Not exact matches
A 2005
study published in the medical journal The Lancet found the approach was roughly
as effective
as a
placebo.
In one
study, subjects were shown a video — either of comedy routines or a «
placebo» video that wasn't
as funny.
The ENDEAVOUR Phase 3
study data monitoring committee recommended dosing be suspended after it found «an imbalance of mortality» in patients who used revusiran
as compared to
placebo.
While a few
studies have indicated that cupping may reduce pain and increase well being,
as The New York Times notes there's scant research to determine whether it's anything more than a
placebo effect.
There have been numerous
studies done that prove prayer doesn't do a damn thing outside of acting
as a
placebo.
One
study even goes so far
as to say that the herbs can work, but only
as a
placebo effect.
«A significant body of research has resulted in a shift from thinking of
placebos as just «dummy» treatments to recognizing that
placebo effects encompass numerous aspects of the health care experience and are central to medicine and patient care,» said the article's coauthor Ted Kaptchuk, Director of the Program in Placebo Studies at Beth Israel Deaconess Medical Center (BIDMC) and Professor of Medicine at Harvard Medical
placebo effects encompass numerous aspects of the health care experience and are central to medicine and patient care,» said the article's coauthor Ted Kaptchuk, Director of the Program in
Placebo Studies at Beth Israel Deaconess Medical Center (BIDMC) and Professor of Medicine at Harvard Medical
Placebo Studies at Beth Israel Deaconess Medical Center (BIDMC) and Professor of Medicine at Harvard Medical School.
According to the authors,
placebo effects can dramatically enhance the effectiveness of pharmaceutical therapies,
as shown in
studies of patients with irritable bowel disease and episodic migraine.
Study data also showed that type 2 diabetes developed in three times
as many people receiving
placebo as those who took liraglutide (14 subjects versus four, respectively).
This was the case in the new
study, published in the journal Archives of General Psychiatry — patients with major depressive disorder who were given a
placebo saw their symptoms improve about three quarters
as much
as those given paroxetine, an antidepressant also known
as Paxil.
As this study focuses on neurofeedback effects on EEG, sleep and quality of life in insomnia patients, insomnia patients underwent this procedure before and after real as well as placebo neurofeedback trainin
As this
study focuses on neurofeedback effects on EEG, sleep and quality of life in insomnia patients, insomnia patients underwent this procedure before and after real
as well as placebo neurofeedback trainin
as well
as placebo neurofeedback trainin
as placebo neurofeedback training.
But
studies such
as Petrovic's and Wager's linking
placebo effects to real neurobiological processes have painted a more nuanced picture.
Only one
study measured the participants» adult height: it found there was a 1.2 - centimetre difference between people who had used inhaled steroids
as a child and those who were given a
placebo.
According to a more recent
study, the drug could also help nondiabetic individuals lose weight
as well: Subjects who received the drug reported losing three times more weight over a six - month period than those who received a
placebo.
A
study testing Vioxx's ability to stem polyps in 2600 volunteers found that after 18 months, participants on Vioxx were twice
as likely to suffer a heart attack or stroke
as those on
placebo.
The varying doses,
as well
as the
placebo participants took, were all packaged the same so neither they or the investigators knew which dose, if any, they were getting until the
study was complete.
Widely hailed
as a «breakthrough» in HIV prevention by public health officials, the
studies — one of which dropped its
placebo arm today because of the convincing effects of the intervention — add powerful new tools to derail transmission of the virus in the population that accounts for most of the 34 million infections in the world.
TRINOVA - 2 is evaluating pegylated liposomal doxorubicin in combination with either
placebo or trebananib in previously treated patients with ovarian cancer while TRINOVA - 3, also known
as ENGOT - Ov2 and Gynecologic Oncology Group — 3001, is
studying the use of trebananib in front - line treatment adding it to carboplatin / paclitaxel.
