Sentences with phrase «studies on gene»

First academic GLP center for performing biodistribution, toxicology / tumorigenicity and validation studies on gene and cell therapy products.

And plants are very well suited for studies on gene flow because individuals are stationary yet pollen and seeds are mobile.

Studies on genes, brain structures and hormones have failed to identify a clear link between, on one hand, differences at birth between the sexes and, on the other, particular behaviour.

ASCB President Don Cleveland of the University of California, San Diego, said his team just published an animal study on a gene silencing therapy for treating a form of Lou Gehrig's disease that they now hope to move to clinical studies.

In a comprehensive 2013 study on genes and obesity, researchers identified 32 different genes that can contribute to obesity.

Not exact matches

Instead of just focusing on human DNA, which in the other studies had yielded limited results, she looked at multiple sets of genes — and not just from humans.

June 19, 2013 — A Cornell University study offers further proof that the divergence of humans from chimpanzees some 4 million to 6 million years ago was profoundly influenced by mutations to DNA sequences that play roles in turning genes on and off.

Some researchers have looked into what role genes might have in our tendency to cheat, like last year's study on a certain variant of the dopamine gene DRD4 — and dopamine is the force behind our sexual drives, survival needs and pair - bonding behaviors.

Neuroscientists have over the past decade uncovered evidence, both in rodent and human studies, that parental caregiving, especially in moments of stress, affects children's development not only on the level of hormones and brain chemicals, but even more deeply, on the level of gene expression.

ANTI-CIO # 4: In a study performed on rats, rat mothers who were nurturing towards their rat babies (i.e. licked their babies often) produced more growth hormones and changed the chemistry of the DNA in certain genes involved in the offspring's stress response.

In fact, specific genes are studied for their impact on the threshold effect of some teratogens.

In the current study, Whitney, along with colleagues John Hinson, WSU professor of psychology, and Hans Van Dongen, director of the WSU Sleep and Performance Research Center at WSU Spokane, compared how people with different variations of the DRD2 gene performed on tasks designed to test both their ability to anticipate events and their cognitive flexibility in response to changing circumstances.

In February, the United Kingdom approved using the method on human embryos at the Francis Crick Institute in London, but only within a narrow capacity: Researchers can edit genes in non-viable human embryos for a limited period and only to study developmental biology related to in vitro fertilization.

The study sheds light on the mechanisms and adaptive significance of gene family evolution.

This study found that the interaction between these genomes and the implications on energy production is strong enough that the mitochondrial genome can alter which version of a gene is present in the nuclear genome.

Billions of data points on genes, proteins and other molecules are compiled in large files and systematically studied.

This study built on previous research from the Sundrud lab, which showed that when TH17 cells entered the intestine in human tissue samples, they increased the expression of a gene called MDR1.

In a study published in Neoplasia, researchers at the Washington University School of Medicine created a map showing which genes were switched on and off in different parts of the tumor, providing a «signature» of these switches throughout the genome.

The study, led by Dr Len Stephens and Dr Phill Hawkins and published today in the journal Molecular Cell, reveals why loss of the PTEN gene has such an impact on many people with prostate cancer, as well as in some breast cancers.

«Identifying which of these candidate genes actually causes variation in responses to cold snaps will give us the potential to understand whether evolution to climate change can occur in both wild and domesticated animals, allowing us to better predict which species or breeds will be «winners» and «losers» and to better mitigate the effects of anthropogenic climate change on a wide range of organisms from beneficial pollinators to invasive pests,» said Theodore Morgan an associate professor of evolutionary genetics in the Division of Biology at Kansas State University and senior author of the study.

Studies involving mice also helped to answer a key question: What turns on the activity of the per and tim genes in the first place?

«Our aim was to explore the effect of a more acidic ocean on every gene in the coral genome,» says study lead author Dr Aurelie Moya, a molecular ecologist with the ARC Centre of Excellence for Coral Reef Studies at James Cook University.

