Not exact matches
In addition to shedding light
on how abnormal glia can cause
schizophrenia, the
study underlined how readily mouse brains accept human cells.
As of mid-February 2017, more than 544,000 Veterans have provided DNA specimens, military exposure information, and access to health records to facilitate
studies on topics ranging from the biological underpinnings of Gulf War illness and PTSD to
schizophrenia and bipolar disorder.
In the heady postwar years, hundreds of promising
studies were conducted in the United States, Canada, and Europe
on the use of LSD and other psychedelics, like peyote, to treat such psychiatric maladies as
schizophrenia, autism, drug addiction, alcoholism, and chronic depression.
A new
study by University of Maryland School of Medicine researchers has found that in mice, adjusting levels of a compound called kynurenic acid can have significant effects
on schizophrenia - like behavior.
Dr Antonio Pardiñas, first author of the
study, said: «We show for the first time that genetic variants that do not severely impact gene function, but presumably have a more subtle impact
on these critical genes, increase risk for developing
schizophrenia.»
In this
study, the researchers performed a series of electrophysiological and behavioral experiments
on a mouse model of
schizophrenia developed at CUMC.
Future
studies about romantic attachment will focus
on using the findings from research such as Young's and Diamond's to develop new treatments for grief associated with partner separation or loss and for disorders that involve social deficits, such as
schizophrenia and autism.
However, until now no
study has examined the effect of Holocaust exposure
on the risk of developing
schizophrenia.
A unique
study examining the effect of Holocaust exposure
on the risk of developing
schizophrenia was recently undertaken by Prof. Stephen Levine, Prof. Itzhak Levav Dr. Yair Goldberg of the University of Haifa; and Ms. Inna Pugachova, Ms. Yifat Becher, and Ms. Rinat Yoffe of the Ministry of Health.
Published in Nature Neuroscience, this new
study lends support to the direct influence
on creativity of genes found in people with
schizophrenia and bipolar disorder.
Although exercise has been shown to be an effective treatment for people with long - term
schizophrenia, no
studies have assessed its effects
on psychiatric symptoms in young adults with early psychosis, until now.
Sasson was
studying developmental psychology, with a focus
on autism, and Pinkham was interested in
schizophrenia and clinical psychology.
«Low birth weight and preterm birth have been proposed as risk factors in
schizophrenia in general, but past
studies have not shown a large effect
on risk,» says Dr. Bassett, who is also the Director of the Clinical Genetics Research Program at CAMH.
Schizophrenia risk From previous
studies, the researchers knew that one of the strongest genetic predictors of people's risk of
schizophrenia was found within a region of DNA located
on chromosome 6.
The
study is based
on a survey of 72 English - speaking outpatients with
schizophrenia in the San Diego area.
A recent generation of
studies of postmortem brain tissue from people with
schizophrenia, particularly from the laboratory of Professor David Lewis and his colleagues at the University of Pittsburgh, have shed light
on schizophrenia - related abnormalities in the interplay of the main excitatory neurons, pyramidal neurons, and a specific class of inhibitory nerve cells, called chandelier cells, in the prefrontal cortex.
New
study of effects of two genes
on schizophrenia may aid in quicker diagnoses and the development of new therapies
According to Halassa, the new research sets the stage for ever more detailed
studies on the complex behavior involved in how the mammalian brain pays attention to what's important, and especially how those neural circuits are broken in cases of attention - deficit diseases, such as ADHD, autism, and
schizophrenia.
For this
study, the team, which also included Bernard Crespi, an evolutionary biology professor at Simon Fraser University in British Columbia, and East Carolina University evolution professor Kyle Summers, focused
on 76 gene variations most strongly related to
schizophrenia.
Previous
studies on post-mortem brains and blood samples from patients with
schizophrenia indicated that their brains show differences in terms of vascularization.
«Loss of motivation is a core feature of
schizophrenia that we need to investigate with increased focus,» said Dr. Gary Remington, senior scientist with the CAMH Campbell Family Mental Health Research Institute who served as the senior investigator
on the
study team.
We will need to carry out further
studies with larger sample sizes to confirm the current findings, but we hope that, used in conjunction with medication and current psychological therapies, this could help people with
schizophrenia minimise the impact of their illness
on everyday life.»
This means that adoptees with high - genetic risk for
schizophrenia - related disorders did not have any measurable impact
on parental communication and care giving skills, or
on the functioning of the rest of the family, according to the OPAS rating system that was used to evaluate the families in the
study.
Future
studies of these cells are expected to shed light
on developmental diseases such as autism and
schizophrenia and malformations of brain development, including microcephaly, lissencephaly and neuronal migration disorders, they say, as well as age - related illnesses, such as Alzheimer's disease.
Meta - analysis investigates time perception and temporal information processing in patients with
schizophrenia on the basis of 68
studies from the past 65 years...
The serotonin (5 - HT) hypothesis of
schizophrenia arose from early
studies on interactions between the hallucinogenic drug LSD (D - lysergic acid diethylamide) and 5 - HT in peripheral systems.
