Dr. Ahmed
studies immunological memory — the ability of the immune system to «remember» a particular antigen and respond accordingly.
Gilead and Verily will work together for three years to
study the immunological nature of rheumatoid arthritis, irritable bowel syndrome and diseases related to lupus, the companies said after trading closed Monday.
The mouse model should also be useful for
studying the immunological reactions and viral clearance in hepatitis B virus infection, they note in the Journal of Virology.
She is currently a Research Fellow who is
studying the immunological and virological characterization of HIV -1-infected patients who are taking antiretroviral therapy and various viral reactivation agents in several ongoing clinical trials.
I also
study the immunological and neurological mechanisms involved in nutrition, herbal medicine, acupuncture, and mind - body therapies, with specific interest in the gut - brain axis in Parkinson's disease.
Not exact matches
Previous
studies of the staying power of mother's milk had found that many of its benefits are not affected by refrigeration, and that bacteriological, nutritional and
immunological advantages for infants continue after the milk is expressed and stored.
Though no conclusive
studies have been done to identify the
immunological components of breast milk for children past 2 years of age, there's no reason to suppose they stop cold turkey once baby reaches a certain age.
There is good microbiological and
immunological evidence for the different mechanisms by which breast feeding confers protection against diarrhoea, 5 but few epidemiological
studies have measured their relative importance.
According to a new
study, these babies face a greater risk of developing
immunological disorders compared to children born naturally.
Through continued
study, breastmilk has been shown repeatedly to have a wide array of effectiveness against disease - causing agents and lead to an overall positive
immunological effect on the health and well being of the infant and mother.
What is known through
studies is that babies that are continued to be breastfed continue to receive
immunological benefits from the immunoglobulins, lysozyme, lactoferrin, complement, lactoperoxidase, macrophages, lymphocytes, interferon, «antistaphylococcal factor,» and «bifidus factor» contained in breastmilk.
Researchers
studied HIV positive individuals, ages 30 to 50 years, who did not have osteoporosis, had no history of
immunological disease other than HIV, had serum vitamin D and calcium levels within the normal range, and normal CBC and blood chemistry profiles.
«There are many
studies in humans, and at least one in chimpanzees, showing that from an
immunological perspective, juveniles and children are really important for maintaining diseases in populations through play and things like that,» she said.
The authors are continuing their
study of urban impacts on finches — emphasizing the behavioral and
immunological impacts of humans and urban parasites on the birds.
«Even with the new
immunological studies, we can't tell what's special about the whole - cell vaccine that makes it better,» says Kathryn Edwards, the director of the Vanderbilt University School of Medicine Vaccine Research Center.
Because the researchers found that CTLA4Ig was effective in suppressing hepatitis in this
study, they suggest that CTLA4Ig should be among the therapeutic options investigated further as a potential therapy for patients with severe acute hepatitis B. To this end, this animal model is useful for virological and
immunological analysis of HBV infection.
Arguing that «this high degree of complexity both in terms of
immunological outcomes and underlying mechanisms, necessitates that HDAC inhibitors be
studied in a context that is matched to their intended utility,» Brad Jones, from the Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology and Harvard, Boston, USA, and colleagues set out to test whether the three drugs affected the ability of CTL to eliminate HIV - infected target cells.
Among areas the panel says should be
studied further are possible cancer, reproductive, neurological, and
immunological effects of endocrine disruptors.
In the new
study, scientists built upon previous discoveries that a safe, non-reproducing vaccine strain of T. gondii could cure mice of several types of solid tumors, and identified which parasite proteins and which
immunological pathways are required to break immune tolerance.
We therefore asked ourselves whether an
immunological memory in these long - lived microglia could be communicating this risk,» explains Dr. Jonas Neher, head of the current
study and a scientist at the DZNE and the HIH.
«Because of the direct link between nicotine itself and inflammation, this
study has important implications including that alternative forms of nicotine inhalation, such as vaping that lacks other chemicals from cigarette smoke, may nonetheless still have detrimental
immunological effects.»
«The
study clearly shows that it is possible to achieve an
immunological antibody memory with mucosal vaccination and that the memory cells that are created in connection with this type of vaccination are unique and can not be achieved through traditional vaccination methods.
The European research collaboration behind this
study focuses on deep
immunological analysis of the immunogenicity and reactogenicity of the Ebola vaccine in healthy volunteers.
The
study gathered information on environmental, genetic, and
immunological factors collected from blood samples and questionnaires between 1996 and 2014.
«The
study results suggest that
immunological changes during pregnancy may affect the response to the vaccination,» stated Emily Patel, M.D. with Duke University.
