Sentences with phrase «studies of embryonic stem cells»

The new approach builds on information gleaned from developmental studies of embryonic stem cells (see story # 16) and one day may be used to create healthy replacements for harmed or diseased tissue.

Studies of embryonic stem cells revealed that NANOG protein levels can be lowered by a chemical process known as methylation, which involves putting a methyl group chemical tag on a protein's messenger RNA (mRNA) precursor.

Zernicka - Goetz's research could also lead to important advancements in the study of embryonic stem cell therapy applications.

He joined the Gladstone Institutes as a postdoctoral fellow in 1993 where his early research into proteins involved in cholesterol metabolism led him to the study of embryonic stem cells and differentiation.

Not exact matches

However, embryonic stem cells remain the «gold standard,» and studies of all types of stem cells should continue in parallel for the foreseeable future.»

The study results were found using mouse embryonic stem cells, which are good cell models for the study of processes seen in human stem cells.

«I think this is the best option we have ever had,» says Renee Reijo Pera, director of Stanford University's Center for Human Embryonic Stem Cell Research and Education in California, who wasn't involved in the study.

Some of the researchers at the centre will study the differentiation of stem cells into other cell types, one group by using human embryonic stem cell biology and another by studying early embryo development.

For example, animal studies have shown that neurons derived in the lab from human embryonic stem cells improve Parkinson's symptoms; however, any residual stem cells associated with those neurons could form masses of unwanted cells.

There have also been safety concerns confronting all hESC studies, including worries that the embryonic stem cells could proliferate out of control.

The only previous demonstration — by researchers led by Shou - Wei Ding, PhD, a professor of Plant Pathology and Microbiology at UC Riverside and co-corresponding author of the current study — was done in embryonic stem cells and in newborn mice.

To see whether cancer stem cell renewal involves a chain of events similar to that used by embryonic stem cells, and whether the process was affected by oxygen levels, Semenza and graduate student Chuanzhao Zhang focused their studies on two human breast cancer cell lines that responded to low oxygen by ramping up production of the protein ALKBH5, which removes methyl groups from mRNAs.

Mouse embryonic stem cells, reported in 1981 by Martin Evans, Matthew Kaufman, and Gail Martin, have allowed scientists to generate genetically customized strains of mice that have revolutionized studies of organismic development and immunity and have provided countless models of human disease.

«Use of induced pluripotent stem cell (iPSC) technology» — which involves taking skin cells from patients and reprogramming them into embryonic - like stem cells capable of turning into other specific cell types relevant for studying a particular disease — «makes it possible to model dementias that affect people later in life,» says senior study author Catherine Verfaillie of KU Leuven.

«It's just presumed that they have fewer capabilities than embryonic stem cells,» says Bill Lowry, a coauthor of the study.

This study provides experimental evidence which shows the important role of RNA levels in the controlling the fate of embryonic stem cells, and shows an understanding of RNA's ability to differentiate stem cells at the molecular level.

Eva Mezey, a stem cell biologist at the National Institutes of Health who published one of the transdifferentiation studies and stands by the effect, notes that embryonic cells are naturally more versatile than adult stem cells.

In a response to Friday's decision, NIH spokesperson John Burklow said NIH doesn't set aside fixed amounts of money for studying adult or embryonic stem cells, but instead makes award decisions based on scientific merit and relevance to NIH's priorities.

«New tools to study the origin of embryonic stem cells.»

«We studied how the Sox2 gene is turned on in mice, and found the region of the genome that is needed to turn the gene on in embryonic stem cells,» said Professor Jennifer Mitchell of U of T's Department of Cell and Systems Biology, lead invesigator of a study published in the December 15 issue of Genes & Development.

This discovery by the scientists at the CRG provides an insight into stem cell - forming molecular mechanisms, and is therefore of great interest for studies on the early stages of life, during embryonic development.

Thorough study of changes in the gene activity regulation mechanism showed that reprogrammed and embryonic stem cells are similar.

The lead author of the Minnesota study, Yuehua Jiang, counters that the same reservations apply to embryonic stem cells: «Are they cultured naturally?»

A new study in Nature Genetics identifies a specific population of pluripotent embryonic stem cells that can reprogram to totipotent - like cells in culture.

UC announced yesterday that it is the first research institution to seek to «intervene,» or become a party in the case, in which the government is appealing a lower court's ruling that National Institutes of Health (NIH) funding to study human embryonic stem cells (hESCs) violates federal law.

«Studies on embryonic development greatly benefit from the culture system of embryonic stem cells and, more recently, induced pluripotent stem cells.

Studying mouse embryonic stem cells, they removed Grb2, a protein essential to the ability of the stem cell to transform into other cell types, from the cells.

