Sentences with phrase «studies of human cells»

Researchers have found an anti-inflammatory effect of ginseng in test - tube studies of human cells.

In studies of human cells infected with the HIV virus, patentiflorin A had a much more significant inhibition effect on the RT enzyme.

Aguayo told TreeHugger that in studies of human cell cultures, potassium bromate has been seen to have a genotoxic effect, or in other words, causes damage to the cell's DNA.

Not exact matches

Available epidemiologic studies in humans have «not shown clear evidence of a relationship between cell phone use and cancer,» according to the National Cancer Institute, although this remains a topic of debate among researchers.

«We suspected that the young are most vulnerable because of their immature immune systems, but we didn't have a lot of hard evidence to show that before,» said study lead author Bo Hang, a Berkeley Lab staff scientist who previously found that thirdhand smoke could lead to genetic mutations in human cells.

The objects of his study range from a class of molecules that have the basic self - duplicating property of living things, through cells which suggest purely physical systems, through animals which give increasing evidence of having minds, to human beings in whom streams of consciousness seem to involve continual choices of action, at the opposite pole from control by impersonal laws of nature.

High dosages of reb A fed to rats reduced sperm production and increased cell proliferation in their testicles; however, another study using rats and humans demonstrated lack of reproductive toxicity.

«Animal studies and in - vitro studies with human cells have repeatedly shown that food - grade carrageenan causes gastrointestinal inflammation and higher rates of intestinal lesions, ulcerations, and even malignant tumors.»

There have been lots of cell and animal research, which prove that turmeric has a good influence on a number of illnesses and also several human studies have shown positive results as well.

This study built on previous research from the Sundrud lab, which showed that when TH17 cells entered the intestine in human tissue samples, they increased the expression of a gene called MDR1.

To create the effect of tobacco smoke on cells, Vaz, Baylin and their colleagues began their studies with human bronchial cells, which line the airways of the lungs, and grew them in a laboratory.

By studying human cancer cells and animal models of cancer in the lab, our researchers have shown that loss of PTEN leads to high levels of PI (3,4) P2, which could result in hyperactivation of AKT.

Sharon joined Anglister's lab for her master's project and Ph.D., studying the three - dimensional structure of a region in the HIV - 1 protein envelope that helps the virus enter human cells.

WASHINGTON — Tiny orbs of brain cells swirling in lab dishes may offer scientists a better way to study the complexities of the human brain.

Researchers there are examining the role of other signaling factory beyond BMP as well as conducting further studies using human cells and human scar tissue.

«Our research is the first to study Zika infection in a mouse model that transmits the virus in a way similar to humans,» explains Alysson R. Muotri, Ph.D., professor and director of the Stem Cell Program at UC San Diego and co-senior author of the study.

In the study, the researchers loaded a hydrogel — a half - inch disc made of a biodegradable sugar naturally found in the human body — with drugs that activate dendritic cells.

The study provides a new understanding of how, billions of years ago, the complex cell types that comprise plants, fungi, but also animals and humans, evolved from simple microbes.

Working with human breast tissue, the new study's authors attempted to induce EMT in normal cells; they figured they would just get fibroblasts, a type of connective tissue that is important in wound healing.

The team has already successfully repopulated pig kidneys with human cells, but Ott says further studies are vital to guarantee that the pig components of the organ do not cause rejection when transplanted into humans.

The study results were found using mouse embryonic stem cells, which are good cell models for the study of processes seen in human stem cells.

«I think this is the best option we have ever had,» says Renee Reijo Pera, director of Stanford University's Center for Human Embryonic Stem Cell Research and Education in California, who wasn't involved in the study.

RNAScope ISH was developed by Advanced Cell Diagnostics (ACD) Inc., initially for studies of gene expression in animal (and especially human) tissues.

«Cultural revolution in the study of the gut microbiome: Human gut - on - a-chip technology used to co-culture gut microbiome, human intestinal cells could lead to new therapies for inflammatory bowel diseases.&rHuman gut - on - a-chip technology used to co-culture gut microbiome, human intestinal cells could lead to new therapies for inflammatory bowel diseases.&rhuman intestinal cells could lead to new therapies for inflammatory bowel diseases.»

Dr Tomi Pastinen, senior author on the second study, from McGill University said: «We have created an expansive, high - resolution atlas of variations that deepens our understanding of the interplay between the genetic and epigenetic machinery that drives the three primary cells of the human immune system.

A study published by Cell Press October 16th in Cell now reveals that gut microbes in mice and humans have circadian rhythms that are controlled by the biological clock of the host in which they reside.

«Before this study, it was not known if it is possible to produce sufficient numbers of these cells and successfully use them to remuscularize damaged hearts in a large animal whose heart size and physiology is similar to that of the human heart,» said Dr. Charles Murry, UW professor of pathology and bioengineering, who led the research team that conducted the experiment.

