Ed's research team
studies cerebrospinal fluid in Huntington's disease and he is the global Chief Investigator of the HDClarity study.
Chun's group has started
studying cerebrospinal fluid and other human samples, to see what LPA is doing there.
Not exact matches
«This
study provided clear evidence that, in people with early Parkinson disease, inosine treatment can safely elevate urate levels in the blood and
cerebrospinal fluid for months or years,» says Michael Schwarzschild, MD, PhD, principal investigator of the
study and an MGH neurologist.
Studies using brain MRI and analysis of the
cerebrospinal fluid may help to demonstrate signs of inflammation,» said Josep Dalmau, MD, PhD, adjunct professor of Neurology.
Professor Aneta Stefanovska from Lancaster University, who has been
studying the physics of biological oscillations for over 20 years, said: «Combining the technique to noninvasively record the fluctuation corresponding to
cerebrospinal fluid and our sophisticated methods to analyse oscillations which are not clock - like but rather vary in time around their natural values, we have come to an interesting and non-invasive method that can be used to
study aging and changes due to various neurodegenerative brain aging may begin earlier than expected.»
Migraine sufferers have significantly higher sodium concentrations in their
cerebrospinal fluid than people without the condition, according to the first
study to use a technique called sodium MRI to look at migraine patients.
Apart from the number of participants, the strengths of this
study include the use of three different methods to achieve acurate measurement results:
cerebrospinal fluid samples, the use of a so - called PET scanner, and genetic analysis.
«Oxytocin levels in blood,
cerebrospinal fluid are linked,
study finds.»
Further
studies, including analysis of frozen blood and
cerebrospinal fluid taken from patients, are underway to test possible drug mechanisms.
Zika virus can persist in
cerebrospinal fluid (CSF), lymph nodes and colorectal tissue of infected rhesus monkeys for weeks after the virus has been cleared from blood, urine and mucosal secretions, according to a
study published online in Cell.
Conducting a cross-sectional
study of a large cohort of patients with different levels of cognitive impairment and different disease stages, the researchers found that the amounts of a TREM2 fragment in the
cerebrospinal fluid were highest during early stages characterized by mild cognitive impairment symptoms.
Brain imaging
studies and
cerebrospinal fluid analysis for both patients were consistent with Alzheimer's disease.
«To date,
cerebrospinal fluid analyses have not been a routine component of assessment and care for patients with cognitive impairments and suspected Alzheimer's disease in the United States,» Dr. A. Zara Herskovits, of Brigham and Women's Hospital, and Dr. John H. Growdon, of Massachusetts General Hospital, wrote in an editorial that accompanied the
study.
The
study conducted in the laboratory of Don Cleveland, Ph.D., UCSD Professor of Medicine, Neurosciences and Cellular and Molecular Medicine and member of the Ludwig Institute for Cancer Research, shows that therapeutic molecules known as antisense oligonucleotides can be delivered to the brain and spinal cord through the
cerebrospinal fluid (CSF) at doses shown to slow the progression of ALS in rats.
Su
studied plasma and
cerebrospinal fluid samples previously collected from patients undergoing diagnostic evaluation, who were later identified as having ALS.
Structural eye anomalies (in particular, microphthalmia and coloboma), cataracts, intraocular calcifications, and posterior ocular findings have been reported in infants with presumed and laboratory - confirmed prenatal ZIKV infection; however, posterior findings have been the most prevalent.21,25,28,33,35,36,41 - 43 Case series report chorioretinal atrophy, focal pigmentary mottling of the retina, and optic nerve atrophy / anomalies.28, 34,37,41 - 43,55 Series of 20 or more infants with presumed ZIKV - associated microcephaly report ocular findings in 24 % to 55 %.28, 33,42 In one
study, testing for ZIKV IgM was performed in 24 of 40 infants (60 %) with microcephaly and the results were positive in the
cerebrospinal fluid in 100 % of those tested.42 The proportion of infants with ocular lesions did not differ in those with and without testing.42 In that series, first trimester maternal infection and smaller head circumference significantly correlated with the presence of abnormal ocular findings.42
Background:
Studies conducted in animal models and humans suggest the presence of a dynamic equilibrium of amyloid - β (Aβ) peptide between
cerebrospinal fluid (CSF) and plasma compartments.
Abstract: Background:
Studies conducted in animal models and humans suggest the presence of a dynamic equilibrium of amyloid - β (Aβ) peptide between
cerebrospinal fluid (CSF) and plasma compartments.
A review of
studies showed that people with Alzheimer's had lower magnesium levels in their
cerebrospinal fluid than those who did not have the disease.
Studies have demonstrated that ear stimulation increases levels of endorphins in both the blood and
cerebrospinal fluid.
Consistent with preclinical
studies, adults with depression have been reported to have multiple alterations of the hypothalamic pituitary adrenal axis (9), increased
cerebrospinal fluid corticotropin - releasing hormone (10), elevated
cerebrospinal fluid norepinephrine concentration (11), decreased cortical γ - aminobutyric acid measured in vivo using proton magnetic resonance spectroscopy (12), and multiple indicators of altered serotonin (5 - HT) functioning (13), including reduced serotonin transporter (5 - HTT) availability as evidenced by reduced [123I] β - CIT spect binding (14).