The Hu laboratory
studies endoplasmic reticulum (ER), which has critical functions in lipid synthesis, calcium storage and drug metabolism.
Not exact matches
His laboratory currently applies high throughput imaging technologies to
study trafficking between the
endoplasmic reticulum and Golgi complex, and the internalization pathways taken by synthetic nanoparticles on exposure to cells.
Based on the
study of the RB51 - macrophage interaction model,
endoplasmic reticulum stress activates the inflammasome via NLRP3 - and caspase -2-driven mitochondrial damage (Bronner et al, 2015).
He joined the Polleux lab in 2017 where he
studies how the
endoplasmic reticulum (ER) and mitochondria networks regulate spatiotemporal dynamics of dendritic calcium in the context of synaptic integration, plasticity, circuit function and behavior.
A new
study conducted by researchers at The Wistar Institute revealed how a key protein residing in the
endoplasmic reticulum (ER) helps cells respond to stress.
Current
studies have demonstrated that the chronic
endoplasmic reticulum stress and oxidative stress play an important role in development and progression of AP [4, 5].
Cell biologist Tom Rapoport may be best known for
studies of how proteins get in and out of a convoluted compartment inside cells called the
endoplasmic reticulum (ER).
Thus, our
study shows that membrane exchange between the early endocytic and the biosynthetic / secretory pathways involves specific components of the Rab and SNARE machinery, and suggests that retrograde transport between early / recycling endosomes and the
endoplasmic reticulum is critically dependent on the sequential action of two members of the Rab6 subfamily.