Shortly after his inauguration, Bush ordered a review of the current National Institutes of Health (NIH) policy, which allows the funding of embryonic stem cell studies as long as researchers receive the cells from privately funded researchers who have derived them in accord with a set of ethical guidelines (ScienceNOW, 23 August 2000).

The study, published today in the journal Cell Stem Cell and led by Dr. Shunsuke Ishii from RIKEN, sought to identify the molecule in the mammalian oocyte that induces the complete reprograming of the genome leading to the generation of totipotent embryonic stem ceStem Cell and led by Dr. Shunsuke Ishii from RIKEN, sought to identify the molecule in the mammalian oocyte that induces the complete reprograming of the genome leading to the generation of totipotent embryonic stem cestem cells.

In a series of studies published since 2009, researchers in Wells» laboratory used human pluripotent stem cells (hPSCs) to grow embryonic - stage small intestines with a functioning nervous system, and the antrum and fundus regions of the human stomach.

Expanding from their previous studies with mice, the researchers first established that under specific conditions, culturing human embryonic stem cells with fibroblast growth factor 2 (FGF2) leads to neural differentiation particular to the midbrain / hindbrain region — the location of the cerebellum — within three weeks, and the expression of markers for the cerebellar plate neuroepithelium — the part of the developing nervous system specific for the cerebellum — within five.

Other potential uses of embryonic stem cells include investigation of early human development, study of genetic disease and as in vitro systems for toxicology testing.

The study, «Directed network wiring identifies a key protein interaction in embryonic stem cell differentiation,» was supported by the National Institutes of Health.

Adult and embryonic stem cells are complementary subjects of research and studying them side by side offers the greatest potential to rapidly generate new therapies.

The answer to this question comes from the lab of Marcel Leist (University of Konstanz, Germany) and their studies employing a defined and controllable in vitro system of post-mitotic murine astrocytes generated from embryonic stem cells (mAGES)[1].

What Collins does not say, however, is that the new NIH guidelines also allow for federal funds to be used in studying new human embryonic stem cell lines that are created (by private entities, of course) beyond the 700 currently in existence.

Yamanaka and Takahashi began their search by studying embryonic stem cells in the hope of identifying the genes that underlie essential stem cell characteristics, such as pluripotency and proliferation, a cell's ability to replicate itself.

That study found that since MSCRF first began awarding grants in 2007, its pattern of giving shifted over the years from strongly favoring projects focusing on ethically contentious human embryonic stem cell research (hESCR) to projects focusing on ethically non-contentious adult stem cells and other non-embryonic stem cell research.

Enriched population of PNS neurons derived from human embryonic stem cells as a platform for studying peripheral neuropathies.

Embryonic, hematopoietic and mesenchymal stem cells have been successfully employed for tolerance induction in a variety of rodent and large - animal studies 60, 61, 62.

«Discovery of a gene that could convert human embryonic stem cells into myocardial cells would be golden,» said Didier Stainier, PhD, UCSF assistant professor of biochemistry and biophysics, the senior author of the UCSF study and a pioneer in the study of heart development in the transparent zebrafish embryo.

At present, there are no embryonic stem - cell treatments approved by the US Food and Drug Administration, and most human studies of such therapies have shown unremarkable results.

While embryonic stem cells are widely studied, a lesser known, but still significant, population of stem cells also resides within the early developing embryo: trophoblast stem cells (TSCs).

Studies of stable cell maintenance are being conducted in leukemia stem cells, hematopoietic stem cells, and mouse embryonic stem cells.

Recently, his lab used induced pluripotent stem (iPS) cells — adult cells made to act like embryonic stem cells — made from skin cells of patients carrying apoE4, or other mutations related to Alzheimer's, to study their effects on the development, survival, and degeneration of human neurons.

Leading US research institutions may stop studying several federally - fundable linkurl: embryonic stem cell; https://www.the-scientist.com/blog/display/54749/ lines due to potential ethical problems surrounding the creation of the lines.

Pluripotent stem cells — those, like embryonic stem cells, that give rise to almost every type of cell in the body — can be converted into the different classes of retinal cells necessary for vision, according to a new, RPB - supported study from researchers at SUNY Upstate Medical University in Syracuse, N.Y.

When the studies of mitochondrial carryover were done in embryonic stem cells derived from ePNT blastocysts (to allow for more cell divisions during which instability could manifest), some stem cell lines displayed instability and an increase in mitochondrial DNA carryover with time.

Henk Stunnenberg, leader of one of the research groups that carried out the study and coordinator of both Heroic and the recently started High Impact Project BLUEPRINT, said: «The epigenetic make - up - a layer of regulatory instructions on top of the genome - of the pure embryonic stem cells shows remarkable and unexpected features, in particular with respect to developmental genes.

Embryonic stem (ES) cells are important tools in the study of gene function and may also become important in cell therapy applications.