Sentences with phrase «studies skin stem»
To learn more, her group, including postdoctoral fellow Maria Fernanda Forni, who studies skin stem cells, paired up with Jorge Shinohara in Sao Paulo's Fundamental Chemistry Department, who built a custom - made temperature sensor for mouse skin.
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«This new study uncovers for the first time the dynamic of stem cells during wound healing and identifies new molecular players associated with skin regeneration.
«It was particularly exciting to observe that the repair of the skin epidermis involves the activation of very different stem cells that react the same way to the emergency situation of the wound and have the power to completely restore the damaged tissue», comments Mariaceleste Aragona, the first author of the study.
Human epidermal equivalents representing different types of skin could also be grown, depending on the source of the stem cells used, and could thus be tailored to study a range of skin conditions and sensitivities in different populations.»
The disease model, described in a new study by a UC San Francisco - led team, involves taking skin cells from patients with the bone disease, reprogramming them in a lab dish to their embryonic state, and deriving stem cells from them.
In the present study, her team took skin cells from patients with lissencephaly and turned them into iPS cells, which they then cultivated under special conditions into neuronal stem cells and neurons that are copies of those in the patients» brains.
Since the same stem cells are responsible for helping heal the skin after injury, the study raises the possibility that Tregs may play a key role in wound repair as well.
«Use of induced pluripotent stem cell (iPSC) technology» — which involves taking skin cells from patients and reprogramming them into embryonic - like stem cells capable of turning into other specific cell types relevant for studying a particular disease — «makes it possible to model dementias that affect people later in life,» says senior study author Catherine Verfaillie of KU Leuven.
The team is also applying the approaches outlined in this paper to cells in the intestine and skin to study basic ideas of stem cell maintenance and differentiation to relate back to similar mechanisms in the heart.
Two approaches to fat grafting — injection of fat cells versus fat - derived stem cells — have similar effects in reversing the cellular - level signs of aging skin, reports a study in the April issue of Plastic and Reconstructive Surgery ®, the official medical journal of the American Society of Plastic Surgeons (ASPS).
In one study, geneticist Joseph Ecker at the Salk Institute in California took various stem cell lines reprogrammed from skin, fat, and other tissues and examined each line's genome for dna methylation, chemical marks that alter how genes are expressed.
In the new study, the researchers cultured mouse skin - cancer colonies on various 2 - D and 3 - D environments of different shapes and patterns to see if the tumor shape contributes to activation of cancer stem cells, and to see where in the tumor the stem cells appeared.
In a study published December 22 in Stem Cell Reports, researchers developed an alternative approach involving the direct conversion of adult skin cells into functional testosterone - producing cells.
The study carried out at the University of Eastern Finland used the induced pluripotent stem cell technology, which enables the generation of pluripotent stem cells from human skin fibroblasts.
For the new study, the team used a cell - reprogramming technique (similar to those used to reprogram skin cells into stem cells) to generate human DRG - type sensory neurons from ordinary skin cells called fibroblasts.
Creating heart cells from induced pluripotent stem cells (iPSCs) that are derived from a patient's skin cells enables scientists to study and test drugs on that patient's specific disease.
In this new study, the scientists mimicked human tissue formation by starting with stem cells genetically reprogrammed from adult skin tissue to form small chambers with beating human heart cells.
To study the underlying cause of bipolar disorder, Gage and his colleagues collected skin cells from six bipolar patients, reprogrammed the cells to become stem cells, and then coaxed the stem cells to develop into neurons.
Researchers at the Salk Institute for Biological Studies have, for the first time, taken chimpanzee and bonobo skin cells and turned them into induced pluripotent stem cells (iPSCs), a type of cell that has the ability to form any other cell or tissue in the body.
Skin cells from bonobos (pigmy chimps) were reprogrammed to pluripotent stem cells, an advance that allows scientists to study the differences between the neurons of humans and chimps.
He adds that the stem cells used in the study have advantages over reprogrammed skin cells, including eliminating the tricky business of inducing the cells to become muscle cells, but he notes that both types of cells could pose risks because the virus used to modify them could cause cancer.
New study shows that adult skin cells made to differentiate like embryonic stem cells may reverse neurological damage
The study results, published in the journal Cell, revolve around iPSCs, which since their 2006 discovery have enabled researchers to coax mature (fully differentiated) bodily cells (e.g. skin cells) to become like embryonic stem cells.
Now, in a study published in Nature, researchers led by Professor Cédric Blanpain at the Université Libre de Bruxelles, Belgium, and Professor Ben Simons at the University of Cambridge, have demonstrated in mice how skin stem and progenitor cells respond to the activation of an oncogene.
