Sentences with phrase «study cellular responses»

The cell density of cartilage is also very low, therefore, cell cultures offer an easier approach to study cellular responses of chondrocytic cells, e.g., to mechanical stimuli.
RNA sequencing (RNA - seq) is a genomic approach for the detection and quantitative analysis of messenger RNA molecules in a biological sample and is useful for studying cellular responses.

Not exact matches

Another study found that maltodextrin impairs cellular antibacterial responses and suppresses intestinal antimicrobial defense mechanisms, leading to inflammatory bowel disease and other GI conditions that arise from an inappropriate immune response to bacteria.
For instance, Dawson says, Autism Speaks is funding studies investigating the idea that disorders in the cellular powerhouses, mitochondria, might influence responses to immune challenges such as infection and immunization.
Merryman's research into CDH - 11 dates back to 2013, when two of his Ph.D. students compared two studies of heart valve cellular responses that came to completely different conclusions.
Interest in studying tRNA fragments has been increasing swiftly as studies have shown that the fragments have regulatory roles and implicated individual fragments in cellular processes such as translation initiation, response to viral infection, response to DNA damage, etc..
Scientists use it as a model organism for studying cellular signals, disease, and the movement of cells in response to a chemical stimulus (chemotaxis).
To begin to explore the cellular mechanisms that might be responsible for this response, histological analysis revealed less severe disruption of spermatogenesis and gene expression studies suggested that an interplay of ATP - binding cassette (ABC) efflux transporters and solute carrier (SLC) influx transporters in the testicular cells might be involved.
Looking forward, the researchers are applying their approach to study cellular drug responses in clinical samples, but also aim to make their methods widely accessible.
We produce live and inactivated viruses in our BSL2 and BSL3 facilities, and perform immunogenicity and efficacy studies in pigs (influenza) and sheep (RSV) with a focus on skin vaccination and extended monitoring of humoral and cellular immune responses in the blood and lung.
Previous studies have found proteins and cellular factors involved in rapid - response energy dissipation when light intensity suddenly changes, such as when clouds move past the sun.
Numerous studies have demonstrated activity of these agents against a wide variety of cancers, especially cancer stem cell - like subpopulations, by a host of different mechanisms which comprise inhibition of signaling pathways, of mitochondrial respiration, as well as of cellular stress responses and others.
She and her colleagues study the cellular and molecular aspects of the innate and adaptive immune responses (the two arms of the immune system), and more specifically, dendritic cells, a specialized subset of leukocytes that coordinate them.
A Phase 1 study in malaria - naïve North American volunteers found that the AMA1 - based vaccine FMP2.1 / AS02A elicited potent humoral and cellular immune responses and that immune sera recognized sporozoites and merozoites by immunofluorescence assay and inhibited both parasite growth and AMA1 processing in homologous 3D7 parasites [16].
Systems biology aims to study complex cellular systems by systematically stimulating them, monitoring cellular responses, formulating mathematical and computational models to understand the data, and proposing new experiments to refine these models.
Therefore the group studies with sophisticated imaging technology in vitro and ex vivo: i) the molecular mechanism driving the migration of HIV through the intestinal epithelial barrier; ii) the cellular targets in the mucosa, in specific macrophages and DCs, to identify the possible pathways to invade the tissue and disseminate to other organs; iii) the involvement of DCs and their functional properties in mediating adaptive immune responses at mucosal level; and iv) the role of antibodies with different effector functions in changing the pathways of the virus.
Manuscripts typical of this section would describe experiments generating and analyzing lists of genes and studies of how those genes combine to regulate: differentiation of a particular cell type; cellular, tissue, or organ response to toxic / pathogenic agents; adaptation to environmental stresses.
Immunogenicity and efficacy studies in pig (influenza) and sheep (RSV) with a focus on skin vaccination and extended monitoring of humoral and cellular immune responses in the blood and lung.
Our finding highlights a key aspect of cellular transplantation not fully addressed in many short or long - term studies of RPE transplantation: the host inflammatory / immune response to the xenograft and its indirect role in the preservation of the retina.
Moreover, the data can serve as a basis for studies concerning the evolution of signaling mechanisms, as well as can give specific insights into the regulation of basic cellular processes such as polar cell growth, cell expansion, plant morphogenesis and the plants responses to fungal pathogens.
The study revealed that the immune system can be stimulated with a single session of 20 minutes of moderate exercise, which produces an anti-inflammatory cellular response.
Are there any respectable studies that show, on a cellular level, that slow fiber is slow, and nothing else, that fast fiber is fast and nothing else, or could these be just particular adaptations that single fibers are capable of in response to the tasks put before them?
To identify this protective mechanism, Nagler and her team studied cellular and molecular immune responses to bacteria in the gut.
The chart below summarizes a study that found there may not be as much to it as we think, other than simply chasing the muscle pump to elicit blood flow response and anabolic triggering, cellular swelling, hypertrophy, etc..
Our study also suggests that cellular responses to future ocean conditions are not likely to be straightforward, as shifts in calcification may have less to do with calcification - related genes and more to do with intracellular regulatory processes in cells grown under continuous culture for many hundreds of generations.
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