Sentences with phrase «studied zebrafish»

In a study by Junker et al, the authors studied zebrafish embryos at the 15 somites stage by straightening them, then segmenting them into about 100 slices, each roughly 18 µm thick.

To elucidate the roles of eya4 in heart function, we studied zebrafish embryos injected with antisense morpholino oligonucleotides.

«We studied a zebrafish gene that is analogous to a human gene that causes deafness, and here we show the defect is in the process of mechanotransduction.»

Having spent his first 5 years in that position establishing his own research theme and tools to study zebrafish development, «now it is thanks to this programme that I can expand and fully develop it.»

National Institutes of Health researchers studying zebrafish have determined that a population of cells that protect the brain against diseases and harmful substances are not immune cells, as had previously been thought, but instead likely arise from the lining of the circulatory system.

The Weinstein lab studies zebrafish to understand how the blood and lymphatic systems develop.

Monk and her team study zebrafish because they are excellent models of the vertebrate nervous system.

Studying zebrafish is a vitally important way to discover what role genes play in human health and disease.

In the context of ethorobotics, we have recently proposed a series of dichotomous preference tests to study zebrafish response to an anchored robotic fish whose design is inspired by salient features of attraction in zebrafish.

Not exact matches

Since then, they have studied this protein in flies, mice, zebrafish and humans.

McGlinn will work within the supportive environment of ARMI, where 54 researchers are prying into the mysteries of vertebrate regeneration by studying sharks, mice, chickens, axolotls, and zebrafish.

For the study, the researchers created a line of zebrafish with defective immune systems by inserting a mutation into a gene required for development of an important component of the immune system.

«Microbial dispersal impacts animal guts: Study with zebrafish finds that transmitted microbes will lead to similar microbiomes and a selection process for some microbes.»

In a study appearing in the journal Integrative Biology, the researchers used this technology to identify materials that can efficiently deliver RNA to zebrafish and also to rodents.

Studies found that a derivative excreted by juiced cattle reduces minnows» fertility, transforms female zebrafish into males, and induces other masculinizing effects.

Soon after, an alarm sounded at the fish facility down the hall, and Jesus Torres - Vasquez, who studies blood - vessel formation in zebrafish, came up to check.

The study found that zebrafish that failed to inherit specific genetic instructions from mom developed fatal defects earlier in development, even if the fish could make their own version of the gene.

Engert, an associate professor in Harvard's Department of Molecular and Cellular Biology, studies vision and cognition by monitoring brain activity in zebrafish.

A group of researchers recently tried to settle this debate by studying the larvae of a common see - through aquarium pet, the zebrafish.

In the study, Burdine and two graduate students Jose Pelliccia and Granton Jindal used CRISPR / Cas9 gene editing to remove Vg1, known as Gdf3 in zebrafish.

Although reindeer noses aren't typically red, or infused with enough light to guide a sleigh, Farber says other earthly creatures are that color and glow through bioluminescence or fluorescence — everything from jelly fish to sea anemones to the zebrafish he studies.

Zebrafish larvae a few days old are frequently used in toxicology tests — e.g. to study the behavioural effects of drugs — in order to avoid experiments in mammals.

Different types of studies use different stand - ins: Flies for genetics; zebrafish for early development; rats and mice and monkeys for cancer, neuroscience and more.

«Zebrafish could have a unique niche [in cancer treatment],» says Leonard Zon of Harvard Medical School in Boston, who has used the fish for more than a decade to study how cancer develops.

A study by Eawag and Zurich University researchers using a new imaging method has revealed that, surprisingly, cocaine accumulates in the eyes of zebrafish.

Still, Zon cautions that not all human drugs work in zebrafish, so «we need to study a lot more patients to see, in a broad view, how this approach performs.»

Often, those smaller animals express the genetic abnormality very differently from humans, says clinical scientist and pediatric neurologist James Dowling at the University of Michigan, Ann Arbor, who studies the myopathies and their genetic causes in both children and zebrafish.

Together, studies in zebrafish and mammalian models could inform new ways to manipulate glial cells after human spinal cord injury.»