«From skin to brain: Stem cells without genetic modification: Study yields neural crest cells from adult skin cells, and could lead to new treatments for Parkinson's and other brain illnesses.»
Stem cells, derived from skin cells donated by people with and without bipolar disorder, allow scientists to study the disease at its most basic level.
Researchers studying the heterogeneous nature of cancer stem cell - containing skin tumors may have discovered new therapeutic targets
In this new study, the scientists mimicked human tissue formation by starting with stem cells genetically reprogrammed from adult skin tissue to small chambers with beating human heart cells.
Recently, his lab used induced pluripotent stem (iPS) cells — adult cells made to act like embryonic stem cells — made from skin cells of patients carrying apoE4, or other mutations related to Alzheimer's, to study their effects on the development, survival, and degeneration of human neurons.
Globs of human fat removed during liposuction conceal versatile cells that are more quickly and easily coaxed to become induced pluripotent stem cells, or iPS cells, than are the skin cells most often used by researchers, according to a new study from Stanford's School of Medicine.
They conducted a study in mice and found that the stem cell that produces all the different cells of the skin actually lives in hair follicles.
Cell Stem Cell «Recently three different studies were published demonstrating that mouse fibroblast (skin) cells can be directly reprogrammed to behave like embryonic stem cells.&raStem Cell «Recently three different studies were published demonstrating that mouse fibroblast (skin) cells can be directly reprogrammed to behave like embryonic stem cells.&rastem cells.»
There are studies on embryonic stem cells, which can make all the tissues of your body, and people over the past couple years have been able to take a set of genes and put them in and reprogram the skin cells to think they're an embryonic cell and therefore being able to make all the tissues of your body.
These studies reveal a crosstalk between the two conserved developmental pathways in human skin, and highlight the role of the skin microenvironment in driving the generation of stem cells, and possibly tumor - initiating cells.
They will continue this work with cells from Lurie patients as part of the study, and grow heart cells as well as neurons from stem cells derived from skin.
Gladstone scientists study how human skin cells can be reprogrammed into induced pluripotent stem (iPS) cells, and they are working to refine the production of these cells.
In the Science study, Ding's team used trial and error to find a combination of chemicals that could induce human skin cells to turn into multipotent stem cells, and then into cardiomyocytes.
In two studies published in Science and Cell Stem Cell, the team of scientists, who were led by Gladstone senior investigator Sheng Ding, PhD, and are part of the Roddenberry Center for Stem Cell Biology and Medicine at Gladstone, used chemical cocktails to gradually coax skin cells to change into organ - specific stem cell - like cells and, ultimately, into heart or brain ceStem Cell, the team of scientists, who were led by Gladstone senior investigator Sheng Ding, PhD, and are part of the Roddenberry Center for Stem Cell Biology and Medicine at Gladstone, used chemical cocktails to gradually coax skin cells to change into organ - specific stem cell - like cells and, ultimately, into heart or brain ceStem Cell Biology and Medicine at Gladstone, used chemical cocktails to gradually coax skin cells to change into organ - specific stem cell - like cells and, ultimately, into heart or brain cestem cell - like cells and, ultimately, into heart or brain cells.
The latest study, published in Cell Stem Cell, offers a third way to turn skin cells into stem cells by directly manipulating the cells» genome using CRISPR gene regulation techniqStem Cell, offers a third way to turn skin cells into stem cells by directly manipulating the cells» genome using CRISPR gene regulation techniqstem cells by directly manipulating the cells» genome using CRISPR gene regulation techniques.
Scientists at Gladstone now create stem cells from the skin cells of patients with a specific disease, which helps them to study the causes of disease and find novel treatments.
In the second study, authored by Gladstone postdoctoral scholar Mingliang Zhang, PhD, and published in Cell Stem Cell, the scientists created neural stem cells from mouse skin cells using a similar approStem Cell, the scientists created neural stem cells from mouse skin cells using a similar approstem cells from mouse skin cells using a similar approach.
They had previously studied the circadian clock in the basal state and then in skin stem cells.
By studying the stem cells in two types of tissue, namely skin, muscle, and in liver, in young (three months old) and aged (18 to 22 months old) mice every four hours, «we observed that the core components of the circadian clock had no changes in their rhythm with age».
To overcome these hurdles, Bhatia and her team reprogrammed human skin cells into induced pluripotent stem cells (iPSCs)-- embryonic - like stem cells capable of turning into other specific cell types relevant for studying a particular disease.