Rick Perry and Michele Bachmann, two presidential candidates who sparred over the issue of Texas vaccinations, may be floundering in the polls, but the topic of Merck's controversial Gardasil is heating up — with an Austrian physician who
studied the drug saying it is not only dangerous, but useless in reducing cervical cancer, the stated reason it was administered to young girls at the behest of Gov. Perry.
Not exact matches
Says Bapty: «If a CRO is nimble and can evolve technology that can enable its clients to get a
drug approved faster or to reduce the risk of a clinical
study, or even save them development money in the long run, that company will find it has a long - term business plan.»
On May 30, Gilead
said it found in four late - stage
studies that its its
drug, bictegravir, wasn't inferior to ViiV's dolutegravir.
«By having 1 million individual users you can get to a scale where researchers are running data queries through 23andMe, where
drug studies leverage our data, and where individuals can more easily be connected to
studies that could benefit them,» Wojcicki
said.
«The DEA appears to be dragged into this kicking and screaming,»
said Sanho Tree, director of the
Drug Policy Project at the Institute for Policy
Studies, a progressive think tank focused on social - justice issues.
Shares of Ligand Pharmaceuticals shed nearly 12 percent Tuesday after Amgen
said its multiple myeloma
drug, Kyprolis, did not outperform Takeda Pharmaceutical's Velcade in a late - stage
study.
Shares of Ligand Pharmaceuticals plunged 12 percent Tuesday after Amgen
said its multiple myeloma
drug, Kyprolis, did not outperform Takeda Pharmaceutical's Velcade in a late - stage
study.
The institute, which includes over 40 laboratories and more than 300 researchers,
said the research would focus on modifying a patient's own immune system T - cells to target a tumor,
studying ways to boost patient response to current immunotherapy
drugs.
Pagan
said that a larger, more comprehensive
study must be done before determining the
drug's true impact, but if the
drug's effectiveness is confirmed in such tests, nilotinib could become the first treatment to impede the killing of brain cells that's consistent with Parkinson's, according to NPR.
In an editorial accompanying the new
study, Dr. Wilson Compton of the National Institute on
Drug Abuse in Bethesda, Maryland, and colleagues
say policymakers need to understand which parts of medical marijuana laws are tied with positive and negative effects.
«The intensifying battle for negotiating power and market share will lead companies to do acquisitions across traditional industry boundary lines,»
said Erik Gordon, a professor at the Ross School of Business at the University of Michigan who
studies the
drug industry.
A recent U.S. Government Accountability Office
study said the FDA inspects foreign
drug manufacturing facilities about once every 11 years.
Alnylam, which has been weighed down in the past by
drug safety concerns,
said it plans to initiate a program targeting cardiomyopathy - another symptom of the disease - alongside polyneuropathy in a late - stage
study next year.
Credit Suisse analysts
said patisiran's data seemed to have «solid safety» compared with Ionis Pharmaceuticals Inc's rival
drug, which cleared a key
study but raised safety concerns.
The
drug is presently in a third late - stage
study, and Alkermes
said it plans on updating investors on the progress of this remaining
study later this year.
The
study, published in the January edition of the British Journal of Psychiatry,
says spiritual but not religious people, as opposed to people who are religious, agnostic or atheist, were more likely to develop a «mental disorder,» «be dependent on
drugs» and «have abnormal eating attitudes,» like bulimia and anorexia.
CNN: The spiritual but not religious likely to face mental health issues,
drug use,
study says Can being spiritual but not religious lead to mental health issues?
«They almost always use
drug metaphors, like «higher than any high you can experience,»
said Paul Williamson, a professor of psychology at Henderson State University in Arkansas who
studies serpent handlers.
Joseph Califano Jr., president of the National Center on Addiction and Substance Abuse at Columbia University,
said his group's
study concluded that many dads are essentially AWOL when it comes to keeping their children
drug free.
According to the Canadian Medical Association in response to a recent
study that
said Canadian women are not heeding pregnancy warnings about the use of isotretinoin, a potent but effective
drug that treats severe acne.
«The current messages
saying that bed sharing is dangerous only if you or your partner are smokers, have been drinking alcohol or taking
drugs that make you drowsy, are very tired or the baby is premature or of low - birth weight, are not effective,» the authors wrote in the
study, adding that doctors need to «take a more definitive stance against bed sharing for babies under three months».
«The general recommendation is to totally avoid
drug abuse while breastfeeding, because these substances can pass directly through to the newborn,» Óscar García Algar, co-author of the
study and a doctor in the Paediatrics Department at the Hospital del Mar in Barcelona,
said.
Let's
say the blogosphere is abuzz about a research
study that shows that sleep - training methods like cry - it - out have no long - term effects on children or that physically punitive discipline tactics like spanking result in children who are better behaved or that birthing without
drug pain relief is dangerous.
But critics argue that the
study has not been peer reviewed or published in a scientific journal, and the U.S. Food and
Drug Administration has
said that food coming in contact with the chemical is safe, even in baby feeding bottles.
Mrs. Alarbi
said studies showed that for babies born to HIV - infected mothers, the use of niverapine
drug combined with baby formulas to prevent mother - to - child transmission, could reduce child mortality to only two per cent of under - five mortality and morbidity while the use of insecticide - treated bed nets could reduce it by six per cent.