Before we go into greater depth
on this
study we want to note that recently, we reported
on the theory that child abuse is a «cause» of
schizophrenia.
The evidence emerged from a linkage
study of Icelandic families that showed that
schizophrenia correlated with an area
on the eighth of the 23 pairs of human chromosomes.
I worked at Virginia Commonwealth University for more than 14 years, focusing
on genetic
studies of
schizophrenia and smoking addiction.
Describes gene - identification methods — emphasizing linkage and association
studies — used in research
on bipolar disorder and
schizophrenia.
Torrey's
study also found that some of the drugs used to treat
schizophrenia have an inhibiting effect
on Toxoplasma growth.
Its lifetime impact
on individuals and society is high, both in terms of years of healthy life lost to disability and in terms of financial cost, with
studies estimating the cost of
schizophrenia at over $ 60 billion annually in the U.S. alone.
«Because big genetic
studies have been done
on schizophrenia and autism and other diseases, you can calculate someone's risks of developing those diseases from their genetic information and you can see if it's associated with contagious yawning,» she said.
Her laboratory also uses mouse models to
study other neurogenetic diseases, such as
schizophrenia and ALS, with a focus
on genes that affect the course of disease and clinical outcomes.
Men who become fathers later in life pass
on more brand - new genetic mutations to their offspring, a
study has found — probably contributing to disorders such as autism and
schizophrenia in the next generation.
Studies showing correlative links between Toxoplasma gondii infection and potential increases in
schizophrenia, suicide attempts and poor impulse control have often been conducted
on small clinical or convenience samples, rather than large populations.
Their most recent
study, published in
Schizophrenia Research, along with researcher Wendy Simmons, compared two previous
studies that found a link between childhood cat ownership and the development of
schizophrenia later in life with an unpublished survey
on mental health from 1982, 10 years before any data
on cat ownership and mental illness had been published.
Converging effects of diverse treatment modalities
on frontal cortex in
schizophrenia: A review of longitudinal functional magnetic resonance imaging
studies.
Henry et al12 carried out a
study on 23 manic BD patients, 14 patients with
schizophrenia and 23 healthy controls.
Distinctions based
on age of onset have proven important for understanding heterogeneity within attention - deficit / hyperactivity disorder51 and antisocial disorder, 52,53 in which childhood onset has worse implications for course, recurrence, familial transmission, and treatment resistance.54 Research
on schizophrenia is also benefiting from a focus
on childhood neurodevelopmental processes55 and juvenile - onset symptoms.56 The present
study and others1 illustrate that the distinction between juvenile vs adult - onset MDD is important for understanding heterogeneity within depression as well.
A sross - cultural
study on expressed emotion in careers of people with dementia and
schizophrenia: Japan and England.
Some careers in child psychology might focus
on abnormal child psychology, which is a similar profession, but may focus more
on the
study and treatment of long term mood disorders,
schizophrenia, psychopathology, sociopathy, or other personality disorders.
In addition, several
studies have shown that other parental psychological disorders such as
schizophrenia and anxiety disorders are related to dysfunctional parenting practices, including a lack of parental monitoring and harsh parenting, although it should be noted that most of these
studies focused only
on mothers (Berg - Nielsen et al. 2002).
Kavanagh39 reported the median proportion of high EE families in their meta - analysis as 54 % with a range from 23 % to 77 %, whereas figures are typically lower than 40 % in staff - patient
studies.12, 23,24,27,28,40 — 42 It may be the case that psychiatric staff have both more experience and training in managing patients» problems than relatives which may be protective factors against the development of high EE.43 In support of this hypothesis, an early
study which involved interviewing nurses about how they cope with patients» symptoms of
schizophrenia found that more experienced senior staff used a greater number and range of coping strategies than less experienced staff.43 High EE ratings in staff - patient
studies are also almost exclusively based
on the presence of critical comments with infrequent hostility and very little evidence of EOI.
The influence of family Expressed Emotion
on the course of
schizophrenia in a sample of Spanish patients; a two year follow - up
study
This
study uses data from the Clinical Antipsychotic Trials of Intervention Effectiveness
on sociodemograhic characteristics, baseline clinical status, and service use among patients diagnosed with
schizophrenia to prospectively identify predictors of CJS involvement during the following year.
Effects of antipsychotic medications
on psychosocial functioning in patients with chronic
schizophrenia: findings from the NIMH CATIE
study
Several
studies have reported that early trauma, and especially childhood sexual abuse, specifically increases the risk of later hallucinations in both
schizophrenia and bipolar patients.69 — 73
On the other hand, insecure attachment appears to be specifically associated with paranoia and not hallucinations.45, 46 Evidence that discrimination or victimization plays a specific role in the development of paranoid beliefs has emerged from a population survey in the United States and Mexico, 39 from a prospective population - based
study in Holland, 32 and from patients» retrospective reports of their experiences of intrusive74, 75 and threatening76 life events (as noted above, this effect may contribute to the elevated rates of psychosis in immigrant populations).