Sentences with phrase «study cell regeneration»

Not exact matches

«This new study uncovers for the first time the dynamic of stem cells during wound healing and identifies new molecular players associated with skin regeneration.

Immune cells are normally associated with fighting infection but in a new study, scientists have discovered how they also help the nervous system clear debris, clearing the way for nerve regeneration after injury.

This may be one of the most important facets of studying regeneration in these animals because they provide a completely different approach to tissue regeneration than that offered by stem cells.

We believe that they will also lead to the development of a whole new range of therapies for neurodegenerative diseases of the central nervous system,» explains corresponding author of the study Jihwan Song, professor and director of Neural Regeneration and Therapy Group at the CHA Stem Cell Institute of CHA University.

According to Izpisúa Belmonte, who is also a professor at the gene expression laboratories of the Salk Institute for Biological Studies in San Diego, California, CMRB aims to become «a research centre of excellence in south Europe in the line of world - recognized institutions such as the Salk or the Whitehead institutes, where both pre - and postdoctoral researchers receive multidisciplinary training of the highest quality» in stem cell biology and cell regeneration.

Today is the 70th birthday of Elizabeth Hay, an embryologist at Harvard Medical School who, through pioneering studies on regeneration of amphibian limbs, has shed light on the cellular mechanisms that transform normal cells into tumors.

«The discovery of the novel progenitor represents a fundamental advance in this field and potentially to the liver regeneration field using cell therapy,» said the study's senior author, Valerie Gouon - Evans, PharmD, PhD, Assistant Professor, in the Department of Developmental and Regenerative Biology, Black Family Stem Cell Institute, at the Icahn School of Medicine at Mount Sicell therapy,» said the study's senior author, Valerie Gouon - Evans, PharmD, PhD, Assistant Professor, in the Department of Developmental and Regenerative Biology, Black Family Stem Cell Institute, at the Icahn School of Medicine at Mount SiCell Institute, at the Icahn School of Medicine at Mount Sinai.

The c - MYC pathway appeared to some researchers to be an unlikely therapeutic target for beta cell regeneration because past studies had found it to cause beta cell death when activated in high doses.

Stephen Davies, a neuroscientist at the University of Colorado at Denver who studies nervous system regeneration using stem cells, is one of the key scientists working to overcome the obstacles in place.

«This is one of nature's most remarkable feats of regeneration,» said the study's senior investigator Kenneth Poss, professor of cell biology and director of the Regeneration Next initiatregeneration,» said the study's senior investigator Kenneth Poss, professor of cell biology and director of the Regeneration Next initiatRegeneration Next initiative at Duke.

A new study by researchers at Karolinska Institutet in Sweden shows how an unexpectedly high number of mutations in the stem cells of muscles impair cell regeneration.

Weissman says that most clinical studies of stem cells fail to meet what he sees as key criteria: They should be based on clear, peer - reviewed demonstrations of tissue regeneration, replicated by a large number of independent groups that provide rapid, long - lasting benefits.

The finding made intuitive sense; researchers studying other tissue types had shown that activating mTOR can drive dormant cells out of quiescence, a necessary step for regeneration.

In the new study, Makarenkova and her colleagues looked at whether they could kick start regeneration by injecting progenitor cells into the lobes that make up the lacrimal gland.

«The worm was initially used as a model to study embryology and neurobiology, and starting in the late 1990s research expanded into stem cell biology, tissue homeostasis, and regeneration, topics that are still very actively studied today,» he says.

«Our study found that by introducing an inhibitor of the STAT3 protein in repeated cycles, we could alternately replenish the pool of satellite cells and promote their differentiation into muscle fibers,» said Alessandra Sacco, Ph.D., assistant professor in the Development, Aging, and Regeneration Program at Sanford - Burnham.

Next, to study regeneration, he selectively destroyed the mice's pancreatic cells using a particularly toxic chemotherapy drug.

The study marks an important step toward the goal of organ regeneration, Badylak says, but more work is needed to ensure that cells in the regenerated organs know when to stop growing and what shape to take.

The study used novel gene expression methods that allowed the researchers to identify over one thousand genes that are involved in the regeneration process of individual stentor cells.

«Our results suggest that megakaryocytes might be used clinically to facilitate adult stem cell regeneration and to expand cultured cells for adult stem cell transplants,» says Meng Zhao, Ph.D., a postdoctoral fellow at Stowers and lead author on the study.

The study, «Facilitation of axon regeneration by enhancing mitochondrial transport and rescuing energy deficits,» which has been published in The Journal of Cell Biology, suggests potential new strategies to stimulate the regrowth of human neurons damaged by injury or disease.

«We also managed to confirm observations from previous microscopy studies that suggested that cellular regeneration shares similarities with the process of cell division.

In further studies, the scientists then found clear evidence of a so - called transdifferentiation of cells: The muscle cells of the atria of the heart of the fish lost their characteristic properties and subsequently transformed into ventricular cells in the course of regeneration.

In a new study, published in Current Biology this week, a research team from Uppsala University reports new insights into the regenerative capabilities of Stentor, a single celled model organism for regeneration biology.