Some of the researchers at the centre will study the differentiation of stem cells into other cell types, one group by using human embryonic stem cell biology and another by studying early embryo development.

Adding stem cells from human bone marrow to a broken diabetic bone enhances the repair process, increasing the strength of the newly formed bone, according to a laboratory - based study presented at the European Congress of Endocrinology in Dublin.

For example, animal studies have shown that neurons derived in the lab from human embryonic stem cells improve Parkinson's symptoms; however, any residual stem cells associated with those neurons could form masses of unwanted cells.

85 Billion Estimated number of cells in the human brain that are not neurons, according to a 2009 study by Brazilian neuroscientists.

This proof - of - principle study shows «for the first time... that human iPS cells can be used to model a diverse range of inherited diseases in adult cells,» the authors wrote in their paper, published online in The Journal of Clinical Investigation August 25.

If norovirus also targets tuft cells in humans, «maybe that's the cell type we need to be treating,» says study coauthor Craig Wilen, a physician scientist at the Washington University School of Medicine in St. Louis.

Published in Molecular Neurobiology, the study led by Dr Elodie Siney under the supervision of Dr Sandrine Willaime - Morawek, Lecturer in Stem Cells and Brain Repair at the University, analysed how enzymes called ADAMs affect the movement and function of the human tumor cCells and Brain Repair at the University, analysed how enzymes called ADAMs affect the movement and function of the human tumor cellscells.

In their latest study, they tested compounds against cells from nine different types of human cancer, including common types affecting blood, colon, breast, prostate, ovaries, kidneys, and lungs.

Another problem is that in its July 2009 Guidelines on Human Stem Cell Research, NIH spelled out specific requirements about embryo donation for newly derived lines, says Pilar Ossorio, a legal scholar who studies research ethics at the University of Wisconsin Law School.

Bloch's colleagues at the National Institute of Environmental Health Sciences tested the oils in gene expression studies on lab - grown human breast cancer cells and found that they could mimic estrogens, the primary female sex hormones, and inhibit androgens, the primary male sex hormones.

The study involved laboratory cell lines of human leukemia and mouse models of the disease.

Engineered human immune cells can vanquish a deadly pediatric brain tumor in a mouse model, a study from the Stanford University School of Medicine has demonstrated.

«These results provide the basis for the potential implementation of 5 - LO - inhibitors as stem cell therapeutic agents for a sustained AML cure, although this must be investigated further in preclinical and clinical studies in humans,» explains Dr. Ruthardt.

Meanwhile, recent human studies indicate that aging is associated with an increase in somatic mutations in the hematopoietic system, which gives rise to blood cells; these mutations provide a competitive growth advantage to the mutant hematopoietic cells, allowing for their clonal expansion — a process that has been shown to be associated with a greater incidence of atherosclerosis, though specifically how remains unclear.

The new rules state that stem cells can be used if they are part of a study approved by the federal government, or if the protocol has been approved by an Institutional Review Board (IRB) that provides ethical review for research involving human volunteers.

These techniques include: human tissue created by reprogramming cells from people with the relevant disease (dubbed «patient in a dish»); «body on a chip» devices, where human tissue samples on a silicon chip are linked by a circulating blood substitute; many computer modelling approaches, such as virtual organs, virtual patients and virtual clinical trials; and microdosing studies, where tiny doses of drugs given to volunteers allow scientists to study their metabolism in humans, safely and with unsurpassed accuracy.

In this study, the Hiroshima University researchers developed an animal model using severely immunodeficient mice whose livers were partially populated with human cells, in order to reconstruct elements of the human immune system.

FRESH insight into prostate cancer has come in a study showing that the mitochondrial DNA of human prostate cancer cells is riddled with mutations.

This is the finding of a study in both mice and human patients led by researchers at NYU Langone Medical Center and published online June 9 in the journal Cell.

«Due to the inhibitory function of Treg cells, people have been trying to use these cells for therapy in human autoimmune diseases or transplantation,» explains professor Yun Cai Liu, Ph.D., who led the current study.

Professor Ali Tavassoli, who led the study with colleague Dr. Ishna Mistry, explains: «In an effort to better understand the role of HIF - 1 in cancer, and to demonstrate the potential for inhibiting this protein in cancer therapy, we engineered a human cell line with an additional genetic circuit that produces the HIF - 1 inhibiting molecule when placed in a hypoxic environment.

Pre-clinical studies have shown it to be effective in eliminating a number of different kinds of cancers cells, including cancer stem cells from human breast cancer patient biopsies.

While mouse models have traditionally been used in studying the genetic disorder, Deng said the animal model is inadequate because the human brain is more complicated, and much of that complexity arises from astroglia cells, the star - shaped cells that play an important role in the physical structure of the brain as well as in the transmission of nerve impulses.