For his 2013 SENS Research Foundation Summer Internship, Ethan joined the laboratory of Dr. Judith Campisi at the Buck Institute for Research on Aging to
study cellular senescence, the process by which damaged cells enter irreversible growth arrest.
Not exact matches
Investigators
studied liver tissue from patients with steatohepatitis, who were heavy alcohol drinkers, and from ethanol - fed mice to identify biochemical markers of
cellular senescence.
Some of the leading folk in the
cellular senescence research community today published the results from a very encouraging life span
study, extending life in mice via a method of removing senescent cells.
Again, then, there is significant evidence consistent with a role of
cellular senescence in age - related lipodystrophy and lipoatrophy, and for the benefits observed in treated mice in these
studies to translate into aging humans.
In particular, they are focused on
studying the functional role and molecular mechanisms of
cellular senescence in both of these events, and how a deregulation of normal epithelial stem cell proliferation is involved.
Excitingly, our
study points out that condensin plays an important role in
cellular senescence, a major tumor suppression mechanism.
Studies have shown gamma - tocotrienol selectively targets cancer cells, triggering
cellular senescence and promoting apoptosis — a type of programmed cell suicide.