Sentences with phrase «study disease processes»

Many of the selected genes will be used to study disease processes and underlying mechanisms.

With so much work needed in studying the nature of stem cells and using them to study disease processes, therapies based on ES cells seem very far down the line, noted Lorenz Studer of Memorial Sloan - Kettering Cancer Center in New York, who pointed out that so far there have only been two published papers on therapeutic cloning, both of them in mice.

The research approach is called multi-scale modeling or MSM, to reflect the ability to study disease processes at the molecular, cellular, and tissue levels as well as interactions occurring between the levels.

In the short term, such artificial tissues could help researchers study disease processes and test new drugs in the lab.

It is now almost routine to grow skin cells from a patient with, say, a neurological disease; turn them into pluripotent cells in a Petri dish; convert the cells into nerve cells to study the disease process; and contemplate using the cells to repair the same patient's damaged brain.

Not exact matches

While studies have found that oats are safe for the vast majority of those with celiac disease, they can be contaminated by wheat, rye or barley during farming, processing and storage.

He has contributed to the study of the brain processing of form, symmetry, flicker, motion, color, and stereoscopic depth perception and has developed tests for the diagnosis of retinal and optic nerve diseases.

This is demonstrated in the studies reviewed in the special issue, which use computational models to examine brain processes, such as learning, emotion, dopamine signaling and information processing, and how processes interact in deficits underlying psychiatric disease.

«Population studies have consistently supported a protective role of nuts against cardiometabolic disorders such as cardiovascular disease and type 2 diabetes, and we know that inflammation is a key process in the development of these diseases,» said corresponding author Ying Bao, MD, ScD, an epidemiologist in BWH's Channing Division of Network Medicine.

The study of these highly unusual but devastating prion diseases has to date been thwarted by a lack of animal models that faithfully mimic the disease processes in humans.

Scientists have shifted from studying single molecules to investigating large complexes of interacting biological macromolecules involved in processes such as metabolic pathways, gene expression, and development of disease.

They also set reference points for future studies looking at the connection between metabolic processes and diseases such as cancer.»

These so - called endometrial organoids promise to shed light onto the processes that occur during the monthly menstrual cycle and open up the possibility of studying diseases of the uterus, such as endometrial atrophy (thinning of the lining) or cancer, in a lab culture system.

Specifically, the study authors were able re-create lupus disease processes, including the formation of antibodies to DNA and kidney inflammation, by engineering mice that lacked the gene for DNASE1L3.

«This opens a new door in identifying biological markers for dementia since we might consider using the brain's processing of speech sounds as a new way to detect the disease earlier,» says Dr. Claude Alain, the study's senior author and senior scientist at Baycrest's Rotman Research Institute (RRI) and professor at the University of Toronto's psychology department.

So, over the next 6 years, she worked as a research assistant in a diabetes lab, a process engineer at a paper mill, and a research associate in a lab studying diabetes and bone disease.

«This study shows that domesticated animals can play an important role in that process and that diseases have been shared in this way for thousands of years.»

This study was designed to better define the process by which ALS progresses and to explore the role of brain motor neurons in disease development and progression.

Alzheimer's is an agonizingly slow process, so by the time we get to study the disease itself during its late stages, all kinds of things have gone on that may be just consequences of disease rather than causal.

Because there's evidence that the words we hear and the words we recall or imagine trigger similar brain processes, the study, published online today in PLoS Biology, suggests scientists may one day be able to tune in to the words you're thinking — a potential boon for patients who are unable to speak due to Lou Gehrig's disease or other conditions.

Further studies of processes in which GTPBP3 is involved will help towards the understanding of human diseases that are linked to mitochondrial DNA expression and to develop new therapies.

«These two studies highlight the value of using an integrated multi-systems approach — including fruit flies, mice, and human cells — to discover mechanisms underlying disease processes.»

Future functional studies are needed to test whether these accelerated regions control disease processes in people.

The same process has been studied as a potential genetic therapy for more than a decade, because you can target any disease gene with matching dsRNA.

While the effects in mice are distinct from what happens in people with herpes, the study reveals a previously unrecognized disease process.

For years, scientists who study lung diseases like cystic fibrosis have tried to track this process in detail, from start to finish, in the hope that understanding how lungs form normally may help explain how things go wrong.

Findings from the study could help improve understanding of the causes of some diseases — including cancer — that are triggered by errors in the cell division process, the team says.

