His team has developed statistical methods, computational algorithms and software that facilitate quick, accurate analysis of genetic
studies of human disease.
The study of viruses far removed from human concerns has brought to light powerful tools for
the study of human disease.
Last year the National Institutes of Health announced plans to put some 180 ex-Coulston chimps currently housed at the Alamogordo Primate Facility back in service, to rejoin the roughly 800 other chimps that serve as subjects for
studies of human diseases, therapies and vaccines in the U.S., which is the only country apart from Gabon to maintain chimps for this purpose.
Such ease of use will likely encourage the use of more animal models in
the study of human diseases, says Rhonda Wiler, a geneticist at biotech giant Genentech in San Francisco, California, who co-chairs the Roundtable on Science and Welfare in Laboratory Animal Use (which organized the workshop).
Having shared the environment with humans ever since its appearance, the dog has been exposed to similar pathogens, and therefore represents an important model system for
the study of human diseases.
The INFRAFRONTIER mission: ◊ to shape the European Research Area in the field of mouse functional genomics and thereby make an important contribution to
the study of human disease.
BETHESDA, Md., Wed., Oct. 5, 2005 - The National Institutes of Health (NIH) today announced contracts that will give researchers unprecedented access to two private collections of knockout mice, providing valuable models for
the study of human disease and laying the groundwork for a public, genome - wide library of knockout mice.
«That shows that, indeed, the mouse is a good system to use in
the study of human disease.
My goal over the past several years has been to adapt new advanced optical imaging technologies to
the study of human diseases, and where we lack tools to study specific aspects of human vision diseases, to develop new ones to fill in the gaps.
The use of NHP in biomedical research is justified in
the studies of human diseases, to learn more about their causal pathways, their development, their infectiveness and to develop therapeutic and preventive strategies.
His research interests include the development of advanced ophthalmic imaging devices and their application to
the study of human diseases such as glaucoma and age - related macular degeneration.
International Journal of Medical Sciences publishes papers of significance in areas of basic medical sciences and clinical research related to
the studies of human diseases.
Today, nuclear cloning is one of the essential tools in Dr. Jaenischs laboratory
studies of human diseases, including his groundbreaking work on the nature and potential treatment of cancer.
Career goals: My goal is to become a scientific researcher involved in the genetic and functional
studies of human diseases.
CELPHEDIA networks aims to develop transverse inter-species approaches (rodents with the mouse as a leader, non-human primates and non mammalians including aquatic vertebrates), at the level of both the technology and
the study of human diseases, but also to harmonise scientific protocols and processes.
«We are very pleased to be able to offer human whole genome sequencing of up to 15,000 individual genomes per year, enabling scientists to perform internationally competitive
studies of human diseases and evolution» says Ann - Christine Syvänen at NGI in Uppsala.
The medical researchers noted that mice are considered a good surrogate for
studies of human diseases and conditions.
Not exact matches
«There are a lot
of naturally occurring dog
diseases — especially psychiatric
diseases — that are very similar to
human diseases,» Hyun Ji Noh, a geneticist at the Broad Institute and the lead author on the
study, told Business Insider.
«So to me it was sort
of natural to put dog
studies in the context
of human disease.»
Systems science is an interdisciplinary field that
studies how the interaction
of factors produces outcomes — how the causes and consequences
of events can, taken together, form the basis for everything from a
disease epidemic, to a pattern
of human behavior.
Twenge and Campbell are drawing here on research from the so - called positive psychology movement, which recently has attempted to shift the focus
of psychological research away from
disease and disorder to a
study of the character strengths that make for happiness and
human flourishing.
Some
of the marketing material highlighted in Lion's cross claim includes: «A2 will improve
human health through the consumption
of a2 dairy milk products», «
studies suggest that milk containing only the A2 type
of protein may benefit you and your family if you're concerned with certain allergies, immune function or digestive wellbeing» and «there is significant evidence to suggest that beta casein A1 may be a primary risk factor for heart
disease in adult men and also be involved in the progression
of insulin dependent diabetes in children... Beta casein A1... is the most powerful risk factor ever discovered.»
