Sentences with phrase «studies of the human genome»

Ascertainment bias in studies of human genome - wide polymorphism.

Ascertainment bias in studies of human genome - wide polymorphism Clark, A. G., M. J. Hubisz, C. D. Bustamante, S. H. Williamson et al. 2005.

Recent studies of the human genome have identified genetic regions associated with autoimmune diseases such as type 1 diabetes.

Not exact matches

The entire genome of the tiny nematode (Caenorhabditis elegans) also has been sequenced as a ta - ngen = tial study to the human genome project.

J. Craig Venter, the geneticist who decoded the human genome, has been absorbed in the study of virii for a number of years.

Maybe on your scientific journey you'll see what the leader of the Human Genome Project saw and convert BECAUSE of your scientific studies.

The most compelling comes from the study of genes, especially now that the Human Genome Project has been completed and the genomes of many other species being constantly mapped.

This is in essence, the sort of argument to which we incline most readily when we worry about recent advances in the study and manipulation of genes and about the implications of the Human Genome Initiative.

«Our study shows that epigenetic drift, which is characterized by gains and losses in DNA methylation in the genome over time, occurs more rapidly in mice than in monkeys and more rapidly in monkeys than in humans,» explains Jean - Pierre Issa, MD, Director of the Fels Institute for Cancer Research at LKSOM, and senior investigator on the new study.

«Most of the human genome sequence is now known, but we still don't know what most of these sequences mean,» said Sheng Zhong, bioengineering professor at the UC San Diego Jacobs School of Engineering and the study's lead author.

«Our work demonstrates that the generation of genome sequences from a large number of archaic human individuals is now technically feasible, and opens the possibility to study Neandertal populations across their temporal and geographical range,» says Janet Kelso, the senior author of the new study.

EPFL scientists have carried out a genomic and evolutionary study of a large and enigmatic family of human proteins, to demonstrate that it is responsible for harnessing the millions of transposable elements in the human genome.

In this study, published in the Journal of the American College of Cardiology, researchers also identified six further variants in the human genome that occur more frequently in a coronary artery disease (CAD).

But everything we're learning from the human and animal genome projects, about the conservation of neurochemistries and the neuroanatomies, all of this points me to the conclusion that we are learning about ourselves when we study these little critters.»

Most of the rechristened genes were identified by geneticists studying the fruit fly; when equivalent genes were later found in the human genome, researchers simply continued using the name of the fruit fly gene to avoid confusion.

The study, the culmination of more than 10 years of research and published online in the journal Arthritis & Rheumatology in June, discovered virus - like elements within the human genome linked to the development of two autoimmune diseases: lupus and Sjogren's syndrome.

«This study shows us how far we are from a comprehensive understanding of the human genome.»

This avenue of research is still new, since we have only recently begun to decode the mysteries of the human genome, but studies are emerging every year.

Studies over the past decade have revealed that the complexity of the genome, and indeed almost every aspect of human biology, is far greater than was previously thought.

But when she got an offer to start her own research group studying the evolutionary history of Latin Americans at Mexico's new human genome research institute, less than 3 years after finishing her Ph.D., she couldn't turn it down.

A new study suggests that epigenetic effects — chemical modifications of the human genome that alter gene activity without changing the DNA sequence — may sometimes influence sexual orientation.

In any case, however, high quality nuclear genome data from more than one individual would be necessary to fully investigate this proposed wave of human migration out of Africa, and is an intriguing area for future study.

The study underlines the significance of southern African archaeological remains in defining human origins, and is published in the journal Genome Biology and Evolution, now online.

«Notably, both LbCpf1 and AsCpf1 targeted to a certain site cleaved only the on - target site in the entire human genome» said KIM Daesik, one of first authors of the study (Fig. 1b).

The study «tells us something that we may have been missing in the past,» says Jan - Fang Cheng of the Human Genome Center at Lawrence Berkeley National Laboratory in California.

«This is the first genome - wide data on prehistoric humans from the hot tropics, and was made possible by improved methods for preparing skeletal remains» says Ron Pinhasi at University College Dublin, a senior author of the study.

«This study gives deep new insights into the life of a parasitic fluke in the human bile duct, and was enabled by the development of an exciting new genome assembly tool called OPERA - LG in our lab.

Studies comparing the mouse and human sequences that accompany the mouse genome in the journal Nature suggest it provides plenty of new leads in biology and disease.

«Genomes from these more remote populations really can tell us a huge amount about human evolutionary history,» says Evelyn Jagoda, a Harvard University evolutionary genetics Ph.D. student and co-author of one of the studies.

The other part of the atlas was a physical map of the genome created by a group of researchers from the Center for the Study of Human Polymorphism in Paris.

In 2002 a student in Christiano's lab was studying the Human Genome Project database and noticed an unnamed region where Christiano had predicted the human version of the lanceolate gene would reHuman Genome Project database and noticed an unnamed region where Christiano had predicted the human version of the lanceolate gene would rehuman version of the lanceolate gene would reside.