A new study establishes that the injection of a collagen - based biomaterial can mobilize endogenous stem cells to promote kidney regeneration in a mouse model

The authors were led into the realm of muscle and sex when they realized that they were relying heavily on cell lines derived from female mice to study muscle regeneration.

The study used novel gene expression methods that allowed the researchers to identify over one thousand genes involved in the regeneration process of individual stentor cells.

Esther Schnapp (Tanaka, MPG)-- «Studying the molecular mechanisms for generating progenitor cells during tail regeneration in ambystoma mexicanum» (2005)

Martin Kragl (Tanaka, MPG)-- «Studying the patterning mechanisms and cell fates during limb regeneration in Ambystoma mexicanum» (2007)

Towards our goals we study retinal cells throughout their life, from embryonic stem cells to retinal progenitors to differentiating and mature neurons and glia — with one eye on neuronal regeneration (meaning de-novo neurogenesis) in the mammalian retina — and with another eye on retinal disease pathomechanisms.

Although he is optimistic about the outcome, Izpisúa Belmonte also feels that the study should caution researchers not to overlook potential contributions that mature cells might make to regeneration.

In this study, Chazaud et al., evidenced that endothelial cells (ECs) and myogenic progenitor cells (MPCs) interacted to couple myogenesis and angiogenesis during skeletal muscle regeneration.

In collaboration with experimentalists we use these methods to study self - organization phenomena of cell populations in tissue development, disease and regeneration.

The study, published online February 20, 2018, in Cell Reports, was conducted by the UCSF lab of Saul Villeda, PhD, an assistant professor of anatomy and member of the Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research at UCSF.

The CFC [Catalyst for a Cure] funding made it possible for me to transition half my laboratory into the study of glaucoma and neural repair and ganglion cell repair and regeneration.

In a new STEM CELLS Translational Medicine study, Zhang et al. now report that the overexpression of Platelet - Derived Growth Factor - BB (PDGF - BB), a well - known potent mitogenic, angiogenic, and chemoattractive agent, can significantly enhance dental tissue regeneration [5].

Studies of satellite cell activation via nitric oxide have opened an exciting area of research on muscle regeneration, growth and the muscle - fiber cytoskeleton that integrates mechanical and biochemical signal transduction with cell and molecular biology of muscle tissue in growth, development, disease, aging and evolution.

The study supports the idea that patients with coronary artery disease may benefit from cardiac rehab programs, which drive the progenitor cells into the ischemic tissue, so they can contribute into vascular repair and regeneration.

In a proof - of - principle study published in the journal Cell Stem Cell, the researchers report that defects in the regeneration of the myelin sheaths surrounding nerves, which are lost in diseases such as multiple sclerosis may be at least partially corrected following exposure of an old animal to the circulatory system of a young animal.

However, a new study from the laboratory of James J. Yoo (Wake Forest School of Medicine, North Carolina, USA) now suggests that regeneration may not require exogenous stem cells, and biomaterial alone may suffice to repair damage to the kidney [3]!

Biologically, the hair follicle is an excellent system to study complex cyclic processes like regeneration that involve regulated growth, differentiation and cell death.

In this study, we will examine whether glial cells and certain proteins secreted from these cells influence axon regeneration and guidance in the optic nerve in adult mice.

3/29/2007 UCSD Researchers Identify Critical Receptor in Liver Regeneration In studies in mouse models, researchers at the University of California, San Diego (UCSD) School of Medicine have found that A hepatic stellate cell activated by the p75 Neurotrophin Receptor promotes repair in the livera cellular recept... More...

Our new study uses transcriptomics of cell fragments of the ciliate Stentor to reveal the importance of protein phosphorylation, microtubule - based processes and genes involved in the cell cycle for cellular regeneration.

A new study from the Harvard John A. Paulson School of Engineering and Applied Sciences (SEAS) and the Wyss Institute for Biologically Inspired Engineering at Harvard University suggests that mechanically - driven therapies that promote skeletal muscle regeneration through direct physical stimulation could one day replace or enhance drug and cell - based regenerative treatments.

Two studies find adult pancreatic cells maintain islet population, contradicting a hypothesis that regeneration relies on stem cells

His laboratory at Stanford University School of Medicine is developing novel stem cell and nanotherapeutics approaches for ocular repair, studying retinal ganglion cell development, survival and axon regeneration in glaucoma, and investigating the cellular basis for the developmental loss of axon growth ability.

«This collaboration fits in very well with our approach, which is to use diverse animal models to study the basic mechanisms of aging and tissue regeneration,» said assistant professor Aric Rogers, Ph.D. «The role of triggers in the cell's genetic machinery is a fruitful new avenue of research.

In a 2014 study conducted at UC Davis and published in Cell Stem Cell, prolonged fasting — periods of no food for two to four days at a time — induced immune system regeneration, shifting stem cells from dormant to self - renewing.

Cell energy (of which in their study on bone regeneration creatine played a major role) is important for bone development and maintenance, and therefore directly related to osteoporosis.