Maharaj said he didn't use a
placebo group in his
study because it was too expensive and because he believes that the baseline assessment will allow participants to serve
as their own control.
Furthermore, the report accuses the British Homeopathic Association (BHA), which had submitted evidence to the panel, of cherry - picking, and even, in one case actively misrepresenting, research into the treatment (a famous
study that concluded its findings were «compatible with the notion that the clinical effects of homeopathy are
placebo effects» was cited by the BHA
as evidence of the treatment's efficacy.)
As part of the
study, groups of 18 to 20 female mice were vaccinated with one of the vaccines or a
placebo, and some animals received a second dose of the same vaccine or
placebo a month later.
Recent empirical
studies have shown that
placebos administered openly have clinically significant effects on physical complaints such
as chronic back pain, irritable bowel syndrome, episodic migraine and rhinitis.
Results of the second, larger
study were nearly
as impressive: 38 percent of patients who took baby aspirin developed new polyps, compared with 47 percent of patients taking the
placebo.
Although the
study began
as a randomized trial that divided subjects into four treatment groups (
placebo, deprenyl, α - tocopherol, and deprenyl / α - tocopherol), this was terminated early because positive effects of deprenyl were observed and all subjects then received deprenyl for approximately 18 months.
A new analysis of nine
studies conducted by Paxil's manufacturer, GlaxoSmithKline, showed that teenagers and children taking Paxil were more than three times
as likely
as those taking
placebos to think about and attempt suicide.
Medical psychologist Jack D. Edinger of Duke University and his colleagues conducted a two - and - a-half-year
study of 75 adults suffering from sleep maintenance insomnia in order to assess the efficacy of a form of cognitive behavioral therapy (CBT),
as compared with relaxation therapy and
placebo therapy.
Overall, the
studies suggested that the herb was more effective than a
placebo and just
as effective
as antidepressants such
as Prozac yet came with fewer side effects.
As in previous observational
studies, participants reported feeling less hungry during the week they consumed walnut - containing smoothies than during the week they were given the
placebo smoothies.
A second
study, which was another joint effort by UW and UCSF, randomized more than 600 people across the United States assessed
as moderately or mildly depressed to one of three interventions: Akili's Project: EVO; iPST, an app deployment of problem - solving therapy; or a
placebo control (an app called Health Tips, which offered healthy suggestions).
As this
study has shown in a randomized, double - blind, double - dummy,
placebo - controlled manner, exogenous testosterone therapy with Androgel can clearly decrease sperm production and potentially impact fertility,» said Dr. Kim.
Budimirovic says the current
study updated the 2013 recommendations by using a more systematic approach that classified existing outcome measures
as either being able to detect shorter - term changes (measures in FXS
placebo - controlled trials lasting less than 12 months) or longer - term changes (lasting longer than 12 months) changes and by grading the measures» quantitative properties using the COnsensus - based Standards for the selection of health Measurement Instruments (COSMIN) system, an initiative that aims to improve how health measurement tools are selected.
Experiments on five people who were given a caffeine pill or a
placebo pill a few hours before their normal bedtime and then exposed to dim or bright light showed that caffeine's effects were about half
as strong
as exposure to bright lights — one of the best -
studied ways to shift the body's clock.
«This
study opens up a new avenue of
studies for brain - based interventions,» he says, «such
as targeting the dopamine system» to increase the
placebo effect.
A new report on the ethics of Ebola, released today by the U.S. Presidential Commission for the
Study of Bioethical Issues, takes a nuanced view of the questions about study design; the committee doesn't rule out placebo - controlled studies but allows room for other designs as
Study of Bioethical Issues, takes a nuanced view of the questions about
study design; the committee doesn't rule out placebo - controlled studies but allows room for other designs as
study design; the committee doesn't rule out
placebo - controlled
studies but allows room for other designs
as well.
The fact that they all paid $ 8000 to be included,
as well
as the
study's lack of a
placebo group, has attracted much criticism.