«Future
studies need to determine the health effects
of these cocoas in models
of human disease and to evaluate the consumer acceptability
of the cocoas as part
of a chocolate product.»
so often they just look at potential markers — but those don't always equate to
diseases)- what was the health
of the those being
studied - I'm assuming the test subjects were people, but other
studies done on animal subjects might not be as reliable as those done on
humans.
Numerous
studies have shown the benefits
of providing
human milk to newborn babies and young infants, which include better tolerance
of feeding, reduced gastrointestinal
disease, and improved intelligence.
Funding / Support: The Infant Feeding Practices
Study II was funded by the Food and Drug Administration, Centers for
Disease Control and Prevention, Office
of Women's Health, National Institutes
of Health, and Maternal and Child Health Bureau in the US Department
of Health and
Human Services.
Research in the United States, Canada, Europe, and other developed countries, among predominantly middle - class populations, provides strong evidence that
human milk feeding decreases the incidence and / or severity
of diarrhea,1 - 5 lower respiratory infection,6 - 9 otitis media,3,10 - 14bacteremia, 15,16 bacterial meningitis, 15,17 botulism, 18 urinary tract infection, 19 and necrotizing enterocolitis.20, 21 There are a number
of studies that show a possible protective effect
of human milk feeding against sudden infant death syndrome,22 - 24insulin - dependent diabetes mellitus,25 - 27 Crohn's
disease, 28,29 ulcerative colitis, 29 lymphoma, 30,31 allergic diseases,32 - 34 and other chronic digestive diseases.35 - 37 Breastfeeding has also been related to possible enhancement
of cognitive development.38, 39
less than or equal to lamivudine Acquired Immune Deficiency Syndrome Antiretroviral therapy, usually means 1 - 2 drugs, used in early
studies Antiretroviral zidovudine (also known as ZDV) Breastfeeding Baby Friendly Hospital Initiative Breastfeeding and HIV International Transmission
Study Combined antiretroviral therapy Centers for
Disease Control and Prevention Deoxyribonucleic Acid Exclusive Breastfeeding Enzyme Linked Immunosorbent Assay Food and Agrigulture Organization Fixed dose combination ART, e.g., lamividine, stavudine, and nevirapine Highly Active Antiretroviral Therapy, 3 or more drugs for more effective treatment used in later
studies Human Immunodeficiency virus International Atomic Energy Agency Infant feeding Infant and young child feeding Lopinavir cubic millimetre Mother - to - Child Transmission
of HIV Non-governmental organization Nevirapine Polymerase Chain Reaction People Living with HIV Prevention
of Mother - to - Child Transmission Replacement Feeding Ritonavir Ribonucleic acid, one
of the three major macromolecules (along with DNA and proteins) that are essential for all known forms
of life single dose NVP United Nations Agencies Joint United Nations Programme on HIV / AIDS United Nations Population Fund United Nations Commissioner for Refugees United Nations Children's Fund U.S. Agency for International Development World Alliance for Breastfeeding Action United Nations World Food Programme World Health Assembly WHO 2010 Guidelines on HIV and infant feeding World Health Organization Zidovudine (same drug as AZT)
No
studies have compared exclusive prolonged hydrolyzed (including both partially and extensively hydrolyzed formulas) formula feeding (more than 3 days) with
human milk feeding on the incidence
of atopic
disease.
Studies have shown that a protein in
human milk aids in brain development, and breast - fed babies are less likely to get gastrointestinal infections and diarrhea, respiratory and ear infections or more serious
diseases such as pneumonia, and there is a lower risk
of Sudden Infant Death Syndrome.
Physiologic sleep
studies have found that breastfed infants are more easily aroused from sleep than their formula - fed counterparts.247, 248 In addition, breastfeeding results in a decreased incidence
of diarrhea, upper and lower respiratory infections, and other infectious
diseases249 that are associated with an increased vulnerability to SIDS and provides overall immune system benefits from maternal antibodies and micronutrients in
human milk.250, 251 Exclusive breastfeeding for 6 months has been found to be more protective against infectious
diseases compared with exclusive breastfeeding to 4 months
of age and partial breastfeeding thereafter.249
The charity said this was «particularly concerning» as most
of these experiments
studied human diseases which do not exist in non-
human primates, such as Parkinson's
Disease, and this they suggested «significantly challenges» the validity
of the tests.
