the NHS is the only public body, that we are aware of, that has it's own full time litigation authority costing some # 7 million per year set up to deal with the complaints from
patients regarding treatment they have
received from a healthcare system that is supposed to protect them.
Fluge and Mella are now working on a multicenter
study and monitoring their original
patients as they
receive booster treatments, to try and determine optimal treatments for CFIDS.
While the researchers did not directly compare survival rates and neurological outcomes with whether individual
patients received bystander CPR or defibrillation, they did find increases in both over the duration of the
study.
Researchers looked at data on 74 300
patient who
received metformin and sulfonylurea, another common diabetes drug, over a 25 - year
study period.
Brennan D. Eadie, M.D., Ph.D., of the University of British Columbia, Vancouver, and colleagues conducted a
study that included
patients who had
received intravitreous bevacizumab injections for exudative age - related macular degeneration.
Of the
patients who
received the high dose in
study, 11
patients are able to speak, 11
patients are fed orally and seven do not require bi-level positive airway pressure as of the data cut - off (August 7, 2017).
The
study finds that OSI was associated with 331 fewer
patients a month
receiving prescriptions with daily doses above 100 MEQ, and 164 fewer
patients a month being prescribed a daily dose above 200 MEQ.
One example: A high number of
patients in the new
study had
received CPR and therefore a restored heartbeat sooner.
In the
study, 64
patients received the topical ocular insert containing the glaucoma drug bimatoprost.
ORLANDO, Fla. — The first large
study to examine cumulative radiation exposure from medical imaging after a heart attack has found that the average
patient receives the equivalent of about 725 chest X-rays before leaving the hospital.
This
study analyzed preserved tumor samples from 43 prostate cancer
patients who later
received radiation therapy after rising PSA levels were detected following a radical prostatectomy.
Patients with age - related macular degeneration who
received seven or more eye injections of the drug bevacizumab annually had a higher risk of having glaucoma surgery, according to a
study published online by JAMA Ophthalmology.
The
study found that OSI resulted in 781 fewer
patients each month
receiving both an opioid and a benzodiazepine.
Despite the advent of a new generation of stents,
patients with multiple narrowed arteries in the heart who
received coronary artery bypass grafting fared better than those whose arteries were opened with balloon angioplasty and stents in a
study presented at the American College of Cardiology's 64th Annual Scientific Session.
These antianxiety drugs «are known to be safe, and we are using them at very low levels here,»
study author Scheuer notes, adding he is not concerned about human
patients receiving low doses of antianxiety drugs off - label.
Results presented today at The International Liver Congress ™ 2015 demonstrate that hepatitis C (HCV)- infected genotype - 3 (GT - 3)
patients, with and without cirrhosis,
receiving 24 weeks of sofosbuvir (SOF) in combination with ribavirin (RBV) and peginterferon (PEG) achieved the highest sustained virologic response rates at 12 weeks (SVR12), observed in a Phase 3
study, to date.
The idea to specifically
study this group of
patients was based on groundbreaking research Garon published in the New England Journal of Medicine last year, which found that among
patients who
received pembrolizumab, those with PD - L1 expression on at least 50 percent of their cancer cells showed the longest survival and disease control.
In the new
study,
patients receiving angioplasty with the new stents had a 47 percent higher risk of one of the outcomes identified as a primary endpoint in the
study: death, heart attack and subsequent procedure to clear blocked arteries, as compared to
patients who
received bypass.
In a 2010
study, Maria Semkovska and Declan M. McLoughlin of Trinity College in Dublin reviewed 84
studies of 2,981
patients who
received ECT.
The
study included 39,140 opioid - naive
patients, of whom 53 percent
received 1 or more opioid prescriptions within 90 days after discharge.
The NAPOLI - 1 (NAnoliPOsomaL Irinotecan) Phase 3
study — a final confirmation of a drug's safety and effectiveness — was conducted among
patients with metastatic pancreatic cancer who previously
received gemcitibine, which has been the standard - of - care therapy for such
patients.