The investigation was designed
as a randomized,
placebo - controlled
study.
Instead, the team chose only
studies that were
placebo - controlled, used tDCS
as a daily medical treatment, and involved at least 10 participants.
Labelling functions
as a «
placebo» in this
study.
A Phase III, Multicenter, Randomized,
Placebo - Controlled, Double - Blind
Study Of Atezolizumab (Anti − PD - L1 Antibody)
As Adjuvant Therapy In Patients With Renal Cell Carcinoma At High Risk Of Developing Metastasis Following Nephrectomy
A Phase III, Multicenter, Randomized,
Placebo - Controlled
Study of Atezolizumab (ANTI − PD - L1 Antibody)
as Monotherapy and in Combination with Platinum - Based Chemotherapy in Patients with Untreated Locally Advanced or Metastatic Urothelial Carcinoma
Yesterday, away from the conference, it was reported that the
placebo arm of a European trial
studying the antiretroviral Truvada used
as PrEP will be stopped early and volunteers will be offered the antiretroviral because of its observed effectiveness at preventing HIV infection.
The randomized, double - blind,
placebo - controlled
study will evaluate the safety and tolerability of multiple doses of NPT088,
as well
as pharmacokinetics, immunogenicity and pharmacodynamic characteristics,
as measured by Aβ and tau PET imaging.
Scientist have discovered a way to make neurons respond to a
placebo (a medically ineffective treatment), in the same way
as they would to medically effective treatment, according to a
study published
RV 172 was conducted by the MHRP network
as a multicentre
study involving 324 healthy HIV - 1 uninfected adult volunteers (186 receiving vaccine and 138 receiving
placebo) enrolled at MHRP» three East Africa sites:
CONCLUSIONS: Approximately 4.6 years after immunization with AN1792, patients defined
as responders in the phase 2a
study maintained low but detectable, sustained anti-AN1792 antibody titers and demonstrated significantly reduced functional decline compared with
placebo - treated patients.
The results were analyzed by comparing patients originally identified
as antibody responders in the AN1792 phase 2a
study with
placebo - treated patients.
We also performed subgroup meta - analyses by type of prevention (primary v secondary: in this
study, trials involving healthy populations or patients with any specific disease except for cardiovascular disease were classified
as primary prevention trials, and trials involving patients with cardiovascular disease were classified
as secondary prevention trials), type of supplement by quality and dose (each supplement, vitamins only, antioxidants only, or antioxidants excluding vitamins), type of outcome (cardiovascular death, angina, fatal or non-fatal myocardial infarction, stroke, or transient ischaemic attack), type of outcome in each supplement, type of
study design (randomised, double blind,
placebo controlled trial v open label, randomised controlled trial), methodological quality (high v low), duration of treatment (< 5 years v ≥ 5 years), funding source (pharmaceutical industry v independent organisation), provider of supplements (pharmaceutical industry v not pharmaceutical industry), type of control (
placebo v no
placebo), number of participants (≥ 10000 v < 10000), and supplements given singly or in combination with other vitamin or antioxidant supplements by quality.
Those
studies really seek to make sure that the drug is safe, and if a drug passes that Phase I safety trial they move on to a Phase II trial, where that drug is compared against a
placebo — so, no treatment or an existing drug to see if it performs
as well or better than the existing drug.
My go - to herbalist, author and American Herbalist Guild member David Winston of Broadway, New Jersey, says in his book, Herbal Therapy and Supplements: A Scientific and Traditional Approach, that animal and test - tube
studies are convincing enough to recommend eating maitake regularly
as part of a treatment plan for high cholesterol, high blood pressure, insulin resistance, and even hepatitis B. (
Placebo - controlled
studies in people have yet to be conducted.)
A cosmetics industry representative interviewed for this story pointed out that the EWG report «lacks many of the rigors that you would normally associate with a real scientific report,» such
as a large
study population and control or
placebo groups.