Intervening with an antioxidant early in the disease process may break the degenerative cycle and improve neuron function in PD, the study showed.

Viruses can't survive without a host, and the most - studied viruses linked to disease are lytic in nature: They get inside a cell and make copies of themselves, destroying the cell in the process.

Recent studies have centered on potential water pollution from this process that may increase endocrine disrupting chemicals (EDCs) in surface and ground water and whether populations living near these operations have an increased risk of disease.

A new study from The Scripps Research Institute (TSRI) is the first to show precisely how a process in nerve cells called the S - nitrosylation (SNO) reaction — which can be caused by aging, pesticides and pollution — may contribute to Parkinson's disease.

But study authors warn they still don't know the specific processes by which TBI appears to be associated with Alzheimer's disease, and are unable to predict in individual cases who is more likely to develop dementia later in life.

«Dr. Guo's study has identified a new mechanism of efficiently inhibiting biological processes that are critical to the function of the disease - causing organism, such that resistance is minimized or eliminated.»

Alzheimer's disease can be hard to definitively diagnose, but one study's findings could make the process much easier and more accurate.

Many U.S. adults consume more added sugar (added in processing or preparing of foods, not naturally occurring as in fruits and fruit juices) than expert panels recommend for a healthy diet, and consumption of added sugar was associated with increased risk for death from cardiovascular disease (CVD), according to a study published by JAMA Internal Medicine, a JAMA Network publication.

Wolynes considers the new study a beachhead to launch others to determine the entire process of how memories form, as well as the implications for diseases like Alzheimer's and Parkinson's that involve protein aggregation.

Getting Alzheimer's drugs to market requires long and costly clinical studies, which some experts say have failed thus far because experimental drugs were tested too late in the disease process.

Splitting the cow's milk proteins in a formula doesn't prevent the start - up of the disease process of type 1 diabetes in predisposed children, shows a large international study.

At ABclonal, we have nearly 100 existing chromatin immunoprecipitation (ChIP)- validated antibodies with a higher specificity than most commercial antibodies, which are used for a wide range of epigenetics studies, from those investigating developmental processes to those researching various diseases.

As noted in the study by Crimmins and lead author Morgan E. Levine, assistant professor at the Yale Center for Research on Aging: «A deceleration of the human aging process, whether accomplished through environment or biomedical intervention, would push the timing of aging - related disease and disability incidence closer to the end of life.»

«With this study, we have gained new knowledge about the disease processes in the brain in the early initial stages of the disease development.

Though the DNA sequence in question was not known, Kornberg hoped the achievement would aid studies of genetics and the search for cures for diseases, and reveal the most basic processes of life itself.

That's the claim of a new study, which finds increases in metabolic disease and intestinal inflammation in mice fed two common emulsifiers used in processed food.

The detailed study of such fundamental cellular processes is crucial for the understanding of diseases that go hand in hand with these events — in the case of autophagy, Alzheimer's disease or cancer.

That is when studies finally convinced scientists that the minuscule RNA snippets they had taken to calling «microRNA» were regulating cellular and genetic processes throughout the human body and were critical factors in the determination of health and disease.

«Our study suggests that the disease process and antibiotic treatment could have a far greater impact on intestinal microbial diversity than surgical intervention,» said Minna Wieck, MD, an investigator and surgical resident at CHLA and first author on the study.

Dr Margaret O'Hara, from the Molecular Physics Group and primary investigator on the project, said: «Previous studies have found potential biomarkers for liver disease, such as isoprene and acetone, but they are not specific enough because they are possible biomarkers for other diseases or can arise from numerous normal metabolic processes.

«There is a growing appreciation for the role of diverse bacteria in contributing to improved health as well as triggering disease processes or exacerbating illness,» says Michael H. Hsieh, M.D., Ph.D., director of the Clinic for Adolescent and Adult Pediatric Onset Urology (CAPITUL) at Children's National Health System and study senior author.

For now, they don't have a clue about the virus's origins or why it's suddenly causing an outbreak; in order to speed up the process, they want to share the virus and protocols for detecting it with anyone interested in studying the disease or developing diagnostic tools and vaccines.

«In gene carriers, before they show signs of the disease, the neurodegeneration process has already started,» says Sarah Tabrizi, a neurologist at University College London and coauthor of the study, which appears in The Journal of Experimental Medicine.