Many women don't want to deliver in a hospital because they fear their choices — to avoid
drugs, to avoid surgery, to be surrounded by their families, to be with the baby immediately after delivery — will be taken away,
said Carolyn L. Gegor, program director of the Nurse Midwifery / Women's Health Nurse Practitioner Program in the School of Nursing and Health
Studies at Georgetown University Medical Center.
Since then an advisory committee to the US Food and
Drug Administration has been
studying whether the process is safe, after a Portland researcher
said he had conducted the technique successfully on monkeys - and now wanted to begin trying it on humans.
Bultman
says The research has been difficult to weigh for health - care practitioners and doctors in part because some
studies have focused on smoking the
drug — which isn't allowed in New York or Minnesota.
Home secretary tried to alter 2014
study that found no link between tough laws and illegal
drug use,
says ex-deputy PM
The spokesperson also rejected the idea that the report, known as the International Comparators
Study,
said there was no link between tough penalties and
drug use.
Since the neuronal death can be recapitulated in directly reprogrammed patient neurons, Yoo
said the new technique offers a way to
study the details of how potential therapies — including
drugs that are currently being tested in clinical trials — could rescue medium spiny neurons from death.
He also
said that the
study showed it was possible to run a randomized, controlled trial in the middle of an international health emergency, which is important to make sure any new
drugs do not cause more problems than they address.
Since gabapentin's release in 1993, there have been no human laboratory
studies done on the
drug, Vickers Smith
said.
«I'd be surprised if playing online games for 10 to 12 hours a day didn't change the brain,»
says neuroscientist Nora Volkow of the National Institute on
Drug Abuse, who wasn't involved in the
study.
The sacks could be used as a new way to deliver
drugs,
say the researchers, whose
study appears in the current issue of Science.
«Our findings are consistent with previous
studies showing an association between the legalization of medical marijuana and lower deaths from overdoses of opioids,»
said Rosalie Liccardo Pacula, co-author of the
study and co-director of the RAND
Drug Policy Research Center.
Strict
drug laws have delayed those types of
studies for decades, Slot
said.
«The median percentage reduction in seizure frequency was more than 29 percent for patients on a low - dose regimen of everolimus and nearly 40 percent for patients with high - dose regimen to the
drug,»
says David Franz, MD, founding director of the TSC Clinic at Cincinnati Children's Hospital Medical Center and the
study's senior author.
However, the US Food and
Drug Administration
says that, currently, «all approved high - intensity sweeteners have been thoroughly
studied and have a reasonable certainty of no harm to consumers under their approved conditions of use».
New research finds flaws in a 2009
study that had provided hope and one scientist
says CFS patients should stop taking antiretroviral
drugs based on those findings
«The potential link between a
drug and suicide is a particularly difficult topic to
study,» Antoon
said.
People with
drug addictions who started opioid abuse later in life use injections for their
drugs, or increased their use of downers before starting
drug treatment, are more likely to relapse from treatment than others,
says a new
study from McMaster University.
Professor Adeeba Kamarulzaman, an author on the
study from University of Malaya, Malaysia,
said: «In recent years, compulsory
drug detention centres in Malaysia and across Asia have come under scrutiny and question over their lack of effectiveness in treating addiction and their human rights transgressions.
«We approached this problem many years ago and have seen all kinds of
studies, and there isn't anything definitive to
say that antibiotics in livestock cause harm to people,»
says Richard Carnevale, vice president of regulatory and scientific affairs at the Animal Health Institute, which represents the manufacturers of animal
drugs, including those for livestock.
«It is exciting to have an expanded group of patients who are now eligible for this
drug,»
said Garon, whose clinical
studies helped lead to today's FDA approval.
«If you were to develop a
drug to treat PTSD, you'd want it to do exactly what MDMA does,»
says Rick Doblin, founder and executive director of the Multidisciplinary Association for Psychedelic
Studies (MAPS), which funds and conducts the research.
Richard Hargreaves, executive director of imaging at Merck Research Laboratories,
says, «Nuclear imaging using radiotracers gives the opportunity to put your arms around proof - of - concept very early in a
drug discovery and development program by focusing the selection of doses to
study on those proven to deliver enough
drug to the target therapeutic sites.»
Writing in a linked Comment, Gino Vumbaca from Harm Reduction Australia,
said: «Evidence on the effectiveness of compulsory and voluntary
drug dependence treatment in the Asian region has been scarce and this
study is a much needed addition to the evidence base that is required to inform policy making... The present
study provides solid evidence in support of urgent need to expand availability of and access to evidence based voluntary
drug dependence treatment approaches to all whom are affected by
drug dependence.
«What's frightening about this emerging street
drug is that users themselves may not be aware that they are ingesting it,»
said lead
study author John Stogner, Ph.D. of the Department of Criminal Justice and Criminology at the University of North Carolina at Charlotte, N.C. «A patient may report heroin use and have symptoms consistent with heroin overdose, but an emergency physician may find that the standard dose of antidote (naloxone) doesn't work.
The
study is an important demonstration that a
drug might be used to repair brain damage, Gallo
says.