Using a novel combination of technologies, including trio exome sequencing of patient / parental DNA and genetic studies in the tiny larvae of zebrafish, the EuroEPINOMICS RES consortium found that mutations in the gene CHD2 are responsible for a subset of epilepsy patients with symptoms similar to Dravet syndrome — a severe form of childhood epilepsy that is in many patients resistant to currently available anti-epileptic drugs.

«Zebrafish study sheds new light on human heart defects.»

Yin is using zebrafish to study the regeneration of heart tissue because of the amazing capacity of these common aquarium fish to regenerate the form and function of almost any body part, including heart, bone, skin and blood vessels, regardless of their age.

«Now, through our new study, we show that lowering levels of a particular cohesin protein called Rad21 in embryonic zebrafish produces similar types of heart defects to those found in people with CdLS,» Associate Professor Horsfield says.

«Zebrafish brain repair following concussion: New model enables study of animal's remarkable ability to regenerate injured brain tissue.»

The zebrafish larva is an ideal model to study genes involved in epilepsy, and the methods necessary for such studies are now well - established in our laboratory.

In a study performed by North Carolina State University researchers, zebrafish that were bred to be more bold — quantified by the shorter amount of time they remained motionless when placed in new surroundings — displayed a sleeker body shape and an ability to dart around the water more quickly when startled than those bred to be more shy.

In the study, the researchers used zebrafish lines that had been selected to be bolder by breeding fish that stayed still for a maximum of 50 seconds after being introduced into new surroundings, while shy fish — those that stayed still for more than 3 minutes when dropped into a new area — were bred to create a shy line.

Study co-author John Rawls of Duke and his group are studying the biological mechanisms underlying the absorption of lipids — fatty acids and related fat molecules — in the guts of zebrafish.

Based on analyses of scales from highly relevant species for aquaculture such as common carp (Cyprinus carpio), gilthead sea bream (Sparus aurata), sea bass (Dicentrarchus labrax), Mozambique tilapia (Oreochromis mossambicus), Atlantic salmon (Salmo salar), rainbow trout (Oncorhynchus mykiss) and pike perch (Stizostedion lucioperca) as well as from fish commonly used in experimental studies such as zebrafish (Danio rerio), it was found that glucocorticoids, especially cortisol, incorporate in fish scales over time.

The study imaged live zebrafish over time to track the development of melanoma.

Zebrafish can find a way to compensate for a mutated gene, but artificial methods of inactivating the same gene are not so readily overcome, a new study suggests.

Scientists established the importance of Stac3 for muscle function in zebrafish by studying the small fish physiologically and genetically.

In the current study, the researchers showed that FGPs are present on the surface of the zebrafish brain and that these blood vessel - associated FGPs do not arise from the immune system, as had been previously thought, but from endothelial cells themselves.

Dr. Lyons and his team used zebrafish to study the formation of myelin sheaths by oligodendrocytes because this laboratory animal is transparent at early stages of its development, which allows investigators to directly observe cells within the organism.

Tobin also uses zebrafish to study bacteria closely related to those that cause tuberculosis, and findings from this model have been applied to understanding human disease.

A new study at the University of Oregon, led by postdoctoral fellow Annah Rolig, took aim at that question with experiments in zebrafish to dissect whether changes in the abundance of certain gut bacteria can cause intestinal inflammation.

In the new study, conducted in zebrafish, researchers found that elimination of the α - synuclein protein protected the zebrafish against the ziram - induced loss of dopamine neurons.

These studies demonstrate that inflammatory intestinal pathologies, such as Hirschsprung - associated enterocolitis or inflammatory bowel disease, can be explained as an overgrowth of certain pro-inflammatory groups of bacteria or a loss of anti-inflammatory bacteria, said Judith Eisen, a professor of biology and an expert on gut neurons in zebrafish.

Zebrafish embryos are used for the assessment of chemicals and for investigations of environmental impact, so we hope that in future our study will contribute to an awareness of the need to incorporate Abcb4 transport processes in toxicological testing directives.»

The study, published Feb. 16 in PLOS Biology, made use of a mutant zebrafish strain that models human Hirschsprung disease, which is caused by loss of the gut neurons that coordinate gut contractions.

His group studies the cellular and genetic control of gastrulation movements in zebrafish, one of the model organisms studied at the institute besides Drosophila, the C. elegans worm, frogs, mice, and newts.