Surprisingly, the study also found that the genomes of Latino individuals are a uniquely powerful resource for assembling maps of the human genome.

The new study shows that the synthetic compound is capable of inhibiting the activities of several DNA - processing enzymes, including the «integrase» used by the Human Immunodeficiency Virus (HIV) to insert its genome into that of its host cell.

The study, «VlincRNAs controlled by retroviral elements are a hallmark of pluripotency and cancer» found that novel non-coding parts of the human genome known as vlincRNAs (very long intergenic, non-coding RNAs) triggered by ancient viruses, participate in the biology of stem cells, and in the development of cancer.

Results: The study revealed three novel variations in the human genome that increase risk of Fuchs dystrophy.

About 1,000 species normally live on the surface of human skin, according to a recent study by the National Human Genome Research Instihuman skin, according to a recent study by the National Human Genome Research InstiHuman Genome Research Institute.

The observational study published in Genome Biology utilized publicly available and unpublished data sets to find 2,147 vlincRNAs that cover 10 percent of the human genome, suggesting that their production is a common, yet undiscovered, feature of humaGenome Biology utilized publicly available and unpublished data sets to find 2,147 vlincRNAs that cover 10 percent of the human genome, suggesting that their production is a common, yet undiscovered, feature of humagenome, suggesting that their production is a common, yet undiscovered, feature of human DNA.

The study was led by researchers at the National Institute of Allergy and Infectious Diseases (NIAID) and the National Human Genome Research Institute (NHGRI), both part of NIH.

The research team from the National Human Genome Research Institute (NHGRI) and the National Cancer Institute (NCI), both parts of NIH, extended their recent genome sequencing study of skin bacteria, using DNA sequencing techniques optimized for identifying Genome Research Institute (NHGRI) and the National Cancer Institute (NCI), both parts of NIH, extended their recent genome sequencing study of skin bacteria, using DNA sequencing techniques optimized for identifying genome sequencing study of skin bacteria, using DNA sequencing techniques optimized for identifying fungi.

Only about 100 of the tens of thousands of genes that make up the human genome are marked with these gender - specific stamps, subsequent studies showed.

So our focus will be to study the genome through the transcripts in biological systems, to understand the genetic architecture of Pan-Asian populations, and finally to focus on the intersect between genomics and human medicine.

Neanderthal genetic material is found in only small amounts in the genomes of modern humans because, after interbreeding, natural selection removed large numbers of weakly deleterious Neanderthal gene variants, according to a study by Ivan Juric and colleagues at the University of California, Davis, published November 8th, 2016 in PLOS Genetics.

Most of those studies have focused on the portion of the human genome that encodes protein — a fraction that accounts for just 2 percent of human DNA overall.

«We've been able to look at how newly discovered genetic risks relate to the life course of asthma at an unprecedented level of resolution,» said Daniel Belsky, a postdoctoral fellow at the Duke Institute for Genome Sciences & Policy and the Center for the Study of Aging and Human Development.

The study, appearing online in eLife, was conducted by researchers at NIH's Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) and National Human Genome Research Institute and the Japanese National Institute of Genetics.

«Having the genome sequence is like having part of the instruction manual,» says study author Richard Wilson of Washington University in Saint Louis (W.U.), echoing the famous 2000 comment of then Human Genome Project leader Francis Collins, who called knowledge of our genome a «glimpse of our instruction book.&genome sequence is like having part of the instruction manual,» says study author Richard Wilson of Washington University in Saint Louis (W.U.), echoing the famous 2000 comment of then Human Genome Project leader Francis Collins, who called knowledge of our genome a «glimpse of our instruction book.&Genome Project leader Francis Collins, who called knowledge of our genome a «glimpse of our instruction book.&genome a «glimpse of our instruction book.»

Two studies presented at the Biology of Genomes meeting in Cold Spring Harbor, New York, last week show how human genomes have changed over centuries or decades, charting how since Roman times the British have evolved to be taller and fairer, and how just in the last generation a gene that favors cigarette smoking led to early death in some Genomes meeting in Cold Spring Harbor, New York, last week show how human genomes have changed over centuries or decades, charting how since Roman times the British have evolved to be taller and fairer, and how just in the last generation a gene that favors cigarette smoking led to early death in some genomes have changed over centuries or decades, charting how since Roman times the British have evolved to be taller and fairer, and how just in the last generation a gene that favors cigarette smoking led to early death in some groups.

With the advent of genome engineering, scientists are now introducing hundreds of different human mutations in other species to study their effects and develop new drugs.

In keeping with previous studies comparing much smaller portions of the chimp and human genomes, the new comparison shows incredible similarity between the genomes.

«It's essential to have all of the great ape genomes in order to understand the features of our own genome that make humans unique,» says Gregory Wray, an evolutionary biologist at Duke University in Durham, North Carolina, who was not involved in the study.