Forward - thinking scientists, many with funding from PETA and its international affiliates, are developing methods for
studying diseases and testing products that don't require the use
of animals and are actually relevant to
human health.
As part
of the
study, researchers found that mice engineered to develop symptoms
of human inflammatory
disease, and which also lacked the ATG16L1 gene, developed gut damage.
Of the thousands of ancestral variants reintroduced into modern humans, only 41 have been linked in genetic studies to diseases, such as skin conditions and neurological and psychiatric disorders, he sai
Of the thousands
of ancestral variants reintroduced into modern humans, only 41 have been linked in genetic studies to diseases, such as skin conditions and neurological and psychiatric disorders, he sai
of ancestral variants reintroduced into modern
humans, only 41 have been linked in genetic
studies to
diseases, such as skin conditions and neurological and psychiatric disorders, he said.
A
study by researchers at the University
of Chicago Medicine shows that when mice that are genetically susceptible to developing inflammatory bowel
disease (IBD) were given antibiotics during late pregnancy and the early nursing period, their offspring were more likely to develop an inflammatory condition
of the colon that resembles
human IBD.
Molecular biologist Christina Warinner
studies calculus, or fossilized dental plaque, which contains a trove
of genetic clues to past
human diet and
disease.
High total and saturated fat intake were associated with greater risk
of estrogen receptor - and progesterone receptor - positive (ER+PR +) breast cancer (BC), and
human epidermal growth factor 2 receptor - negative (HER2 --RRB-
disease, according to a new
study published April 9 in the Journal
of the National Cancer Institute.
Researchers from Instituto de Medicina Molecular (iMM) Lisboa have created a chimera virus that allows the
study of molecules to treat cancers caused by
human herpes virus infection in mice models
of disease.
Ocean seagrass meadows reduce bacteria unhealthful to
humans and marine organisms by up to 50 %, a new
study shows, and they also decrease the likelihood
of disease in coral reefs by half.
Studies on the origins
of BSE — a fatal
disease marked in the early stages by loss
of balance — gained urgency with the 1996 emergence in
humans of the BSE - like new variant Creutzfeldt - Jakob
disease (nvCJD).
«Much like the spread
of human disease in populated areas, urban centers can foster increases in multiple
disease types in wild animals,» said McGraw, senior author
of the
study.
The
study of these highly unusual but devastating prion
diseases has to date been thwarted by a lack
of animal models that faithfully mimic the
disease processes in
humans.
In this
study, published in the Journal
of the American College
of Cardiology, researchers also identified six further variants in the
human genome that occur more frequently in a coronary artery
disease (CAD).
«Cultural revolution in the
study of the gut microbiome:
Human gut - on - a-chip technology used to co-culture gut microbiome, human intestinal cells could lead to new therapies for inflammatory bowel diseases.&r
Human gut - on - a-chip technology used to co-culture gut microbiome,
human intestinal cells could lead to new therapies for inflammatory bowel diseases.&r
human intestinal cells could lead to new therapies for inflammatory bowel
diseases.»
Reductions in biodiversity from illegal wildlife trade can have other substantial negative
human health impacts, including the loss
of potential sources
of pharmaceuticals, experimental models for
studying disease, crop pollination and micronutrients for
humans lacking alternative sources
of protein.
«New models advance the
study of deadly
human prion
diseases.»
A recent
study published in Annals
of Neurology reports that healthy
human tissue grafted to the brains
of patients with Huntington's
disease in the hopes
of treating the neurological disorder also developed signs
of the illness, several years after the graft.
The new
study supports the theory
of antibody - dependent enhancement in
humans, says Anna Durbin, an infectious
diseases physician at Johns Hopkins Bloomberg School
of Public Health.
Even the new
studies clashed somewhat: Unlike the UCSF
study, the German research found no major differences between the overall microbiomes
of twins with and without MS. Finally, mouse models
of MS are not perfect mimics
of the
human disease, and mouse immune systems aren't identical to people's.