«There is an
immunological case of mistaken identity,» explains
study author Lawrence Steinman of Stanford's Beckman Center for Molecular Medicine.
The
study is the first to provide
immunological evidence on the role of gestational infection in autism, reporting an association between maternal anti-herpes simplex virus - 2 (HSV - 2) antibodies and risk for ASD in offspring.
The
immunological benefits from the wild mice's gut bacteria may, in part, explain a persistent problem in disease research: Why disease experiments in lab mice, such as vaccine
studies, turn out very differently in humans or other animals.
Arturo Casadevall, chair of the Department of Microbiology and Immunology and director of the Center for
Immunological Sciences at the Albert Einstein College of Medicine, who has been
studying Cryptococcus for over 20 years, has compared the phenomenon with a card game where soil microbes are playing for survival, but by chance, a few hands confer «accidental virulence» on other hosts.
Molecular, subcellular and cellular
studies in whole animals or humans; and novel molecular,
immunological or biophysical
studies of hormone action are also featured.
Furthermore, this
study also encourages the application of iPSC - MSCs as an exciting new therapeutic option for a range of
immunological disorders and suggests that further
study of the secreted factors may allow the construction of efficient cell - free therapies in the near future.
These
studies led to the discovery of the
Immunological - Synapse.
«Cytokines provide the intercellular communication links between the immune system and other tissues and organs... Thus, the
study of cytokines has helped to propel immunology from the limited areas of
immunological specificity to larger concerns of the cell biology, biochemical, molecular, and clinical aspects of host defense.»
The robust immunomodulatory capabilities of mesenchymal stem cells (MSCs) have propelled them into animal
studies and preliminary clinical trials as a treatment for a series of
immunological diseases.
This
study looks at variation in one
immunological message, and finds that people with the uncommon version of the gene will make more antibodies after being vaccinated.
Our microscopy
studies with quantitative co-localization analysis revealed the presence of intraneuronal Aβ in transgenic rats, with an
immunological signal that was clearly distinguished from that of the amyloid precursor protein (APP) and its C - terminal fragments (CTFs).
«The level of Lactobacilllus phage phiadh correlated with the prevalence of
immunological disorders... which has been shown in animal models to alter the microbiome,» the Johns Hopkins
study said.
[5] The primary outcome of the
study was safety and tolerability, with
immunological response to the vaccine as a secondary outcome.
The successful candidate will
study how defined immune evasion functions encoded by CMV impact on
immunological control of virus, and the progression of disease.
Currently, at the Ragon Institute of MGH, MIT & Harvard, she will be focus on the
study of different pharmaceutical and
immunological strategies to reduce HIV - 1 persistence.
Career Goal: My future career goal is to obtain a PhD in Immunology, a field of
study in science which fascinates me, and, ultimately, to pursue a career in scientific research of
immunological diseases.
Our group focuses on developing pharmaceutical and
immunological strategies to reduce HIV - 1 persistence, and on evaluating such interventions in clinical
studies.
In this way, in - depth
immunological monitoring, genetic and proteomic analyses, and biomarker discovery from patient samples guides further laboratory investigation, where mechanistic
studies can be designed and animal modeling performed.
Current
studies focus mainly on two receptor systems - the mast cell surface receptor, FcεRI, and the receptor for epidermal growth factor that operate in
immunological and cell proliferation responses.
Therefore the group: i) characterizes the specificity of these antibody responses to identify relevant targets for a vaccine; ii) developes new approaches to test antibody responses; and iii) adoptes the
immunological analysis in preclinical (in rabbits and macaques) and clinical vaccines
studies to identify predictive signatures for the development and prioritization of new HIV - 1 vaccine candidates.
Examples include a series of
studies to document persistent microchimerism of donor cells in transfusion recipients, with particular focus on mechanisms and clinical relevance of donor stem cell microchimerism in transfused trauma patients, and the
immunological mechanisms and prevention of transfusion - related acute lung injury (TRALI) and alloimmunization.
Hu and his lab take biochemical, cell biological, and
immunological approaches to
study these questions in mouse tumor models and human cancer cells.
Our
study aims to gain insight in its pathogenesis, by evaluating multimodal MRI
studies in HIV - positive children versus healthy controls, and correlating alterations with neurocognitive,
immunological and pharmacological states.
Published
studies have suggested that T1D results from environmental triggers acting on genetically susceptible individuals and that microbial infection and their
immunological consequences are suspected to take part in the pathogenesis.
In addition, Dr. Marrack is
studying how alum improves
immunological memory and whether Bcl - 2 proteins, which affect a cell's lifecycle, are involved.