One of the
studies, published in 2008, suggested that
patients whose antiretroviral treatment was deferred until their CD4 cell counts were below 250 were at greater risk of opportunistic infection than those that
received antiretroviral treatment when CD4 cell counts were higher than 350.
In this
study in a Berlin hospital, one
patient in five
receiving routine care suffered from postoperative delirium, whereas in the group
receiving support from delirium liaison nurses, fewer than 1 in 20 developed cognitive disorders.
For one thing, they point out, acupuncture
studies are extremely difficult to double - blind — a methodological approach in which neither the researchers nor
patients know who is
receiving the treatment under investigation and who is
receiving the placebo or sham.
Cardiac resynchronization therapy (CRT) devices, such as pacemakers, that are designed to electrically stimulate the heart to function normally fail to help as many as a third of
patients who
receive them each year, according to some
studies.
Throughout the
study period, a significant increase occurred in the proportion of
patients receiving bystander - initiated CPR, from 39.3 percent in 2010 to 49.4 percent in 2013.
Dr. Glen Weiss, M.D., M.B.A., is the first author of the
study abstract: Phase Ib / II Study of Pembrolizumab plus Chemotherapy in Advanced Cancer: Results of lung cancer patients receiving (at least) 1 prior line of the
study abstract: Phase Ib / II
Study of Pembrolizumab plus Chemotherapy in Advanced Cancer: Results of lung cancer patients receiving (at least) 1 prior line of the
Study of Pembrolizumab plus Chemotherapy in Advanced Cancer: Results of lung cancer
patients receiving (at least) 1 prior line of therapy.
The cinnamon
study, published in DiabetesCare, is the first to look at cinnamon in Americans with type 2 diabetes.The
patients received 1,000 milligrams of cinnamon a day for three months.
In addition, on average,
patients receiving nivolumab reported that their quality of life remained stable or improved throughout the
study, while those in the chemotherapy group reported a decline.
During the time covered in the
study, Hansen said, 86.3 percent of
patients received CPR before EMS arrived, with 45.7 percent initiated by bystanders and 40.6 percent by first - responders.
Many
patients with ulcerative colitis don't
receive recommended testing and treatment for the common problem of iron deficiency anemia, reports a
study in the October issue of Inflammatory Bowel Diseases, official journal of the Crohn's & Colitis Foundation of America (CCFA).
Depressed men with localized prostate cancer were more likely to be diagnosed with more aggressive prostate cancer,
received less effective treatments and survived for shorter times than prostate cancer
patients who were not depressed, a UCLA
study has found.
In this
study, the participating healthcare systems had a combined 7.5 million
patients age 18 or older, with about 1.2 million
patients receiving a psychiatric diagnosis in 2011.
The research findings can have a significant impact on our
patients» quality of life, and improve the precision of the treatment they
receive,» said co-author of the
study, Assoc Prof Tang Choong Leong, Head, Department of Colorectal Surgery at SGH.
For anxiety, there is one
study of 24
patients with social anxiety in which half
received a single dose of cannabis derivative and scored their anxiety doing a simulated presentation.
Patients with chronic wounds who never
receive opioids heal faster than those who do
receive the drugs, according to a new
study by George Washington University (GW) researcher Victoria Shanmugam, M.D.
To ensure that
patients can
receive all recommended care, we need to recognize the financial burden of cancer and identify
patients at risk for financial concerns,» says lead
study author Christine M. Veenstra, M.D., M.S.H.P., clinical lecturer in hematology / oncology at the University of Michigan Medical School.
Although both
studies have limitations, an editorial accompanying Graham's paper considered the findings compelling: «Accumulating concerns about rosiglitazone make it difficultto advance a cogent argument regarding why, exactly, a
patient might want to
receive the drug.»
«Although we observed that short - term use of LDX was well tolerated and effective in several subjective and objective areas, long - term
studies of menopausal women
receiving LDX are needed, similar to those conducted for ADHD
patients,» said Epperson.