The UNC collaborators on the study team, led by Timothy C. Nichols, MD, performed gene therapy experiments using the well - established dog colony at their institution.

The study, published in Nature Structural and Molecular Biology, showed that a combination of genetics and epigenetics — factors that turn genes on or off — could explain how lactose intolerance develops over time.

A major study conducted on twins shows that environmental factors may be at least as important as genes in causing autism.

Biologists are studying whether genes could be switched on and off in plants depending on climatic conditions

Researchers Bence György and Cyrille Sage, first authors on the study, injected exo - AAV preloaded with the missing gene into the inner ears of mouse pups, shortly after birth.

Scientists are a step closer to discovering what determines the sex of Australia's iconic platypus and echidna, after an international study involving researchers from the University of Adelaide and UNSW Australia unravelled new genes contained on mammalian Y chromosomes.

The study results build on genetic and epigenetic basics, including that the blueprint for the human body is encoded in genes that direct the building of one or more proteins.

«CRISPR - on is a tool that will be very useful for studying many biological processes, particularly for studying gene functions and gene networks,» says Whitehead Founding Member Rudolf Jaenisch.

In the study, researchers worked with a mouse model that has a debilitating mutation on one of the exons of the dystrophin gene.

When the researchers took a closer look on the genomic areas pinpointed in the study, they noticed that most of them overlap with known genes.

A study published June 1 by Nature Communications reports scientists identify a new gene essential to this process, shedding new light on possible new therapeutic strategies.

But from the start, she also developed her own line of inquiry, winning a grant from the National Institute on Aging (NIA) to continue studying genes that govern senescence.

This study took a different approach — targeting a drug to a protein that controls how genes are turned on and off, early in the viral replication process.

A recent study in Ireland, for example, has uncovered evidence that famine survivors preferentially pass on a gene that helps the body store fat.

These results illustrate a useful approach for studying the effect of gene expression on cardiac contractility.

Molecular studies of gene expression during long - lasting synaptic plasticity related to memory storage initially focused on the identification of positive regulators.

I was looking around for insights when I came across the very thin literature on the genes that sculpt fruit fly bodies, including the study of spectacular mutants.

It, therefore, offers a new way to study the role of the environment on the expression of our genes.

Bloch's colleagues at the National Institute of Environmental Health Sciences tested the oils in gene expression studies on lab - grown human breast cancer cells and found that they could mimic estrogens, the primary female sex hormones, and inhibit androgens, the primary male sex hormones.

Other researchers on the study were Gene R. Stoner and Raynard Fung of the Salk Institute for Biological Studies.

After having conducted a large - scale study performed on cells from the umbilical cords of 204 newborns, the researchers from UNIGE demonstrate that DNA methylation may play both a passive and active role in gene regulation.

To more accurately reflect the mechanisms driving oligodendrogliomas, the researchers used RNA sequencing to study directly, on a single - cell level, gene expression in samples from six early - stage human tumors.

So far, researchers have mostly turned on genes with CRISPRa in cells growing in lab dishes, says Charles Gersbach, a biomedical engineer at Duke University not involved in the new study.

Then geneticists came on the scene, and they were studying small - scale differences within species based on mutations in genes.

«The rising level of integrons after 1990 in manured soil could indicate that through our efforts to reduce antibiotic resistance, we have unintentionally increased resistance gene exchange and more study is needed on the use of animal manure,» says Prof Graham from Newcastle University.

Based on their results, Gigi Ebenezer, M.B.B.S., M.D., assistant professor of neurology and the first author on the study, reported that protein clumps were detected in 70 percent of cases and 20 percent of patients who carried disease - causing genes but hadn't yet developed symptoms.

Nadeau stumbled upon one study, in mice, describing how environmental factors can tag Foxp3 with chemical markers that tell T - cell precursors to switch the gene on or off.

The aim of the study is to understand the impact of environmental factors, lifestyle factors and genes on health.